-
1
-
-
19044393872
-
Adipose tissue, inflammation, and cardiovascular disease
-
Berg AH, Scherer PE (2005) Adipose tissue, inflammation, and cardiovascular disease. Circ Res 96: 939-949.
-
(2005)
Circ Res
, vol.96
, pp. 939-949
-
-
Berg, A.H.1
Scherer, P.E.2
-
2
-
-
11144265737
-
The new concept of adipose tissue function
-
Hauner H (2004) The new concept of adipose tissue function. Physiol Behav 83: 653-658.
-
(2004)
Physiol Behav
, vol.83
, pp. 653-658
-
-
Hauner, H.1
-
3
-
-
33750684953
-
Role of insulin, adipocyte hormones, and nutrient-sensing pathways in regulating fuel metabolism and energy homeostasis: A nutritional perspective of diabetes, obesity, and cancer
-
Marshall S (2006) Role of insulin, adipocyte hormones, and nutrient-sensing pathways in regulating fuel metabolism and energy homeostasis: a nutritional perspective of diabetes, obesity, and cancer. Sci STKE 2006: re7.
-
(2006)
Sci STKE 2006
-
-
Marshall, S.1
-
4
-
-
0036068133
-
Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance
-
Bluher M, Michael MD, Peroni OD, Ueki K, Carter N, et al. (2002) Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance. Dev Cell 3: 25-38.
-
(2002)
Dev Cell
, vol.3
, pp. 25-38
-
-
Bluher, M.1
Michael, M.D.2
Peroni, O.D.3
Ueki, K.4
Carter, N.5
-
5
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
Bluher M, Kahn BB, Kahn CR (2003) Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299: 572-574.
-
(2003)
Science
, vol.299
, pp. 572-574
-
-
Bluher, M.1
Kahn, B.B.2
Kahn, C.R.3
-
6
-
-
13944253348
-
Calorie restriction-the SIR2 connection
-
Guarente L, Picard F (2005) Calorie restriction-the SIR2 connection. Cell 120: 473-482.
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
7
-
-
0022517746
-
The retardation of aging in mice by dietary restriction: Longevity, cancer, immunity and lifetime energy intake
-
Weindruch R, Walford RL, Fligiel S, Guthrie D (1986) The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J Nutr 116: 641-654.
-
(1986)
J Nutr
, vol.116
, pp. 641-654
-
-
Weindruch, R.1
Walford, R.L.2
Fligiel, S.3
Guthrie, D.4
-
8
-
-
33749047668
-
Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics
-
Offenhauser N, Castelletti D, Mapelli L, Soppo BE, Regondi MC, et al. (2006) Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Cell 127: 213-226.
-
(2006)
Cell
, vol.127
, pp. 213-226
-
-
Offenhauser, N.1
Castelletti, D.2
Mapelli, L.3
Soppo, B.E.4
Regondi, M.C.5
-
9
-
-
0033575885
-
-
Scita G, Nordstrom J, Carbone R, Tenca P, Giardina G, et al. (1999) EPS8 and E3B1 transduce signals from Ras to Rac. Nature 401: 290-293.
-
Scita G, Nordstrom J, Carbone R, Tenca P, Giardina G, et al. (1999) EPS8 and E3B1 transduce signals from Ras to Rac. Nature 401: 290-293.
-
-
-
-
10
-
-
10344222932
-
A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans
-
Croce A, Cassata G, Disanza A, Gagliani MC, Tacchetti C, et al. (2004) A novel actin barbed-end-capping activity in EPS-8 regulates apical morphogenesis in intestinal cells of Caenorhabditis elegans. Nat Cell Biol 6: 1173-1179.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1173-1179
-
-
Croce, A.1
Cassata, G.2
Disanza, A.3
Gagliani, M.C.4
Tacchetti, C.5
-
11
-
-
10344251483
-
Eps8 controls actin-based motility by capping the barbed ends of actin filaments
-
Disanza A, Carlier MF, Stradal TE, Didry D, Frittoli E, et al. (2004) Eps8 controls actin-based motility by capping the barbed ends of actin filaments. Nat Cell Biol 6: 1180-1188.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1180-1188
-
-
Disanza, A.1
Carlier, M.F.2
Stradal, T.E.3
Didry, D.4
Frittoli, E.5
-
12
-
-
33751543109
-
Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex
-
Disanza A, Mantoani S, Hertzog M, Gerboth S, Frittoli E, et al. (2006) Regulation of cell shape by Cdc42 is mediated by the synergic actin-bundling activity of the Eps8-IRSp53 complex. Nat Cell Biol 8: 1337-1347.
-
(2006)
Nat Cell Biol
, vol.8
, pp. 1337-1347
-
-
Disanza, A.1
Mantoani, S.2
Hertzog, M.3
Gerboth, S.4
Frittoli, E.5
-
13
-
-
0035802118
-
An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine
-
Scita G, Tenca P, Areces LB, Tocchetti A, Frittoli E, et al. (2001) An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine. J Cell Biol 154: 1031-1044.
-
(2001)
J Cell Biol
, vol.154
, pp. 1031-1044
-
-
Scita, G.1
Tenca, P.2
Areces, L.B.3
Tocchetti, A.4
Frittoli, E.5
-
14
-
-
0037421209
-
Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1
-
Innocenti M, Frittoli E, Ponzanelli I, Falck JR, Brachmann SM, et al. (2003) Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1. J Cell Biol 160: 17-23.
-
(2003)
J Cell Biol
, vol.160
, pp. 17-23
-
-
Innocenti, M.1
Frittoli, E.2
Ponzanelli, I.3
Falck, J.R.4
Brachmann, S.M.5
-
15
-
-
34848816785
-
Effect of long-term caloric restriction on oxygen consumption and body temperature in two different strains of mice
-
Ferguson M, Sohal BH, Forster MJ, Sohal RS (2007) Effect of long-term caloric restriction on oxygen consumption and body temperature in two different strains of mice. Mech Ageing Dev 128: 539-545.
-
(2007)
Mech Ageing Dev
, vol.128
, pp. 539-545
-
-
Ferguson, M.1
Sohal, B.H.2
Forster, M.J.3
Sohal, R.S.4
-
16
-
-
18944391216
-
Energy expenditure of calorically restricted rats is higher than predicted from their altered body composition
-
Selman C, Phillips T, Staib JL, Duncan JS, Leeuwenburgh C, et al. (2005) Energy expenditure of calorically restricted rats is higher than predicted from their altered body composition. Mech Ageing Dev 126: 783-793.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 783-793
-
-
Selman, C.1
Phillips, T.2
Staib, J.L.3
Duncan, J.S.4
Leeuwenburgh, C.5
-
17
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
Kahn SE, Hull RL, Utzschneider KM (2006) Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444: 840-846.
-
(2006)
Nature
, vol.444
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
18
-
-
33845914986
-
Mechanisms linking obesity with cardiovascular disease
-
Van Gaal LF, Mertens IL, De Block CE (2006) Mechanisms linking obesity with cardiovascular disease. Nature 444: 875-880.
-
(2006)
Nature
, vol.444
, pp. 875-880
-
-
Van Gaal, L.F.1
Mertens, I.L.2
De Block, C.E.3
-
19
-
-
28844469898
-
Increase in activity during calorie restriction requires Sirt1
-
Chen D, Steele AD, Lindquist S, Guarente L (2005) Increase in activity during calorie restriction requires Sirt1. Science 310: 1641.
-
(2005)
Science
, vol.310
, pp. 1641
-
-
Chen, D.1
Steele, A.D.2
Lindquist, S.3
Guarente, L.4
-
20
-
-
0038064168
-
Strain variation in the response of body temperature to dietary restriction
-
Rikke BA, Yerg JE 3rd, Battaglia ME, Nagy TR, Allison DB, et al. (2003) Strain variation in the response of body temperature to dietary restriction. Mech Ageing Dev 124: 663-678.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 663-678
-
-
Rikke, B.A.1
Yerg 3rd, J.E.2
Battaglia, M.E.3
Nagy, T.R.4
Allison, D.B.5
-
21
-
-
1842732174
-
Temporal linkage between the phenotypic and genomic responses to caloric restriction
-
Dhahbi JM, Kim HJ, Mote PL, Beaver RJ, Spindler SR (2004) Temporal linkage between the phenotypic and genomic responses to caloric restriction. Proc Natl Acad Sci U S A 101: 5524-5529.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 5524-5529
-
-
Dhahbi, J.M.1
Kim, H.J.2
Mote, P.L.3
Beaver, R.J.4
Spindler, S.R.5
-
22
-
-
44649131231
-
Genome-wide effects of acute progressive feed restriction in liver and white adipose tissue
-
Pohjanvirta R, Boutros PC, Moffat ID, Linden J, Wendelin D, et al. (2008) Genome-wide effects of acute progressive feed restriction in liver and white adipose tissue. Toxicol Appl Pharmacol 230: 41-56.
-
(2008)
Toxicol Appl Pharmacol
, vol.230
, pp. 41-56
-
-
Pohjanvirta, R.1
Boutros, P.C.2
Moffat, I.D.3
Linden, J.4
Wendelin, D.5
-
23
-
-
3843070757
-
Starvation response in mouse liver shows strong correlation with life-span-prolonging processes
-
Bauer M, Hamm AC, Bonaus M, Jacop A, Jaekel J, et al. (2004) Starvation response in mouse liver shows strong correlation with life-span-prolonging processes. Physiol Genomics 17: 230-244.
-
(2004)
Physiol Genomics
, vol.17
, pp. 230-244
-
-
Bauer, M.1
Hamm, A.C.2
Bonaus, M.3
Jacop, A.4
Jaekel, J.5
-
24
-
-
0347360339
-
The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway
-
Offenhäuser N, Borgonovo A, Disanza A, Romano P, Ponzanelli I, et al. (2004) The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway. Mol Biol Cell 15: 91-98.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 91-98
-
-
Offenhäuser, N.1
Borgonovo, A.2
Disanza, A.3
Romano, P.4
Ponzanelli, I.5
-
26
-
-
33644890148
-
Sos-mediated activation of rac1 by p66shc
-
Khanday FA, Santhanam L, Kasuno K, Yamamori T, Naqvi A, et al. (2006) Sos-mediated activation of rac1 by p66shc. J Cell Biol 172: 817-822.
-
(2006)
J Cell Biol
, vol.172
, pp. 817-822
-
-
Khanday, F.A.1
Santhanam, L.2
Kasuno, K.3
Yamamori, T.4
Naqvi, A.5
-
27
-
-
0036218579
-
MYO1A (brush border myosin I) dynamics in the brush border of LLC-PK1-CL4 cells
-
Tyska MJ, Mooseker MS (2002) MYO1A (brush border myosin I) dynamics in the brush border of LLC-PK1-CL4 cells. Biophys J 82: 1869-1883.
-
(2002)
Biophys J
, vol.82
, pp. 1869-1883
-
-
Tyska, M.J.1
Mooseker, M.S.2
-
28
-
-
67649935286
-
-
Menna E, Disanza A, Cagnoli C, Schenk U, Gelsomino G, et al. (2009) Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). PLoS Biol 7: e1000138.
-
Menna E, Disanza A, Cagnoli C, Schenk U, Gelsomino G, et al. (2009) Eps8 regulates axonal filopodia in hippocampal neurons in response to brain-derived neurotrophic factor (BDNF). PLoS Biol 7: e1000138.
-
-
-
-
29
-
-
77949670332
-
-
submitted
-
Hertzog M, Milanesi M, Hazelwood L, Disanza A, Liu H, et al. (2009) The deadly embrace of EPS8 at the growing end of actin filaments (submitted).
-
(2009)
The deadly embrace of EPS8 at the growing end of actin filaments
-
-
Hertzog, M.1
Milanesi, M.2
Hazelwood, L.3
Disanza, A.4
Liu, H.5
-
30
-
-
0028587210
-
Functional differences between L- and T-plastin isoforms
-
Arpin M, Friederich E, Algrain M, Vernel F, Louvard D (1994) Functional differences between L- and T-plastin isoforms. J Cell Biol 127: 1995-2008.
-
(1994)
J Cell Biol
, vol.127
, pp. 1995-2008
-
-
Arpin, M.1
Friederich, E.2
Algrain, M.3
Vernel, F.4
Louvard, D.5
-
31
-
-
0028821179
-
Suppression of villin expression by antisense RNA impairs brush border assembly in polarized epithelial intestinal cells
-
Costa de Beauregard MA, Pringault E, Robine S, Louvard D (1995) Suppression of villin expression by antisense RNA impairs brush border assembly in polarized epithelial intestinal cells. EMBO J 14: 409-421.
-
(1995)
EMBO J
, vol.14
, pp. 409-421
-
-
Costa de Beauregard, M.A.1
Pringault, E.2
Robine, S.3
Louvard, D.4
-
32
-
-
0346849715
-
Espin cross-links cause the elongation of microvillus-type parallel actin bundles in vivo
-
Loomis PA, Zheng L, Sekerkova G, Changyaleket B, Mugnaini E, et al. (2003) Espin cross-links cause the elongation of microvillus-type parallel actin bundles in vivo. J Cell Biol 163: 1045-1055.
-
(2003)
J Cell Biol
, vol.163
, pp. 1045-1055
-
-
Loomis, P.A.1
Zheng, L.2
Sekerkova, G.3
Changyaleket, B.4
Mugnaini, E.5
-
33
-
-
66249098897
-
Plastin 1 binds to keratin and is required for terminal web assembly in the intestinal epithelium
-
Grimm-Gunter EM, Revenu C, Ramos S, Hurbain I, Smyth N, et al. (2009) Plastin 1 binds to keratin and is required for terminal web assembly in the intestinal epithelium. Mol Biol Cell 20: 2549-2562.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 2549-2562
-
-
Grimm-Gunter, E.M.1
Revenu, C.2
Ramos, S.3
Hurbain, I.4
Smyth, N.5
-
34
-
-
33748931457
-
Central nervous system control of food intake and body weight
-
Morton GJ, Cummings DE, Baskin DG, Barsh GS, Schwartz MW (2006) Central nervous system control of food intake and body weight. Nature 443: 289-295.
-
(2006)
Nature
, vol.443
, pp. 289-295
-
-
Morton, G.J.1
Cummings, D.E.2
Baskin, D.G.3
Barsh, G.S.4
Schwartz, M.W.5
-
35
-
-
33845875966
-
Gut hormones and the regulation of energy homeostasis
-
Murphy KG, Bloom SR (2006) Gut hormones and the regulation of energy homeostasis. Nature 444: 854-859.
-
(2006)
Nature
, vol.444
, pp. 854-859
-
-
Murphy, K.G.1
Bloom, S.R.2
-
36
-
-
0032879458
-
Controlling caloric consumption: Protocols for rodents and rhesus monkeys
-
Pugh TD, Klopp RG, Weindruch R (1999) Controlling caloric consumption: protocols for rodents and rhesus monkeys. Neurobiol Aging 20: 157-165.
-
(1999)
Neurobiol Aging
, vol.20
, pp. 157-165
-
-
Pugh, T.D.1
Klopp, R.G.2
Weindruch, R.3
-
37
-
-
2942527528
-
Liquid chromatographic-mass spectrometric method to assess cytochrome P450-mediated metabolism of testosterone by rat everted gut sacs
-
Arellano C, Philibert C, Lacombe O, Woodley J, Houin G (2004) Liquid chromatographic-mass spectrometric method to assess cytochrome P450-mediated metabolism of testosterone by rat everted gut sacs. J Chromatogr B Analyt Technol Biomed Life Sci 807: 263-270.
-
(2004)
J Chromatogr B Analyt Technol Biomed Life Sci
, vol.807
, pp. 263-270
-
-
Arellano, C.1
Philibert, C.2
Lacombe, O.3
Woodley, J.4
Houin, G.5
-
38
-
-
34447519003
-
The Rab8 GTPase regulates apical protein localization in intestinal cells
-
Sato T, Mushiake S, Kato Y, Sato K, Sato M, et al. (2007) The Rab8 GTPase regulates apical protein localization in intestinal cells. Nature 448: 366-369.
-
(2007)
Nature
, vol.448
, pp. 366-369
-
-
Sato, T.1
Mushiake, S.2
Kato, Y.3
Sato, K.4
Sato, M.5
-
39
-
-
33748427104
-
Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice
-
Duivenvoorden I, Voshol PJ, Rensen PC, van Duyvenvoorde W, Romijn JA, et al. (2006) Dietary sphingolipids lower plasma cholesterol and triacylglycerol and prevent liver steatosis in APOE*3Leiden mice. Am J Clin Nutr 84: 312-321.
-
(2006)
Am J Clin Nutr
, vol.84
, pp. 312-321
-
-
Duivenvoorden, I.1
Voshol, P.J.2
Rensen, P.C.3
van Duyvenvoorde, W.4
Romijn, J.A.5
-
40
-
-
34250378697
-
Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans
-
An G, Wei B, Xia B, McDaniel JM, Ju T, et al. (2007) Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans. J Exp Med 204: 1417-1429.
-
(2007)
J Exp Med
, vol.204
, pp. 1417-1429
-
-
An, G.1
Wei, B.2
Xia, B.3
McDaniel, J.M.4
Ju, T.5
-
41
-
-
34250653301
-
Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase
-
Friebe A, Mergia E, Dangel O, Lange A, Koesling D (2007) Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase. Proc Natl Acad Sci U S A 104: 7699-7704.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 7699-7704
-
-
Friebe, A.1
Mergia, E.2
Dangel, O.3
Lange, A.4
Koesling, D.5
-
42
-
-
41549157255
-
Systematic gene expression profiling of mouse model series reveals coexpressed genes
-
Horsch M, Schadler S, Gailus-Durner V, Fuchs H, Meyer H, et al. (2008) Systematic gene expression profiling of mouse model series reveals coexpressed genes. Proteomics 8: 1248-1256.
-
(2008)
Proteomics
, vol.8
, pp. 1248-1256
-
-
Horsch, M.1
Schadler, S.2
Gailus-Durner, V.3
Fuchs, H.4
Meyer, H.5
-
44
-
-
0037311919
-
TM4: A free, open-source system for microarray data management and analysis
-
Saeed AI, Sharov V, White J, Li J, Liang W, et al. (2003) TM4: a free, open-source system for microarray data management and analysis. Biotechniques 34: 374-378.
-
(2003)
Biotechniques
, vol.34
, pp. 374-378
-
-
Saeed, A.I.1
Sharov, V.2
White, J.3
Li, J.4
Liang, W.5
-
45
-
-
0036898577
-
Microarray data normalization and transformation
-
Quackenbush J (2002) Microarray data normalization and transformation. Nat Genet 32 Suppl: 496-501.
-
(2002)
Nat Genet
, vol.32
, Issue.SUPPL.
, pp. 496-501
-
-
Quackenbush, J.1
-
46
-
-
0035942271
-
Significance analysis of microarrays applied to the ionizing radiation response
-
Tusher VG, Tibshirani R, Chu G (2001) Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98: 5116-5121.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5116-5121
-
-
Tusher, V.G.1
Tibshirani, R.2
Chu, G.3
-
47
-
-
1342294092
-
Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation
-
Yang YH (2002) Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res 30: e15.
-
(2002)
Nucleic Acids Res
, vol.30
-
-
Yang, Y.H.1
-
48
-
-
0033581704
-
The p66shc adaptor protein controls oxidative stress response and life span in mammals
-
Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi P, et al. (1999) The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature 402: 309-313.
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
Pelicci, G.4
Reboldi, P.5
|