Regulation of tissue-specific expression of renal organic anion transporters by hepatocyte nuclear factor 1 α/β and DNA methylation

Journal of Pharmacology and Experimental Therapeutics

Volumn 340, Issue 3, 2012, Pages 648-655

  Jin, Li ^a   Kikuchi, Ryota ^a   Saji, Takami ^a   Kusuhara, Hiroyuki ^a   Sugiyama, Yuichi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BISULFITE; CPG DINUCLEOTIDE; DINUCLEOTIDE; HEPATOCYTE NUCLEAR FACTOR 1ALPHA; HEPATOCYTE NUCLEAR FACTOR 1BETA; LUCIFERASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; DOWN REGULATION; ENZYME ASSAY; GEL MOBILITY SHIFT ASSAY; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC ANALYSIS; HUMAN; HUMAN TISSUE; KIDNEY CORTEX; LIVER CELL CULTURE; LIVER PARENCHYMA; MALE; MOLECULAR MECHANICS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANIC ANION TRANSPORTER 1 GENE; ORGANIC ANION TRANSPORTER 3 GENE; ORGANIC ANION TRANSPORTER 4 GENE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN MOTIF; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; TISSUE SPECIFICITY; TRANSACTIVATION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; URATE TRANSPORTER 1 GENE;

ANIMALS; DNA METHYLATION; GENE EXPRESSION REGULATION; HEPATOCYTE NUCLEAR FACTOR 1-ALPHA; HEPATOCYTE NUCLEAR FACTOR 1-BETA; HUMANS; KIDNEY; MALE; MICE; MICE, INBRED C57BL; ORGAN SPECIFICITY; ORGANIC ANION TRANSPORTERS; ORGANIC CATION TRANSPORT PROTEINS; PROMOTER REGIONS, GENETIC;

EID: 84857247515     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.187161     Document Type: Article

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