Pharmacologic rescue of impaired cognitive flexibility, social deficits, increased aggression, and seizure susceptibility in oxytocin receptor null mice: A neurobehavioral model of autism

Biological Psychiatry

Volumn 69, Issue 9, 2011, Pages 875-882

  Sala, Mariaelvina ^a   Braida, Daniela ^a   Lentini, Daniela ^b   Busnelli, Marta ^a,c   Bulgheroni, Elisabetta ^c   Capurro, Valeria ^a   Finardi, Annamaria ^a   Donzelli, Andrea ^a   Pattini, Linda ^d   Rubino, Tiziana ^e   Parolaro, Daniela ^e   Nishimori, Katsuhiko ^f   Parenti, Marco ^b   Chini, Bice ^c  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

^c CNR   (Italy)

^d POLITECNICO DI MILANO   (Italy)

^e UNIVERSITY OF INSUBRIA   (Italy)

^f TOHOKU UNIVERSITY   (Japan)

Author keywords

Animal model; autism spectrum disorders; cognitive flexibility; oxytocin; seizures; vasopressin

Indexed keywords

4 AMINOBUTYRIC ACID; OXYTOCIN; OXYTOCIN RECEPTOR; PENTETRAZOLE; RELCOVAPTAN; VASOPRESSIN; VASOPRESSIN RECEPTOR;

AGGRESSION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTISM; AUTORADIOGRAPHY; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE PREDISPOSITION; HIPPOCAMPUS; LEARNING; MALE; MOUSE; MOUSE EMBRYO; MYOCLONUS SEIZURE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SOCIAL BEHAVIOR; SOCIAL DISABILITY;

AGGRESSION; ANALYSIS OF VARIANCE; ANIMALS; ARGININE VASOPRESSIN; AUTISTIC DISORDER; AUTORADIOGRAPHY; CELLS, CULTURED; COGNITION; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, KNOCKOUT; NEURONS; OXYTOCIN; RECEPTORS, OXYTOCIN; SEIZURES; SOCIAL BEHAVIOR;

EID: 79954594363     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2010.12.022     Document Type: Article

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