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Volumn 376, Issue 1-2, 2013, Pages 23-32

The nuclear localization signal is required for nuclear GPER translocation and function in breast Cancer-Associated Fibroblasts (CAFs)

Author keywords

Breast cancer; Cancer associated fibroblasts; Estrogen signaling; GPER; Nuclear localization signal

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; ESTROGEN; ESTROGEN RECEPTOR; G PROTEIN ESTROGEN RECEPTOR; KARYOPHERIN; PROTEIN C FOS; UNCLASSIFIED DRUG;

EID: 84879476386     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.05.023     Document Type: Article
Times cited : (61)

References (91)
  • 1
    • 82555196948 scopus 로고    scopus 로고
    • Role of cancer-associated fibroblasts in breast cancer development and prognosis
    • Aboussekhra A. Role of cancer-associated fibroblasts in breast cancer development and prognosis. Int. J. Dev. Biol. 2011, 55:841-849.
    • (2011) Int. J. Dev. Biol. , vol.55 , pp. 841-849
    • Aboussekhra, A.1
  • 3
    • 33847755409 scopus 로고    scopus 로고
    • G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17β-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
    • Albanito L., Madeo A., Lappano R., Vivacqua A., Rago V., Carpino A., Oprea T.I., Prossnitz E.R., Musti A.M., Andò S., Maggiolini M. G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17β-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Res. 2007, 67:1859-1866.
    • (2007) Cancer Res. , vol.67 , pp. 1859-1866
    • Albanito, L.1    Madeo, A.2    Lappano, R.3    Vivacqua, A.4    Rago, V.5    Carpino, A.6    Oprea, T.I.7    Prossnitz, E.R.8    Musti, A.M.9    Andò, S.10    Maggiolini, M.11
  • 5
    • 84861535861 scopus 로고    scopus 로고
    • New advances on the functional cross-talk between insulin-like growth factor-I and estrogen signaling in cancer
    • Bartella V., De Marco P., Malaguarnera R., Belfiore A., Maggiolini M. New advances on the functional cross-talk between insulin-like growth factor-I and estrogen signaling in cancer. Cell. Signal. 2012, 24:1515-1521.
    • (2012) Cell. Signal. , vol.24 , pp. 1515-1521
    • Bartella, V.1    De Marco, P.2    Malaguarnera, R.3    Belfiore, A.4    Maggiolini, M.5
  • 6
    • 33846644450 scopus 로고    scopus 로고
    • Nuclear import and export signals are essential for proper cellular trafficking and function of ZIC3
    • Bedard J.E., Purnell J.D., Ware S.M. Nuclear import and export signals are essential for proper cellular trafficking and function of ZIC3. Hum. Mol. Genet. 2007, 16:187-198.
    • (2007) Hum. Mol. Genet. , vol.16 , pp. 187-198
    • Bedard, J.E.1    Purnell, J.D.2    Ware, S.M.3
  • 8
    • 0041706091 scopus 로고    scopus 로고
    • Functional endothelin receptors are present on nuclei in cardiac ventricular myocytes
    • Boivin B., Chevalier D., Villeneuve L.R., Rousseau E., Allen B.G. Functional endothelin receptors are present on nuclei in cardiac ventricular myocytes. J. Biol. Chem. 2003, 278:29153-29163.
    • (2003) J. Biol. Chem. , vol.278 , pp. 29153-29163
    • Boivin, B.1    Chevalier, D.2    Villeneuve, L.R.3    Rousseau, E.4    Allen, B.G.5
  • 11
    • 38849110896 scopus 로고    scopus 로고
    • A sexually dimorphic distribution pattern of the novel estrogen receptor G-protein-coupled receptor 30 in some brain areas of the hamster
    • Canonaco M., Giusi G., Madeo A., Facciolo R.M., Lappano R., Canonaco A., Maggiolini M. A sexually dimorphic distribution pattern of the novel estrogen receptor G-protein-coupled receptor 30 in some brain areas of the hamster. J. Endocrinol. 2008, 196:131-138.
    • (2008) J. Endocrinol. , vol.196 , pp. 131-138
    • Canonaco, M.1    Giusi, G.2    Madeo, A.3    Facciolo, R.M.4    Lappano, R.5    Canonaco, A.6    Maggiolini, M.7
  • 13
    • 84858750488 scopus 로고    scopus 로고
    • 17β-Estradiol activates GPER- and ESR1-dependent pathways inducing apoptosis in GC-2 cells, a mouse spermatocyte-derived cell line
    • Chimento A., Sirianni R., Casaburi I., Ruggiero C., Maggiolini M., Andò S., Pezzi V. 17β-Estradiol activates GPER- and ESR1-dependent pathways inducing apoptosis in GC-2 cells, a mouse spermatocyte-derived cell line. Mol. Cell. Endocrinol. 2012, 355:49-59.
    • (2012) Mol. Cell. Endocrinol. , vol.355 , pp. 49-59
    • Chimento, A.1    Sirianni, R.2    Casaburi, I.3    Ruggiero, C.4    Maggiolini, M.5    Andò, S.6    Pezzi, V.7
  • 15
  • 16
  • 17
    • 0033587167 scopus 로고    scopus 로고
    • Structure of importin-beta bound to the IBB domain of importin-alpha
    • Cingolani G., Petosa C., Weis K., Müller C.W. Structure of importin-beta bound to the IBB domain of importin-alpha. Nature 1999, 399:221-229.
    • (1999) Nature , vol.399 , pp. 221-229
    • Cingolani, G.1    Petosa, C.2    Weis, K.3    Müller, C.W.4
  • 18
    • 84862313154 scopus 로고    scopus 로고
    • Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
    • Cirri P., Chiarugi P. Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression. Cancer Metast. Rev. 2011, 31:195-208.
    • (2011) Cancer Metast. Rev. , vol.31 , pp. 195-208
    • Cirri, P.1    Chiarugi, P.2
  • 22
    • 33751272253 scopus 로고    scopus 로고
    • Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression
    • Filardo E.J., Graeber C.T., Quinn J.A., Resnick M.B., Giri D., DeLellis R.A., Steinhoff M.M., Sabo E. Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinicopathologic determinants of tumor progression. Clin. Cancer Res. 2006, 12:6359-6366.
    • (2006) Clin. Cancer Res. , vol.12 , pp. 6359-6366
    • Filardo, E.J.1    Graeber, C.T.2    Quinn, J.A.3    Resnick, M.B.4    Giri, D.5    DeLellis, R.A.6    Steinhoff, M.M.7    Sabo, E.8
  • 23
    • 0033780783 scopus 로고    scopus 로고
    • Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF
    • Filardo E.J., Quinn J.A., Bland K.I., Frackelton A.R. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF. Mol. Endocrinol. 2000, 14:1649-1660.
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1649-1660
    • Filardo, E.J.1    Quinn, J.A.2    Bland, K.I.3    Frackelton, A.R.4
  • 24
    • 0036140032 scopus 로고    scopus 로고
    • Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis
    • Filardo E.J., Quinn J.A., Frackelton A.R., Bland K.I. Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Mol. Endocrinol. 2002, 16:70-84.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 70-84
    • Filardo, E.J.1    Quinn, J.A.2    Frackelton, A.R.3    Bland, K.I.4
  • 25
    • 34347238583 scopus 로고    scopus 로고
    • Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane
    • Filardo E.J., Quinn J.A., Pang Y., Graeber C., Shaw S., Dong J., Thomas P. Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane. Endocrinology 2007, 148:3236-3245.
    • (2007) Endocrinology , vol.148 , pp. 3236-3245
    • Filardo, E.J.1    Quinn, J.A.2    Pang, Y.3    Graeber, C.4    Shaw, S.5    Dong, J.6    Thomas, P.7
  • 26
    • 84862737860 scopus 로고    scopus 로고
    • Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology
    • Filardo E.J., Thomas P. Minireview: G protein-coupled estrogen receptor-1, GPER-1: its mechanism of action and role in female reproductive cancer, renal and vascular physiology. Endocrinology 2012, 153:2953-2962.
    • (2012) Endocrinology , vol.153 , pp. 2953-2962
    • Filardo, E.J.1    Thomas, P.2
  • 27
    • 75749118309 scopus 로고    scopus 로고
    • A new membrane G protein-coupled receptor (GPR30) is involved in the cardiac effects of 17beta-estradiol in the male rat
    • Filice E., Recchia A.G., Pellegrino D., Angelone T., Maggiolini M., Cerra M.C. A new membrane G protein-coupled receptor (GPR30) is involved in the cardiac effects of 17beta-estradiol in the male rat. J. Physiol. Pharmacol. 2009, 60:3-10.
    • (2009) J. Physiol. Pharmacol. , vol.60 , pp. 3-10
    • Filice, E.1    Recchia, A.G.2    Pellegrino, D.3    Angelone, T.4    Maggiolini, M.5    Cerra, M.C.6
  • 28
    • 79960977764 scopus 로고    scopus 로고
    • The role of nuclear pore complex in tumor microenvironment and metastasis
    • Funasaka T., Wong R.W. The role of nuclear pore complex in tumor microenvironment and metastasis. Cancer Metast. Rev. 2011, 30:239-251.
    • (2011) Cancer Metast. Rev. , vol.30 , pp. 239-251
    • Funasaka, T.1    Wong, R.W.2
  • 31
    • 0037805549 scopus 로고    scopus 로고
    • Basement membranes: structure, assembly and role in tumour angiogenesis
    • Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat. Rev. Cancer 2003, 3:422-433.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 422-433
    • Kalluri, R.1
  • 33
    • 0242268883 scopus 로고    scopus 로고
    • Tumor reversion: correction of malignant behavior by microenvironmental cues
    • Kenny P.A., Bissell M.J. Tumor reversion: correction of malignant behavior by microenvironmental cues. Int. J. Cancer 2003, 107:688-695.
    • (2003) Int. J. Cancer , vol.107 , pp. 688-695
    • Kenny, P.A.1    Bissell, M.J.2
  • 34
    • 82355188243 scopus 로고    scopus 로고
    • Minireview: putting physiology back into estrogens' mechanism of action
    • Koos R.D. Minireview: putting physiology back into estrogens' mechanism of action. Endocrinology 2011, 152:4481-4488.
    • (2011) Endocrinology , vol.152 , pp. 4481-4488
    • Koos, R.D.1
  • 35
    • 47049117155 scopus 로고    scopus 로고
    • P53 mutations in stromal fibroblasts sensitize tumors against chemotherapy
    • Lafkas D., Trimis G., Papavassiliou A.G., Kiaris H. P53 mutations in stromal fibroblasts sensitize tumors against chemotherapy. Int. J. Cancer 2008, 123:967-971.
    • (2008) Int. J. Cancer , vol.123 , pp. 967-971
    • Lafkas, D.1    Trimis, G.2    Papavassiliou, A.G.3    Kiaris, H.4
  • 36
    • 34247135913 scopus 로고    scopus 로고
    • Classical nuclear localization signals: definition, function, and interaction with importin α
    • Lange A., Mills R.E., Lange C.J., Stewart M., Devine S.E., Corbett A.H. Classical nuclear localization signals: definition, function, and interaction with importin α. J. Biol. Chem. 2007, 282:5101-5105.
    • (2007) J. Biol. Chem. , vol.282 , pp. 5101-5105
    • Lange, A.1    Mills, R.E.2    Lange, C.J.3    Stewart, M.4    Devine, S.E.5    Corbett, A.H.6
  • 38
    • 78650845707 scopus 로고    scopus 로고
    • G protein-coupled receptors: novel targets for drug discovery in cancer
    • Lappano R., Maggiolini M. G protein-coupled receptors: novel targets for drug discovery in cancer. Nat. Rev. Drug Discov. 2011, 10:47-60.
    • (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 47-60
    • Lappano, R.1    Maggiolini, M.2
  • 44
    • 67650456863 scopus 로고    scopus 로고
    • Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation
    • Lin B.C., Suzawa M., Blind R.D., Tobias S.C., Bulun S.E., Scanlan T.S., Ingraham H.A. Stimulating the GPR30 estrogen receptor with a novel tamoxifen analogue activates SF-1 and promotes endometrial cell proliferation. Cancer Res. 2009, 69:5415-5423.
    • (2009) Cancer Res. , vol.69 , pp. 5415-5423
    • Lin, B.C.1    Suzawa, M.2    Blind, R.D.3    Tobias, S.C.4    Bulun, S.E.5    Scanlan, T.S.6    Ingraham, H.A.7
  • 47
    • 63749125392 scopus 로고    scopus 로고
    • VEGFs and receptors involved in angiogenesis versus lymphangiogenesis
    • Lohela M., Bry M., Tammela T., Alitalo K. VEGFs and receptors involved in angiogenesis versus lymphangiogenesis. Curr. Opin. Cell Biol. 2009, 21:154-165.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 154-165
    • Lohela, M.1    Bry, M.2    Tammela, T.3    Alitalo, K.4
  • 48
    • 56749107194 scopus 로고    scopus 로고
    • The tumor microenvironment and its contribution to tumor evolution toward metastasis
    • Lorusso G., Ruegg C. The tumor microenvironment and its contribution to tumor evolution toward metastasis. Histochem. Cell Biol. 2008, 130:1091-1103.
    • (2008) Histochem. Cell Biol. , vol.130 , pp. 1091-1103
    • Lorusso, G.1    Ruegg, C.2
  • 49
    • 77955024164 scopus 로고    scopus 로고
    • Nuclear alternate estrogen receptor GPR30 mediates 17β-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts
    • Madeo A., Maggiolini M. Nuclear alternate estrogen receptor GPR30 mediates 17β-estradiol-induced gene expression and migration in breast cancer-associated fibroblasts. Cancer Res. 2010, 70:6036-6046.
    • (2010) Cancer Res. , vol.70 , pp. 6036-6046
    • Madeo, A.1    Maggiolini, M.2
  • 51
    • 0033062539 scopus 로고    scopus 로고
    • A non-radioactive method for inexpensive quantitative RT-PCR
    • Maggiolini M., Donzé O., Picard D. A non-radioactive method for inexpensive quantitative RT-PCR. Biol. Chem. 1999, 380:695-697.
    • (1999) Biol. Chem. , vol.380 , pp. 695-697
    • Maggiolini, M.1    Donzé, O.2    Picard, D.3
  • 52
    • 75149186664 scopus 로고    scopus 로고
    • The unfolding stories of GPR30, a new membrane bound estrogen receptor
    • Maggiolini M., Picard D. The unfolding stories of GPR30, a new membrane bound estrogen receptor. J. Endocrinol. 2009, 204:105-114.
    • (2009) J. Endocrinol. , vol.204 , pp. 105-114
    • Maggiolini, M.1    Picard, D.2
  • 56
    • 20844457958 scopus 로고    scopus 로고
    • Intracellular signaling of lipid mediators via cognate nuclear G protein-coupled receptors
    • Marrache A.M., Gobeil F., Zhu T., Chemtob S. Intracellular signaling of lipid mediators via cognate nuclear G protein-coupled receptors. Endothelium 2005, 12:63-72.
    • (2005) Endothelium , vol.12 , pp. 63-72
    • Marrache, A.M.1    Gobeil, F.2    Zhu, T.3    Chemtob, S.4
  • 58
    • 0346157370 scopus 로고    scopus 로고
    • Tumor-stroma interaction of human pancreatic cancer: acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins
    • Miyamoto H., Murakami T., Tsuchida K., Sugino H., Miyake H., Tashiro S. Tumor-stroma interaction of human pancreatic cancer: acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins. Pancreas 2004, 28:38-44.
    • (2004) Pancreas , vol.28 , pp. 38-44
    • Miyamoto, H.1    Murakami, T.2    Tsuchida, K.3    Sugino, H.4    Miyake, H.5    Tashiro, S.6
  • 61
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
    • Orimo A., Gupta P.B., Sgroi D.C., Arenzana-Seisdedos F., Delaunay T., Naeem R., Carey V.J., Richardson A.L., Weinberg R.A. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005, 121:335-348.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 62
    • 60949101225 scopus 로고    scopus 로고
    • Cancer-associated fibroblasts and tumor growth-bystanders turning into key players
    • Ostman A., Augsten M. Cancer-associated fibroblasts and tumor growth-bystanders turning into key players. Curr. Opin. Genet. Dev. 2009, 19:67-73.
    • (2009) Curr. Opin. Genet. Dev. , vol.19 , pp. 67-73
    • Ostman, A.1    Augsten, M.2
  • 64
    • 62049084027 scopus 로고    scopus 로고
    • Estrogenic GPR30 signaling induces proliferation and migration of breast cancer cells through CTGF
    • Pandey D.P., Lappano R., Albanito L., Madeo A., Maggiolini M., Picard D. Estrogenic GPR30 signaling induces proliferation and migration of breast cancer cells through CTGF. EMBO J. 2009, 28:523-532.
    • (2009) EMBO J. , vol.28 , pp. 523-532
    • Pandey, D.P.1    Lappano, R.2    Albanito, L.3    Madeo, A.4    Maggiolini, M.5    Picard, D.6
  • 65
    • 46349096631 scopus 로고    scopus 로고
    • Estrogen signaling characteristics of Atlantic croaker G protein-coupled receptor 30 (GPR30) and evidence it is involved in maintenance of oocyte meiotic arrest
    • Pang Y., Dong J., Thomas P. Estrogen signaling characteristics of Atlantic croaker G protein-coupled receptor 30 (GPR30) and evidence it is involved in maintenance of oocyte meiotic arrest. Endocrinology 2008, 149:3410-3426.
    • (2008) Endocrinology , vol.149 , pp. 3410-3426
    • Pang, Y.1    Dong, J.2    Thomas, P.3
  • 66
    • 0029851421 scopus 로고    scopus 로고
    • Effect of oestradiol and insulin on the proliferative pattern and on oestrogen and progesterone receptor contents in MCF-7 cells
    • Panno M.L., Salerno M., Pezzi V., Sisci D., Maggiolini M., Mauro L., Morrone E.G., Andò S. Effect of oestradiol and insulin on the proliferative pattern and on oestrogen and progesterone receptor contents in MCF-7 cells. J. Cancer Res. Clin. Oncol. 1996, 122:745-749.
    • (1996) J. Cancer Res. Clin. Oncol. , vol.122 , pp. 745-749
    • Panno, M.L.1    Salerno, M.2    Pezzi, V.3    Sisci, D.4    Maggiolini, M.5    Mauro, L.6    Morrone, E.G.7    Andò, S.8
  • 67
    • 67349105361 scopus 로고    scopus 로고
    • Mechanisms of estrogen signaling and gene expression via GPR30
    • Prossnitz E.R., Maggiolini M. Mechanisms of estrogen signaling and gene expression via GPR30. Mol. Cell. Endocrinol. 2009, 308:32-38.
    • (2009) Mol. Cell. Endocrinol. , vol.308 , pp. 32-38
    • Prossnitz, E.R.1    Maggiolini, M.2
  • 68
  • 69
    • 80053508375 scopus 로고    scopus 로고
    • Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes
    • Rago V., Romeo F., Giordano F., Maggiolini M., Carpino A. Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes. Reprod. Biol. Endocrinol. 2011, 9:135.
    • (2011) Reprod. Biol. Endocrinol. , vol.9 , pp. 135
    • Rago, V.1    Romeo, F.2    Giordano, F.3    Maggiolini, M.4    Carpino, A.5
  • 70
    • 79953227087 scopus 로고    scopus 로고
    • The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytes
    • Recchia A.G., De Francesco E.M., Vivacqua A., Sisc i D., Panno M.L., Andò S., Maggiolini M. The G protein-coupled receptor 30 is up-regulated by hypoxia-inducible factor-1alpha (HIF-1alpha) in breast cancer cells and cardiomyocytes. J. Biol. Chem. 2011, 286:10773-10782.
    • (2011) J. Biol. Chem. , vol.286 , pp. 10773-10782
    • Recchia, A.G.1    De Francesco, E.M.2    Vivacqua, A.3    Sisc, I.D.4    Panno, M.L.5    Andò, S.6    Maggiolini, M.7
  • 71
    • 14844343093 scopus 로고    scopus 로고
    • A transmembrane intracellular estrogen receptor mediates rapid cell signaling
    • Revankar C.M., Cimino D.F., Sklar L.A., Arterburn J.B., Prossnitz E.R. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 2005, 307:1625-1630.
    • (2005) Science , vol.307 , pp. 1625-1630
    • Revankar, C.M.1    Cimino, D.F.2    Sklar, L.A.3    Arterburn, J.B.4    Prossnitz, E.R.5
  • 74
    • 36348947509 scopus 로고    scopus 로고
    • Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei
    • Sakamoto H., Matsuda K., Hosokawa K., Nishi M., Morris J.F., Prossnitz E.R., Kawata M. Expression of G protein-coupled receptor-30, a G protein-coupled membrane estrogen receptor, in oxytocin neurons of the rat paraventricular and supraoptic nuclei. Endocrinology 2007, 148:5842-5850.
    • (2007) Endocrinology , vol.148 , pp. 5842-5850
    • Sakamoto, H.1    Matsuda, K.2    Hosokawa, K.3    Nishi, M.4    Morris, J.F.5    Prossnitz, E.R.6    Kawata, M.7
  • 76
    • 53249101612 scopus 로고    scopus 로고
    • The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line
    • Sirianni R., Chimento A., Ruggiero C., De Luca A., Lappano R., Andò S., Maggiolini M., Pezzi V. The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17beta-estradiol on mouse spermatogonial GC-1 cell line. Endocrinology 2008, 149:5043-5051.
    • (2008) Endocrinology , vol.149 , pp. 5043-5051
    • Sirianni, R.1    Chimento, A.2    Ruggiero, C.3    De Luca, A.4    Lappano, R.5    Andò, S.6    Maggiolini, M.7    Pezzi, V.8
  • 79
    • 0142121425 scopus 로고    scopus 로고
    • Translocation of beta-catenin into the nucleus independent of interactions with FG-rich nucleoporins
    • Suh E.K., Gumbiner B.M. Translocation of beta-catenin into the nucleus independent of interactions with FG-rich nucleoporins. Exp. Cell Res. 2003, 290:447-456.
    • (2003) Exp. Cell Res. , vol.290 , pp. 447-456
    • Suh, E.K.1    Gumbiner, B.M.2
  • 80
    • 12344307170 scopus 로고    scopus 로고
    • Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells
    • Thomas P., Pang Y., Filardo E.J., Dong J. Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 2005, 146:624-632.
    • (2005) Endocrinology , vol.146 , pp. 624-632
    • Thomas, P.1    Pang, Y.2    Filardo, E.J.3    Dong, J.4
  • 81
    • 0035253742 scopus 로고    scopus 로고
    • Know thy neighbor: stromal cells can contribute oncogenic signals
    • Tlsty T.D., Hein P.W. Know thy neighbor: stromal cells can contribute oncogenic signals. Curr. Opin. Genet. Dev. 2001, 11:54-59.
    • (2001) Curr. Opin. Genet. Dev. , vol.11 , pp. 54-59
    • Tlsty, T.D.1    Hein, P.W.2
  • 83
    • 33344461590 scopus 로고    scopus 로고
    • The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17β-estradiol and hydroxytamoxifen in endometrial cancer cells
    • Vivacqua A., Bonofiglio D., Recchia A.G., Musti A.M., Picard D., Andò S., Maggiolini M. The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17β-estradiol and hydroxytamoxifen in endometrial cancer cells. Mol. Endocrinol. 2006, 20:631-646.
    • (2006) Mol. Endocrinol. , vol.20 , pp. 631-646
    • Vivacqua, A.1    Bonofiglio, D.2    Recchia, A.G.3    Musti, A.M.4    Picard, D.5    Andò, S.6    Maggiolini, M.7
  • 85
    • 84863724924 scopus 로고    scopus 로고
    • GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells
    • Vivacqua A., Romeo E., De Marco P., De Francesco E.M., Abonante S., Maggiolini M. GPER mediates the Egr-1 expression induced by 17β-estradiol and 4-hydroxitamoxifen in breast and endometrial cancer cells. Breast Cancer Res. Treat. 2012, 133:1025-1035.
    • (2012) Breast Cancer Res. Treat. , vol.133 , pp. 1025-1035
    • Vivacqua, A.1    Romeo, E.2    De Marco, P.3    De Francesco, E.M.4    Abonante, S.5    Maggiolini, M.6
  • 86
    • 50449104180 scopus 로고    scopus 로고
    • G protein-coupled receptor 30 expression is required for estrogen stimulation of primordial follicle formation in the hamster ovary
    • Wang C., Prossnitz E.R., Roy S.K. G protein-coupled receptor 30 expression is required for estrogen stimulation of primordial follicle formation in the hamster ovary. Endocrinology 2008, 149:4452-4461.
    • (2008) Endocrinology , vol.149 , pp. 4452-4461
    • Wang, C.1    Prossnitz, E.R.2    Roy, S.K.3
  • 87
    • 77954759289 scopus 로고    scopus 로고
    • Nuclear trafficking of the epidermal growth factor receptor family membrane proteins
    • Wang Y.N., Yamaguchi H., Hsu J.M., Hung M.C. Nuclear trafficking of the epidermal growth factor receptor family membrane proteins. Oncogene 2010, 29:3997-4006.
    • (2010) Oncogene , vol.29 , pp. 3997-4006
    • Wang, Y.N.1    Yamaguchi, H.2    Hsu, J.M.3    Hung, M.C.4
  • 88
    • 0033974978 scopus 로고    scopus 로고
    • Nuclear localization of the type 1 parathyroid hormone/parathyroid hormone-related peptide receptor in MC3T3-E1 cells: association with serum-induced cell proliferation
    • Watson P.H., Fraher L.J., Natale B.V., Kisiel M., Hendy G.N., Hodsman A.B. Nuclear localization of the type 1 parathyroid hormone/parathyroid hormone-related peptide receptor in MC3T3-E1 cells: association with serum-induced cell proliferation. Bone 2000, 26:221-225.
    • (2000) Bone , vol.26 , pp. 221-225
    • Watson, P.H.1    Fraher, L.J.2    Natale, B.V.3    Kisiel, M.4    Hendy, G.N.5    Hodsman, A.B.6
  • 89
    • 0033848917 scopus 로고    scopus 로고
    • Nuclear and cytoskeletal translocation and localization of heterotrimeric G-proteins
    • Willard F.S., Crouch M.F. Nuclear and cytoskeletal translocation and localization of heterotrimeric G-proteins. Immunol. Cell Biol. 2000, 78:387-394.
    • (2000) Immunol. Cell Biol. , vol.78 , pp. 387-394
    • Willard, F.S.1    Crouch, M.F.2
  • 90
    • 77951233373 scopus 로고    scopus 로고
    • Cancer associated fibroblasts (CAFs) in tumor microenvironment
    • Xing F., Saidou J., Watabe K. Cancer associated fibroblasts (CAFs) in tumor microenvironment. Front Biosci. 2010, 15:166-179.
    • (2010) Front Biosci. , vol.15 , pp. 166-179
    • Xing, F.1    Saidou, J.2    Watabe, K.3
  • 91
    • 62549090621 scopus 로고    scopus 로고
    • Estrogen-related cancer microenvironment of breast carcinoma
    • Yamaguchi Y., Hayashi S. Estrogen-related cancer microenvironment of breast carcinoma. Endocr. J. 2009, 56:1-7.
    • (2009) Endocr. J. , vol.56 , pp. 1-7
    • Yamaguchi, Y.1    Hayashi, S.2


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