An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD

Blood

Volumn 121, Issue 17, 2013, Pages 3473-3483

  Zeng, Melody Yue ^a   Pham, Duy ^a   Bagaitkar, Juhi ^b   Liu, Jianyun ^a   Otero, Karel ^b   Shan, Ming ^b   Wynn, Thomas A ^c   Brombacher, Frank ^d,e   Brutkiewicz, Randy R ^a   Kaplan, Mark H ^a   Dinauer, Mary C ^b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d International Center for Genetic Engineering and Biotechnology   (South Africa)

^e UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR ALPHA; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TRANSCRIPTION FACTOR GATA 3; CELL SURFACE RECEPTOR; CYTOKINE; IL4RA PROTEIN, MOUSE;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CHRONIC GRANULOMATOUS DISEASE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFEROCYTOSIS; IMMUNOMODULATION; IN VITRO STUDY; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE ACTIVATION; MOUSE; NATURAL KILLER T CELL; NEUTROPHIL; NONHUMAN; PERITONEAL CAVITY; PERITONEUM EXUDATE; PERITONEUM LAVAGE; PERITONEUM MACROPHAGE; PERITONITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; TISSUE REPAIR; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; IMMUNOLOGY; MACROPHAGE; METABOLISM; PATHOLOGY; PERITONEAL DISEASE; PHAGOCYTOSIS; PHYSIOLOGY; X CHROMOSOME LINKED DISORDER;

ANIMALS; CYTOKINES; GENETIC DISEASES, X-LINKED; GRANULOMATOUS DISEASE, CHRONIC; INFLAMMATION; INTERFERON-GAMMA; INTERLEUKIN-4; MACROPHAGES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NATURAL KILLER T-CELLS; PERITONEAL DISEASES; PHAGOCYTOSIS; RECEPTORS, CELL SURFACE;

MLCS; MLOWN;

EID: 84879381908     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-10-461913     Document Type: Article

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