Prion formation correlates with activation of translation-regulating protein 4E-BP and neuronal transcription factor Elk1

Neurobiology of Disease

Volumn 58, Issue , 2013, Pages 116-122

  Allard, Elin K ^a   Grujic, Mirjana ^a   Fisone, Gilberto ^a   Kristensson, Krister ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Infections; Intracellular signaling; Nervous system; Neurodegenerative diseases; Prions

Indexed keywords

INITIATION FACTOR 4E; INITIATION FACTOR 4G; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; POTASSIUM CHLORIDE; PRION PROTEIN; RAPAMYCIN; TRANSCRIPTION FACTOR ELK 1;

ANIMAL CELL; ARTICLE; BIOACCUMULATION; CELL LEVEL; CONTROLLED STUDY; GENETIC CORRELATION; INTRACELLULAR SIGNALING; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRION; PRION DISEASE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS REGULATION; PROTEIN TARGETING; TRANSCRIPTION REGULATION; TRANSLATION REGULATION; VIRUS STRAIN;

4E-BP; BDNF; BRAIN-DERIVED NEUROTROPHIC FACTOR; BRDU; BROMODEOXIURIDINE; CGP 57380; DIMETHYL SULFOXIDE; DISEASE-ASSOCIATED PRION PROTEIN; DMSO; EIF4E; ERK; EUKARYOTIC INITIATION FACTOR 4E; EUKARYOTIC INITIATION FACTOR 4E BINDING PROTEIN; EXTRACELLULAR SIGNAL-REGULATED KINASE; GT1-1 CELLS; IMMORTALIZED HYPOTHALAMIC GONADOTROPIN-RELEASING HORMONE NEURONS; INFECTIONS; INTRACELLULAR SIGNALING; LEUPEPTIN; LEUPEPTIN HYDROCHLORIDE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAP; MAP KINASE-INTERACTING KINASES; MEK; MEK-INHIBITOR (1,4-DIAMINO-2,3-DICYANO-1,4-BIS(O-AMINOPHENYLMERCAPTO) BUTADIENE ETHANOLATE); MITOGEN-ACTIVATED PROTEIN; MITOGEN-ACTIVATED PROTEIN KINASE KINASE; MNK1-INHIBITOR N3-(4-FLUOROPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE-3,4-DIAMINE; MNK1/2; MTORC1; NERVOUS SYSTEM; NEURODEGENERATIVE DISEASES; NORMAL CELLULAR PRION PROTEIN; P70 RIBOSOMAL S6 KINASE 1; PF-4708671; PRIONS; PRP(C); PRP(SC); RIBOSOMAL PROTEIN S6; S6K1; S6K1-INHIBITOR 2-((4-(5-ETHYLPYRIMIDIN-4-YL)PIPERAZIN-1-YL)METHYL)-5-(TRIFLUOROMETHYL)-1H-BENZO[D]IMIDAZOLE; S6RP; TSC; TUBEROUS SCLEROSIS COMPLEX; U0126;

ANIMALS; BUTADIENES; CARRIER PROTEINS; CELL LINE, TRANSFORMED; ENZYME INHIBITORS; ETS-DOMAIN PROTEIN ELK-1; HISTONES; HYPOTHALAMUS; MICE; MULTIPROTEIN COMPLEXES; NEURONS; NITRILES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; POTASSIUM CHLORIDE; PRIONS; SIGNAL TRANSDUCTION; SIROLIMUS; TOR SERINE-THREONINE KINASES; TRANSFECTION;

EID: 84879367394     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2013.05.014     Document Type: Article

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