Exogenous heparin binds and inhibits bone morphogenetic protein 6 biological activity

International Orthopaedics

Volumn 37, Issue 3, 2013, Pages 529-541

  Brkljacic, Jelena ^a   Pauk, Martina ^a   Erjavec, Igor ^a   Cipcic, Antonio ^a   Grgurevic, Lovorka ^a   Zadro, Renata ^b   Inman, Gareth J ^c   Vukicevic, Slobodan ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b KBC Zagreb   (Croatia)

^c UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 6; HEPARIN; OSTEOCALCIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; ANTICOAGULANT AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BLOOD CLOTTING; BONE DENSITY; CONTROLLED STUDY; DRUG PROTEIN BINDING; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; BONE DEVELOPMENT; CELL LINE; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; ANTICOAGULANTS; BONE MORPHOGENETIC PROTEIN 6; CELL LINE; DISEASE MODELS, ANIMAL; HEPARIN; MICE; OSTEOGENESIS; OSTEOPOROSIS; RATS; RATS, SPRAGUE-DAWLEY;

MLCS; MLOWN;

EID: 84879457885     PISSN: 03412695     EISSN: 14325195     Source Type: Journal    
DOI: 10.1007/s00264-012-1714-3     Document Type: Article

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