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Volumn 81, Issue 7, 2013, Pages 2598-2605

The Dot/Icm Effector SdhA Is Necessary for Virulence of Legionella pneumophila in Galleria mellonella and A/J Mice

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; FLAGELLIN; SDHA PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

EID: 84879433993     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00296-13     Document Type: Article
Times cited : (37)

References (44)
  • 2
    • 0041524018 scopus 로고    scopus 로고
    • Inflammatory response to infectious pulmonary injury
    • Delclaux C, Azoulay E. 2003. Inflammatory response to infectious pulmonary injury. Eur. Respir. J. Suppl. 42:10s-14s
    • (2003) Eur. Respir. J. Suppl. , vol.42
    • Delclaux, C.1    Azoulay, E.2
  • 3
    • 0029155737 scopus 로고
    • Association of Legionella pneumophila with the macrophage endoplasmic reticulum
    • Swanson MS, Isberg RR. 1995. Association of Legionella pneumophila with the macrophage endoplasmic reticulum. Infect. Immun. 63:3609- 3620
    • (1995) Infect. Immun. , vol.63 , pp. 3609-3620
    • Swanson, M.S.1    Isberg, R.R.2
  • 4
    • 0031663585 scopus 로고    scopus 로고
    • Intracellular multiplication and human macrophage killing by Legionella pneumophila are inhibited by conjugal components of IncQ plasmid RSF1010
    • Segal G, Shuman HA. 1998. Intracellular multiplication and human macrophage killing by Legionella pneumophila are inhibited by conjugal components of IncQ plasmid RSF1010. Mol. Microbiol. 30:197-208
    • (1998) Mol. Microbiol. , vol.30 , pp. 197-208
    • Segal, G.1    Shuman, H.A.2
  • 6
    • 81355138899 scopus 로고    scopus 로고
    • Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors
    • Ge J, Shao F. 2011. Manipulation of host vesicular trafficking and innate immune defence by Legionella Dot/Icm effectors. Cell. Microbiol. 13: 1870-1880
    • (2011) Cell. Microbiol. , vol.13 , pp. 1870-1880
    • Ge, J.1    Shao, F.2
  • 7
    • 69549133937 scopus 로고    scopus 로고
    • A Legionella type IV effector activates the NF-_B pathway by phosphorylating the I_B family of inhibitors
    • Ge J, Xu H, Li T, Zhou Y, Zhang Z, Li S, Liu L, Shao F. 2009. A Legionella type IV effector activates the NF-_B pathway by phosphorylating the I_B family of inhibitors. Proc. Natl. Acad. Sci. U. S. A. 106:13725- 13730
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 13725-13730
    • Ge, J.1    Xu, H.2    Li, T.3    Zhou, Y.4    Zhang, Z.5    Li, S.6    Liu, L.7    Shao, F.8
  • 8
    • 83655167093 scopus 로고    scopus 로고
    • Legionella secreted effectors and innate immune responses
    • Luo ZQ. 2012. Legionella secreted effectors and innate immune responses. Cell. Microbiol. 14:19 -27
    • (2012) Cell. Microbiol. , vol.14 , pp. 19-27
    • Luo, Z.Q.1
  • 9
    • 79952203418 scopus 로고    scopus 로고
    • Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila
    • doi:10.1371/journal.ppat .1001289
    • Fontana MF, Banga S, Barry KC, Shen X, Tan Y, Luo ZQ, Vance RE. 2011. Secreted bacterial effectors that inhibit host protein synthesis are critical for induction of the innate immune response to virulent Legionella pneumophila. PLoS Pathog. 7:e1001289. doi:10.1371/journal.ppat .1001289
    • (2011) PLoS Pathog , vol.7
    • Fontana, M.F.1    Banga, S.2    Barry, K.C.3    Shen, X.4    Tan, Y.5    Luo, Z.Q.6    Vance, R.E.7
  • 10
    • 80052153210 scopus 로고    scopus 로고
    • Two signal models in innate immunity
    • Fontana MF, Vance RE. 2011. Two signal models in innate immunity. Immunol. Rev. 243:26 -39
    • (2011) Immunol. Rev. , vol.243 , pp. 26-39
    • Fontana, M.F.1    Vance, R.E.2
  • 13
    • 80053349020 scopus 로고    scopus 로고
    • The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus
    • Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, Shao F. 2011. The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus. Nature 477:596-600
    • (2011) Nature , vol.477 , pp. 596-600
    • Zhao, Y.1    Yang, J.2    Shi, J.3    Gong, Y.N.4    Lu, Q.5    Xu, H.6    Liu, L.7    Shao, F.8
  • 14
    • 0028079788 scopus 로고
    • Replicative Legionella pneumophila lung infection in intratracheally inoculated A/J. mice. A murine model of human Legionnaires' disease.
    • Brieland J, Freeman P, Kunkel R, Chrisp C, Hurley M, Fantone J, Engleberg C. 1994. Replicative Legionella pneumophila lung infection in intratracheally inoculated A/J. mice. A murine model of human Legionnaires' disease. Am. J. Pathol. 145:1537-1546
    • (1994) Am. J. Pathol. , vol.145 , pp. 1537-1546
    • Brieland, J.1    Freeman, P.2    Kunkel, R.3    Chrisp, C.4    Hurley, M.5    Fantone, J.6    Engleberg, C.7
  • 16
    • 73549090166 scopus 로고    scopus 로고
    • Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila
    • doi:10.1371 /journal.ppat.1000665
    • Monroe KM, McWhirter SM, Vance RE. 2009. Identification of host cytosolic sensors and bacterial factors regulating the type I interferon response to Legionella pneumophila. PLoS Pathog. 5:e1000665. doi:10.1371 /journal.ppat.1000665
    • (2009) PLoS Pathog , vol.5
    • Monroe, K.M.1    McWhirter, S.M.2    Vance, R.E.3
  • 17
    • 84859945146 scopus 로고    scopus 로고
    • Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking
    • Ge J, Gong YN, Xu Y, Shao F. 2012. Preventing bacterial DNA release and absent in melanoma 2 inflammasome activation by a Legionella effector functioning in membrane trafficking. Proc. Natl. Acad. Sci. U. S. A. 109:6193- 6198
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 6193-6198
    • Ge, J.1    Gong, Y.N.2    Xu, Y.3    Shao, F.4
  • 19
    • 33845511552 scopus 로고    scopus 로고
    • A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death
    • Laguna RK, Creasey EA, Li Z, Valtz N, Isberg RR. 2006. A Legionella pneumophila-translocated substrate that is required for growth within macrophages and protection from host cell death. Proc. Natl. Acad. Sci. U. S. A. 103:18745-18750
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 18745-18750
    • Laguna, R.K.1    Creasey, E.A.2    Li, Z.3    Valtz, N.4    Isberg, R.R.5
  • 20
    • 84857752089 scopus 로고    scopus 로고
    • The protein SdhA maintains the integrity of the Legionella-containing vacuole
    • Creasey EA, Isberg RR. 2012. The protein SdhA maintains the integrity of the Legionella-containing vacuole. Proc. Natl. Acad. Sci. U. S. A. 109: 3481-3486
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 3481-3486
    • Creasey, E.A.1    Isberg, R.R.2
  • 22
    • 0023006909 scopus 로고
    • Control of Legionella in hospitals
    • Edelstein PH. 1986. Control of Legionella in hospitals. J. Hosp. Infect. 8:109 -115
    • (1986) J. Hosp. Infect. , vol.8
    • Edelstein, P.H.1
  • 23
    • 34249871556 scopus 로고    scopus 로고
    • A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila
    • Sansom FM, Newton HJ, Crikis S, Cianciotto NP, Cowan PJ, d'Apice AJ, Hartland EL. 2007. A bacterial ecto-triphosphate diphosphohydrolase similar to human CD39 is essential for intracellular multiplication of Legionella pneumophila. Cell. Microbiol. 9:1922-1935
    • (2007) Cell. Microbiol. , vol.9 , pp. 1922-1935
    • Sansom, F.M.1    Newton, H.J.2    Crikis, S.3    Cianciotto, N.P.4    Cowan, P.J.5    d'Apice, A.J.6    Hartland, E.L.7
  • 25
    • 33644775553 scopus 로고    scopus 로고
    • Newton HJ, Sansom FM, Bennett-Wood V, Hartland EL. 2006. Identification of Legionella pneumophila-specific genes by genomic subtractive hybridization with Legionella micdadei and identification of lpnE, a gene required for efficient host cell entry. Infect. Immun. 74:1683-1691
    • (2006) , vol.74 , pp. 1683-1691
    • Newton, H.J.1    Sansom, F.M.2    Bennett-Wood, V.3    Hartland, E.L.4
  • 26
    • 0030994460 scopus 로고    scopus 로고
    • Analysis of the Legionella pneumophila fliI gene: intracellular growth of a defined mutant defective for flagellum biosynthesis
    • Merriam JJ, Mathur R, Maxfield-Boumil R, Isberg RR. 1997. Analysis of the Legionella pneumophila fliI gene: intracellular growth of a defined mutant defective for flagellum biosynthesis. Infect. Immun. 65:2497-2501
    • (1997) Infect. Immun. , vol.65 , pp. 2497-2501
    • Merriam, J.J.1    Mathur, R.2    Maxfield-Boumil, R.3    Isberg, R.R.4
  • 29
    • 33645791082 scopus 로고    scopus 로고
    • Flagellindeficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity
    • doi:10.1371/journal.ppat .0020018
    • Ren T, Zamboni DS, Roy CR, Dietrich WF, Vance RE. 2006. Flagellindeficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity. PLoS Pathog. 2:e18. doi:10.1371/journal.ppat .0020018
    • (2006) PLoS Pathog , vol.2
    • Ren, T.1    Zamboni, D.S.2    Roy, C.R.3    Dietrich, W.F.4    Vance, R.E.5
  • 30
    • 84876562347 scopus 로고    scopus 로고
    • The Legionella pneumophila Dot/Icm-secreted effector PlcC/CegC1 together with PlcA and PlcB promotes virulence and belongs to a novel zinc metallophospholipase C family present in bacteria and fungi.
    • Aurass P, Schlegel M, Metwally O, Harding CR, Schroeder GN, Frankel G, Flieger A. 2013. The Legionella pneumophila Dot/Icm-secreted effector PlcC/CegC1 together with PlcA and PlcB promotes virulence and belongs to a novel zinc metallophospholipase C family present in bacteria and fungi. J. Biol. Chem. 288:11080 -11092
    • (2013) J. Biol. Chem. , vol.288 , pp. 11080-11092
    • Aurass, P.1    Schlegel, M.2    Metwally, O.3    Harding, C.R.4    Schroeder, G.N.5    Frankel, G.6    Flieger, A.7
  • 31
    • 83755183815 scopus 로고    scopus 로고
    • Activation of NLRC4 by flagellated bacteria triggers caspase-1-dependent and -independent responses to restrict Legionella pneumophila replication in macrophages and in vivo
    • Pereira MS, Morgantetti GF, Massis LM, Horta CV, Hori JI, Zamboni DS. 2011. Activation of NLRC4 by flagellated bacteria triggers caspase-1-dependent and -independent responses to restrict Legionella pneumophila replication in macrophages and in vivo. J. Immunol. 187:6447- 6455
    • (2011) J. Immunol. , vol.187 , pp. 6447-6455
    • Pereira, M.S.1    Morgantetti, G.F.2    Massis, L.M.3    Horta, C.V.4    Hori, J.I.5    Zamboni, D.S.6
  • 32
    • 84877833716 scopus 로고    scopus 로고
    • Multiple Legionella pneumophila type II secretion substrates, including a novel protein, contribute to differential infection of amoebae Acanthamoeba castellanii, Hartmannella vermiformis, and Naegleria lovaniensis
    • Tyson JY, Pearce MM, Vargas P, Bagchi S, Mulhern BJ, Cianciotto NP. 2013. Multiple Legionella pneumophila type II secretion substrates, including a novel protein, contribute to differential infection of amoebae Acanthamoeba castellanii, Hartmannella vermiformis, and Naegleria lovaniensis. Infect. Immun. 81:1399 -1410
    • (2013) Infect. Immun. , vol.81 , pp. 1399-1410
    • Tyson, J.Y.1    Pearce, M.M.2    Vargas, P.3    Bagchi, S.4    Mulhern, B.J.5    Cianciotto, N.P.6
  • 34
    • 57749209985 scopus 로고    scopus 로고
    • Regulators and signalling in insect haemocyte immunity
    • Marmaras VJ, Lampropoulou M. 2009. Regulators and signalling in insect haemocyte immunity. Cell. Signal. 21:186 -195
    • (2009) Cell. Signal. , vol.21 , pp. 186-195
    • Marmaras, V.J.1    Lampropoulou, M.2
  • 35
    • 84857736359 scopus 로고    scopus 로고
    • Vacuolar pathogens value membrane integrity
    • Roy CR. 2012. Vacuolar pathogens value membrane integrity. Proc. Natl. Acad. Sci. U. S. A. 109:3197-3198
    • (2012) Proc. Natl. Acad. Sci. U. S. A. , vol.109 , pp. 3197-3198
    • Roy, C.R.1
  • 36
    • 67649399024 scopus 로고    scopus 로고
    • Leading a sheltered life: intracellular pathogens and maintenance of vacuolar compartments.
    • Kumar Y, Valdivia RH. 2009. Leading a sheltered life: intracellular pathogens and maintenance of vacuolar compartments. Cell Host Microbe 5:593- 601
    • (2009) Cell Host Microbe , vol.5 , pp. 593-601
    • Kumar, Y.1    Valdivia, R.H.2
  • 37
    • 0345096508 scopus 로고    scopus 로고
    • Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella
    • Bergin D, Brennan M, Kavanagh K. 2003. Fluctuations in haemocyte density and microbial load may be used as indicators of fungal pathogenicity in larvae of Galleria mellonella. Microbes Infect. 5:1389 -1395
    • (2003) Microbes Infect , vol.5 , pp. 1389-1395
    • Bergin, D.1    Brennan, M.2    Kavanagh, K.3
  • 38
    • 0017329642 scopus 로고
    • Studies on the in vivo cellular reactions of insects: an ultrastructural analysis of nodule formation in Galleria mellonella
    • Ratcliffe NA, Gagen SJ. 1977. Studies on the in vivo cellular reactions of insects: an ultrastructural analysis of nodule formation in Galleria mellonella. Tissue Cell 9:73- 85
    • (1977) Tissue Cell , vol.9 , pp. 73-85
    • Ratcliffe, N.A.1    Gagen, S.J.2
  • 39
    • 60649091298 scopus 로고    scopus 로고
    • Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation
    • Buchon N, Broderick NA, Poidevin M, Pradervand S, Lemaitre B. 2009. Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation. Cell Host Microbe 5:200 -211
    • (2009) Cell Host Microbe , vol.5 , pp. 200-211
    • Buchon, N.1    Broderick, N.A.2    Poidevin, M.3    Pradervand, S.4    Lemaitre, B.5
  • 40
    • 77955397296 scopus 로고    scopus 로고
    • Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector of Legionella pneumophila
    • Price CT, Al-Quadan T, Santic M, Jones SC, Abu Kwaik Y. 2010. Exploitation of conserved eukaryotic host cell farnesylation machinery by an F-box effector of Legionella pneumophila. J. Exp. Med. 207:1713-1726
    • (2010) J. Exp. Med. , vol.207 , pp. 1713-1726
    • Price, C.T.1    Al-Quadan, T.2    Santic, M.3    Jones, S.C.4    Abu Kwaik, Y.5
  • 41
    • 78651234971 scopus 로고    scopus 로고
    • Legionella metaeffector exploits host proteasome to temporally regulate cognate effector
    • doi:10.1371/journal.ppat.1001216
    • Kubori T, Shinzawa N, Kanuka H, Nagai H. 2010. Legionella metaeffector exploits host proteasome to temporally regulate cognate effector. PLoS Pathog. 6:e1001216. doi:10.1371/journal.ppat.1001216
    • (2010) PLoS Pathog , vol.6
    • Kubori, T.1    Shinzawa, N.2    Kanuka, H.3    Nagai, H.4
  • 43
    • 78049496542 scopus 로고    scopus 로고
    • Molecular pathogenesis of Listeria monocytogenes in the alternative model host Galleria mellonella
    • Joyce SA, Gahan CG. 2010. Molecular pathogenesis of Listeria monocytogenes in the alternative model host Galleria mellonella. Microbiology 156:3456 -3468
    • (2010) Microbiology , vol.156 , pp. 3456-3468
    • Joyce, S.A.1    Gahan, C.G.2
  • 44
    • 0035085509 scopus 로고    scopus 로고
    • Flagellum of Legionella pneumophila positively affects the early phase of infection of eukaryotic host cells
    • Dietrich C, Heuner K, Brand BC, Hacker J, Steinert M. 2001. Flagellum of Legionella pneumophila positively affects the early phase of infection of eukaryotic host cells. Infect. Immun. 69:2116 -2122.
    • (2001) Infect. Immun. , vol.69 , pp. 2116-2122
    • Dietrich, C.1    Heuner, K.2    Brand, B.C.3    Hacker, J.4    Steinert, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.