Quantification of pinosylvin in rat plasma by liquid chromatography-tandem mass spectrometry: Application to a pre-clinical pharmacokinetic study

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 931, Issue , 2013, Pages 68-74

  Yeo, Samuel Chao Ming ^a   Luo, Wenxia ^a   Wu, Jinzhu ^b   Ho, Paul C ^a   Lin, Hai Shu ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b HARBIN INSTITUTE OF TECHNOLOGY   (China)

Author keywords

LC ESI MS MS; Oral bioavailability; Pharmacokinetics; Pinosylvin; Resveratrol

Indexed keywords

INTRAVENOUS ADMINISTRATION; LC-ESI-MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LOWER LIMIT OF DETECTIONS; MULTIPLE REACTION MONITORING; ORAL BIOAVAILABILITIES; PINOSYLVIN; SENSITIVE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY;

BIOCHEMISTRY; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; RESVERATROL;

BODY FLUIDS;

PINOSYLVIN; STILBENE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSE ESCALATION; DRUG HALF LIFE; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; MONITORING; MULTIPLE REACTION MONITORING; NONHUMAN; PRECIPITATION; PRIORITY JOURNAL; PROTEIN PROCESSING; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY ANALYSIS; TANDEM MASS SPECTROMETRY; ANIMAL; BIOAVAILABILITY; BLOOD; CHEMISTRY; LIMIT OF DETECTION; MALE; ORAL DRUG ADMINISTRATION; PROCEDURES; REPRODUCIBILITY; SPRAGUE DAWLEY RAT; STATISTICAL MODEL;

RATTUS;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, LIQUID; LIMIT OF DETECTION; LINEAR MODELS; MALE; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; STILBENES; TANDEM MASS SPECTROMETRY;

EID: 84879429022     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.05.023     Document Type: Article

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