메뉴 건너뛰기




Volumn 122, Issue 3, 2008, Pages 293-298

The effects of heparin and low molecular weight heparins on bone

Author keywords

Bone; Heparin; Low molecular weight heparin; Osteoporosis

Indexed keywords

DALTEPARIN; ENOXAPARIN; FONDAPARINUX; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN; NADROPARIN; TINZAPARIN;

EID: 45849107647     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2006.10.025     Document Type: Review
Times cited : (123)

References (36)
  • 1
    • 0035125405 scopus 로고    scopus 로고
    • Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety
    • Hirsh J., Warkentin T.E., Shaughnessy S.G., Anand S.S., Halperin H.L., Raschke R., et al. Heparin and low-molecular-weight heparin: mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety. Chest 119 S1 (2001) S64-S94
    • (2001) Chest , vol.119 , Issue.SUPPL.1
    • Hirsh, J.1    Warkentin, T.E.2    Shaughnessy, S.G.3    Anand, S.S.4    Halperin, H.L.5    Raschke, R.6
  • 4
    • 9544243083 scopus 로고
    • Heparins, coumarin, and bone density
    • Monreal M., Olive A., Lafoz E., and Del Rio L. Heparins, coumarin, and bone density. Lancet 338 8768 (1991) 706
    • (1991) Lancet , vol.338 , Issue.8768 , pp. 706
    • Monreal, M.1    Olive, A.2    Lafoz, E.3    Del Rio, L.4
  • 6
    • 0027467168 scopus 로고
    • Osteoporotic fractures and the recurrence of thromboembolism during pregnancy and the puerperium in 184 women undergoing thromboprophylaxis with heparin
    • Dahlman T.C. Osteoporotic fractures and the recurrence of thromboembolism during pregnancy and the puerperium in 184 women undergoing thromboprophylaxis with heparin. Am J Obstet Gynecol 168 4 (1993) 1265-1270
    • (1993) Am J Obstet Gynecol , vol.168 , Issue.4 , pp. 1265-1270
    • Dahlman, T.C.1
  • 8
    • 0028276935 scopus 로고
    • Bone mineral density during long-term prophylaxis with heparin in pregnancy
    • Dahlman T.C., Sjoberg H.E., and Ringertz H. Bone mineral density during long-term prophylaxis with heparin in pregnancy. Am J Obstet Gynecol 170 (1994) 1315-1320
    • (1994) Am J Obstet Gynecol , vol.170 , pp. 1315-1320
    • Dahlman, T.C.1    Sjoberg, H.E.2    Ringertz, H.3
  • 9
    • 0028121058 scopus 로고
    • Comparison of subcutaneous unfractionated heparin with a low molecular weight heparin (Fragmin) in patients with venous thromboembolism and contraindications to coumarin
    • Monreal M., Lafoz E., Olive A., del Rio L., and Vedia C. Comparison of subcutaneous unfractionated heparin with a low molecular weight heparin (Fragmin) in patients with venous thromboembolism and contraindications to coumarin. Thromb Haemost 71 (1994) 7-11
    • (1994) Thromb Haemost , vol.71 , pp. 7-11
    • Monreal, M.1    Lafoz, E.2    Olive, A.3    del Rio, L.4    Vedia, C.5
  • 10
  • 11
    • 0029880831 scopus 로고    scopus 로고
    • The effects of long-term heparin therapy during pregnancy on bone density. A prospective matched cohort study
    • Douketis J.D., Ginsberg J.S., Burrows R.F., Duku E.K., Webber C.E., and Brill-Edwards P. The effects of long-term heparin therapy during pregnancy on bone density. A prospective matched cohort study. Thromb Haemost 75 (1996) 254-257
    • (1996) Thromb Haemost , vol.75 , pp. 254-257
    • Douketis, J.D.1    Ginsberg, J.S.2    Burrows, R.F.3    Duku, E.K.4    Webber, C.E.5    Brill-Edwards, P.6
  • 12
    • 0032724913 scopus 로고    scopus 로고
    • Thromboprophylaxis with low molecular weight heparin (dalteparin) in pregnancy
    • Pettila V., Kaaja R., Leinonen P., Ekblad U., Kataja M., and Ikkala E. Thromboprophylaxis with low molecular weight heparin (dalteparin) in pregnancy. Thromb Res 96 (1999) 275-282
    • (1999) Thromb Res , vol.96 , pp. 275-282
    • Pettila, V.1    Kaaja, R.2    Leinonen, P.3    Ekblad, U.4    Kataja, M.5    Ikkala, E.6
  • 14
    • 0036166519 scopus 로고    scopus 로고
    • Postpartum bone mineral density in women treated for thromboprophylaxis with unfractionated heparin or LMW heparin
    • Pettila V., Leinonen P., Markkola A., Hiilesmaa V., and Kaaja R. Postpartum bone mineral density in women treated for thromboprophylaxis with unfractionated heparin or LMW heparin. Thromb Haemost 87 (2002) 182-196
    • (2002) Thromb Haemost , vol.87 , pp. 182-196
    • Pettila, V.1    Leinonen, P.2    Markkola, A.3    Hiilesmaa, V.4    Kaaja, R.5
  • 15
    • 0028211342 scopus 로고
    • Ex-vivo and in-vitro evidence that low molecular weight heparins exhibit less binding to plasma proteins than unfractionated heparin
    • Young E., Wells P., Holloway S., Weitz J., and Hirsh J. Ex-vivo and in-vitro evidence that low molecular weight heparins exhibit less binding to plasma proteins than unfractionated heparin. Thromb Haemost 71 (1994) 300-304
    • (1994) Thromb Haemost , vol.71 , pp. 300-304
    • Young, E.1    Wells, P.2    Holloway, S.3    Weitz, J.4    Hirsh, J.5
  • 16
    • 0035198865 scopus 로고    scopus 로고
    • Treatment of deep vein thrombosis using low-molecular-weight heparins
    • [discussion S515-23]
    • Groce III J.B. Treatment of deep vein thrombosis using low-molecular-weight heparins. Am J Manag Care 7 17 (2001) S510-S515 [discussion S515-23]
    • (2001) Am J Manag Care , vol.7 , Issue.17
    • Groce III, J.B.1
  • 17
    • 0036878876 scopus 로고    scopus 로고
    • Treatment and prophylaxis of venous thromboembolism during pregnancy
    • Bates S.M. Treatment and prophylaxis of venous thromboembolism during pregnancy. Thromb Res 108 (2002) 97-106
    • (2002) Thromb Res , vol.108 , pp. 97-106
    • Bates, S.M.1
  • 18
    • 0038600299 scopus 로고    scopus 로고
    • Anticoagulation of pregnant women with mechanical heart valves: a systematic review of the literature
    • Chan W.S., Anand S., and Ginsberg J.S. Anticoagulation of pregnant women with mechanical heart valves: a systematic review of the literature. Arch Intern Med 160 (2000) 191-196
    • (2000) Arch Intern Med , vol.160 , pp. 191-196
    • Chan, W.S.1    Anand, S.2    Ginsberg, J.S.3
  • 19
    • 0035129373 scopus 로고    scopus 로고
    • Use of antithrombotic agents during pregnancy
    • Ginsberg J.S., Greer I., and Hirsh J. Use of antithrombotic agents during pregnancy. Chest 119 S1 (2001) S122-S131
    • (2001) Chest , vol.119 , Issue.SUPPL.1
    • Ginsberg, J.S.1    Greer, I.2    Hirsh, J.3
  • 20
    • 0029838671 scopus 로고    scopus 로고
    • Histomorphometric analysis of the effects of standard heparin on trabecular bone in vivo
    • Muir J.M., Andrew M., Hirsh J., Weitz J.I., Young E., Deschamps P., et al. Histomorphometric analysis of the effects of standard heparin on trabecular bone in vivo. Blood 88 4 (1996) 1314-1320
    • (1996) Blood , vol.88 , Issue.4 , pp. 1314-1320
    • Muir, J.M.1    Andrew, M.2    Hirsh, J.3    Weitz, J.I.4    Young, E.5    Deschamps, P.6
  • 21
    • 0033558266 scopus 로고    scopus 로고
    • A histomorphometric evaluation of heparin-induced bone loss after discontinuation of heparin treatment in rats
    • Shaughnessy S.G., Hirsh J., Bhandari M., Muir J.M., Young E., and Weitz J.I. A histomorphometric evaluation of heparin-induced bone loss after discontinuation of heparin treatment in rats. Blood 93 4 (1999) 1231-1236
    • (1999) Blood , vol.93 , Issue.4 , pp. 1231-1236
    • Shaughnessy, S.G.1    Hirsh, J.2    Bhandari, M.3    Muir, J.M.4    Young, E.5    Weitz, J.I.6
  • 22
    • 0030957087 scopus 로고    scopus 로고
    • Low-molecular-weight heparin for obstetric thromboprophylaxis: experience of sixty-nine pregnancies in sixty-one women at high risk
    • Nelson-Piercy C., Letsky E.A., and de Swiet M. Low-molecular-weight heparin for obstetric thromboprophylaxis: experience of sixty-nine pregnancies in sixty-one women at high risk. Am J Obstet Gynecol 176 (1997) 1062-1068
    • (1997) Am J Obstet Gynecol , vol.176 , pp. 1062-1068
    • Nelson-Piercy, C.1    Letsky, E.A.2    de Swiet, M.3
  • 23
    • 0034040773 scopus 로고    scopus 로고
    • Prospective evaluation of bone density in pregnant women receiving the low molecular weight heparin enoxaparin sodium
    • Casele H.L., and Laifer S.A. Prospective evaluation of bone density in pregnant women receiving the low molecular weight heparin enoxaparin sodium. J Matern Fetal Med 9 (2000) 122-125
    • (2000) J Matern Fetal Med , vol.9 , pp. 122-125
    • Casele, H.L.1    Laifer, S.A.2
  • 24
    • 0344493775 scopus 로고    scopus 로고
    • Changes in bone density during long-term administration of low-molecular-weight heparins or acenocoumarol for secondary prophylaxis of venous thromboembolism
    • Wawrzynska L., Tomkowski W.Z., Przedlacki J., Hajduk B., and Torbicki A. Changes in bone density during long-term administration of low-molecular-weight heparins or acenocoumarol for secondary prophylaxis of venous thromboembolism. Pathophysiol Haemost Thromb 33 2 (2003) 64-67
    • (2003) Pathophysiol Haemost Thromb , vol.33 , Issue.2 , pp. 64-67
    • Wawrzynska, L.1    Tomkowski, W.Z.2    Przedlacki, J.3    Hajduk, B.4    Torbicki, A.5
  • 25
    • 2442438933 scopus 로고    scopus 로고
    • Prospective observational study of bone mineral density during pregnancy: low molecular weight heparin versus control
    • Carlin A.J., Farquharson R.G., Quenby S.M., Topping J., and Fraser W.D. Prospective observational study of bone mineral density during pregnancy: low molecular weight heparin versus control. Human Reprod 19 5 (2004) 1211-1214
    • (2004) Human Reprod , vol.19 , Issue.5 , pp. 1211-1214
    • Carlin, A.J.1    Farquharson, R.G.2    Quenby, S.M.3    Topping, J.4    Fraser, W.D.5
  • 26
    • 0030954285 scopus 로고    scopus 로고
    • A histomorphometric comparison of the effects of heparin and low-molecular weight heparin on cancellous bone in rats
    • Muir J.M., Hirsh J., Weitz J.I., Andrew M., Young E., and Shaughnessy S.G. A histomorphometric comparison of the effects of heparin and low-molecular weight heparin on cancellous bone in rats. Blood 89 9 (1997) 3236-3242
    • (1997) Blood , vol.89 , Issue.9 , pp. 3236-3242
    • Muir, J.M.1    Hirsh, J.2    Weitz, J.I.3    Andrew, M.4    Young, E.5    Shaughnessy, S.G.6
  • 27
    • 0029092536 scopus 로고
    • The effects of low molecular weight and standard heparin on calcium loss from fetal rat calvaria
    • Shaughnessy S.G., Young E., Deschamps P., and Hirsh J. The effects of low molecular weight and standard heparin on calcium loss from fetal rat calvaria. Blood 86 4 (1995) 1368-1373
    • (1995) Blood , vol.86 , Issue.4 , pp. 1368-1373
    • Shaughnessy, S.G.1    Young, E.2    Deschamps, P.3    Hirsh, J.4
  • 28
    • 32544453399 scopus 로고    scopus 로고
    • New anticoagulants: anti IIa vs anti Xa- is one better?
    • Bauer K.A. New anticoagulants: anti IIa vs anti Xa- is one better?. J Thromb Thrombolysis 21 1 (2006) 67-72
    • (2006) J Thromb Thrombolysis , vol.21 , Issue.1 , pp. 67-72
    • Bauer, K.A.1
  • 30
    • 6344291877 scopus 로고    scopus 로고
    • Differential effects of heparin and low molecular weight heparin on osteoblastogenesis and adipogenesis in vitro
    • Osip S.L., Butcher M., Young E., Yang L., and Shaughnessy S.G. Differential effects of heparin and low molecular weight heparin on osteoblastogenesis and adipogenesis in vitro. Thromb Haemost 92 (2004) 803-810
    • (2004) Thromb Haemost , vol.92 , pp. 803-810
    • Osip, S.L.1    Butcher, M.2    Young, E.3    Yang, L.4    Shaughnessy, S.G.5
  • 31
    • 0031758031 scopus 로고    scopus 로고
    • The effects of standard and low molecular weight heparin on bone nodule formation in vitro.
    • Bhandari M., Hirsh J., Weitz J.I., Young E., Venner T.J., and Shaughnessy S.G. The effects of standard and low molecular weight heparin on bone nodule formation in vitro. Thromb Haemost 80 (1998) 413-417
    • (1998) Thromb Haemost , vol.80 , pp. 413-417
    • Bhandari, M.1    Hirsh, J.2    Weitz, J.I.3    Young, E.4    Venner, T.J.5    Shaughnessy, S.G.6
  • 32
    • 0025374187 scopus 로고
    • Effects of low molecular weight heparin and unfragmented heparin on induction of osteoporosis in rats
    • Matzsch T., Bergqvist D., Hedner U., Nilsson B., and Ostergaard P. Effects of low molecular weight heparin and unfragmented heparin on induction of osteoporosis in rats. Thromb Haemost 63 (1990) 505-509
    • (1990) Thromb Haemost , vol.63 , pp. 505-509
    • Matzsch, T.1    Bergqvist, D.2    Hedner, U.3    Nilsson, B.4    Ostergaard, P.5
  • 33
    • 0024995517 scopus 로고
    • Heparin-related osteoporosis in rats. A comparative study between unfractionated heparin and low-molecular-weight heparin
    • Monreal M., Vinas L., Monreal L., Lavin S., Lafoz E., and Angles A.M. Heparin-related osteoporosis in rats. A comparative study between unfractionated heparin and low-molecular-weight heparin. Haemostasis 20 (1990) 204-207
    • (1990) Haemostasis , vol.20 , pp. 204-207
    • Monreal, M.1    Vinas, L.2    Monreal, L.3    Lavin, S.4    Lafoz, E.5    Angles, A.M.6
  • 34
    • 0030918053 scopus 로고    scopus 로고
    • Low-molecular-weight heparin (Dalteparin) demonstrated a weaker effect on rat bone metabolism compared with heparin
    • Nishiyama M., Itoh F., and Ujiie A. Low-molecular-weight heparin (Dalteparin) demonstrated a weaker effect on rat bone metabolism compared with heparin. Jpn J Pharmacol 74 (1997) 59-68
    • (1997) Jpn J Pharmacol , vol.74 , pp. 59-68
    • Nishiyama, M.1    Itoh, F.2    Ujiie, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.