Acute renal proximal tubule alterations during induced metabolic crises in a mouse model of glutaric aciduria type 1

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1832, Issue 10, 2013, Pages 1463-1472

  Thies, Bastian ^a   Meyer Schwesinger, Catherine ^a   Lamp, Jessica ^a   Schweizer, Michaela ^a   Koeller, David M ^b   Ullrich, Kurt ^a   Braulke, Thomas ^a   Mühlhausen, Chris ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Acute tubular injury; Dicarboxylate transporter; Glutaric aciduria type 1; Metabolic disease; Transporter expression

Indexed keywords

3 (12 CARBOXY 12 METHYLTRIDECYL) 3 HYDROXYGLUTARIC ACID; COTRANSPORTER; GLUTARIC ACID; GLUTARYL COENZYME A DEHYDROGENASE; ORGANIC ANION TRANSPORTER; SODIUM DEPENDENT DICARBOXYLATE COTRANSPORTER 3; UNCLASSIFIED DRUG;

ACIDURIA; ADRENAL CORTEX INSUFFICIENCY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD; CONTROLLED STUDY; DYSKINESIA; DYSTONIA; GLUTARIC ACIDURIA TYPE 1; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE DAMAGE; KIDNEY TUBULE DISORDER; KIDNEY TUBULE EPITHELIUM; METABOLIC DISORDER; MITOCHONDRION SWELLING; MOLECULAR WEIGHT; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; TISSUES; URINE;

Γ-AMINOBUTYRIC ACID; 3-HYDROXYGLUTARIC ACID; 3OHGA; ACUTE TUBULAR INJURY; DICARBOXYLATE TRANSPORTER; GA; GA1; GABA; GCDH; GLUTARIC ACID; GLUTARIC ACIDURIA TYPE 1; GLUTARYL-COA DEHYDROGENASE; HEPATOCYTE NUCLEAR FACTOR; HIGH PROTEIN DIET; HNF; HPD; MAJOR URINARY PROTEIN 1; METABOLIC DISEASE; MUP1; N-METHYL-D-ASPARTATE; NAC; ND; NHERF; NMDA; NORMAL DIET; OAT; OATP; ORGANIC ANION TRANSPORTER; ORGANIC ANION TRANSPORTING POLYPEPTIDE; PAS; PERIODIC ACID-SCHIFF; RENAL-SPECIFIC TRANSPORTER; RST; SLC; SODIUM HYDROGEN EXCHANGER REGULATORY FACTOR; SODIUM-DEPENDENT DICARBOXYLATE COTRANSPORTER; SOLUTE CARRIER; TRANSPORTER EXPRESSION; WGA; WHEAT GERM AGGLUTININ; WILD-TYPE; WT;

AMINO ACID METABOLISM, INBORN ERRORS; ANIMALS; BRAIN DISEASES, METABOLIC; DISEASE MODELS, ANIMAL; GLUTARATES; GLUTARYL-COA DEHYDROGENASE; KIDNEY TUBULES, PROXIMAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL;

AVENA; MUS;

EID: 84879383463     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2013.04.019     Document Type: Article

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