Eps8 controls dendritic spine density and synaptic plasticity through its actin-capping activity

EMBO Journal

Volumn 32, Issue 12, 2013, Pages 1730-1744

  Menna, Elisabetta ^a,b   Zambetti, Stefania ^a   Morini, Raffaella ^a,b   Donzelli, Andrea ^a   Disanza, Andrea ^c   Calvigioni, Daniela ^a   Braida, Daniela ^a   Nicolini, Chiara ^d   Orlando, Marta ^a   Fossati, Giuliana ^a,b   Cristina Regondi, Maria ^e   Pattini, Linda ^f   Frassoni, Carolina ^e   Francolini, Maura ^a   Scita, Giorgio ^c   Sala, Mariaelvina ^a   Fahnestock, Margaret ^d   Matteoli, Michela ^a,b  

^a UNIVERSITY OF MILAN   (Italy)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^c FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^d MCMASTER UNIVERSITY   (Canada)

^e DEPARTMENT OF NEUROSURGERY   (Italy)

^f POLITECNICO DI MILANO   (Italy)

Author keywords

actin capping activity; activity dependent plasticity; Eps8; learning and memory defects; spine morphogenesis

Indexed keywords

ACTIN CAPPING PROTEIN; EPS8 PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; UNCLASSIFIED DRUG;

ACTIN CAPPING; ARTICLE; AUTISM; COGNITION; DENDRITIC SPINE; DISEASE ASSOCIATION; HIPPOCAMPUS; HUMAN; IN VIVO STUDY; INTELLECTUAL IMPAIRMENT; LEARNING DISORDER; LONG TERM POTENTIATION; MEMORY DISORDER; NERVE CELL PLASTICITY; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; WILD TYPE;

ACTINS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; AUTISTIC DISORDER; BRAIN; COGNITION; DENDRITIC SPINES; HUMANS; LONG-TERM POTENTIATION; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; SYNAPSES;

MUS;

EID: 84879462883     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2013.107     Document Type: Article

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