Eps8 regulates hair bundle length and functional maturation of mammalian auditory hair cells

PLoS Biology

Volumn 9, Issue 4, 2011, Pages

  Zampini, Valeria ^a,b   Rüttiger, Lukas ^c   Johnson, Stuart L ^a   Franz, Christoph ^c   Furness, David N ^d   Waldhaus, Jörg ^c   Xiong, Hao ^c,e   Hackney, Carole M ^a   Holley, Matthew C ^a   Offenhauser, Nina ^f   Fiore, Pier Paolo ^f,g,h   Knipper, Marlies ^c   Masetto, Sergio ^b   Marcotti, Walter ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF PAVIA   (Italy)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d KEELE UNIVERSITY   (United Kingdom)

^e HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^f FIRC INSTITUTE OF MOLECULAR ONCOLOGY   (Italy)

^g EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^h UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CALCIUM ION; EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE 8; POTASSIUM CHANNEL KCNQ4; PROTEIN EPS8; REGULATOR PROTEIN; UNCLASSIFIED DRUG; CALCIUM; CALCIUM CHANNEL; CYTOSKELETON PROTEIN; EPS8 PROTEIN, MOUSE; POTASSIUM CHANNEL; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY HAIR BUNDLE; AUDITORY HAIR BUNDLE HEIGHT; AUDITORY HAIR BUNDLE MORPHOLOGY; BASOLATERAL MEMBRANE; CALCIUM TRANSPORT; CELL MATURATION; CELL MEMBRANE CAPACITANCE; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE POTENTIAL; CELL MEMBRANE STEADY POTENTIAL; COCHLEA POTENTIAL; CONTROLLED STUDY; DISTORTION PRODUCT OTOACOUSTIC EMISSION; ELECTROCOCHLEOGRAPHY; EVOKED BRAIN STEM AUDITORY RESPONSE; EXOCYTOSIS; EXTRACELLULAR CALCIUM; HAIR CELL; HEARING LOSS; INNER HAIR CELL; KNOCKOUT MOUSE; MECHANO ELECTRICAL TRANSDUCTION; MEMBRANE ELECTROPHYSIOLOGY; MOUSE; NONHUMAN; OUTER HAIR CELL; POTASSIUM CURRENT; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PURE TONE AUDIOMETRY; SENSORY RECEPTOR; STEREOCILIUM; ACTION POTENTIAL; ANIMAL; AUDITORY STIMULATION; C57BL MOUSE; CELL SURFACE; COCHLEA; CYTOLOGY; GENE DELETION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEARING IMPAIRMENT; MECHANOTRANSDUCTION; METABOLISM; MOUSE MUTANT; PHYSIOLOGY; ULTRASTRUCTURE;

MAMMALIA; MUS;

ACOUSTIC STIMULATION; ACTION POTENTIALS; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CALCIUM; CALCIUM CHANNELS; CELL SURFACE EXTENSIONS; COCHLEA; CYTOSKELETAL PROTEINS; DEAFNESS; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; EXOCYTOSIS; GENE DELETION; HAIR CELLS, AUDITORY; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; POTASSIUM CHANNELS;

EID: 79955488611     PISSN: 15449173     EISSN: 15457885     Source Type: Journal    
DOI: 10.1371/journal.pbio.1001048     Document Type: Article

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