The Legionella pneumophila Dot/Icm-secreted effector PlcC/CegC1 together with PlcA and PlcB promotes virulence and belongs to a novel zinc metallophospholipase C family present in bacteria and fungi

Journal of Biological Chemistry

Volumn 288, Issue 16, 2013, Pages 11080-11092

  Aurass, Philipp ^a   Schlegel, Maren ^a   Metwally, Omar ^a   Harding, Clare R ^b   Schroeder, Gunnar N ^b   Frankel, Gad ^b   Flieger, Antje ^a  

^a ROBERT KOCH INSTITUTE   (Germany)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LEGIONELLA; LEGIONELLA PNEUMOPHILA; PHOSPHOLIPASE C;

BACTERIA;

FUNGI;

EDETIC ACID; PHOSPHATIDYLGLYCEROL; PHOSPHATIDYLINOSITOL; PHOSPHOLIPASE; PHOSPHOLIPASE CA; PHOSPHOLIPASE CB; PHOSPHOLIPASE CC; UNCLASSIFIED DRUG; ZINC ION;

AMINO ACID SEQUENCE; ARTICLE; BACTERIAL GROWTH; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ESCHERICHIA COLI; GALLERIA MELLONELLA; HUMAN; HUMAN CELL; LEGIONELLA PNEUMOPHILA; LEGIONNAIRE DISEASE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PSEUDOMONAS FLUORESCENS; SEQUENCE HOMOLOGY;

BACTERIAL PROTEINS; FUNGAL PROTEINS; FUNGI; LEGIONELLA PNEUMOPHILA; METALLOPROTEINS; MUTATION; PHOSPHOLIPASES; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; VIRULENCE FACTORS; ZINC;

FUNGI; LEGIONELLA; LEGIONELLA PNEUMOPHILA; PSEUDOMONAS;

EID: 84876562347     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.426049     Document Type: Article

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