Recombination of replicon and helper RNAs and the emergence of propagation-competent vectors upon Sindbis virus vector production

International Journal of Molecular Medicine

Volumn 32, Issue 2, 2013, Pages 410-422

  Hyvärinen, Anna ^a,b   Yongabi, Felicitas ^a   Mäkinen, Kimmo ^c   Wahlfors, Jarmo ^a,c   Pellinen, Riikka ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b NORTH KARELIA CENTRAL HOSPITAL   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Alphavirus vector; Propagation competent virus; Recombination; Sindbis virus; Virus vector

Indexed keywords

ALPHA INTERFERON; HELPER RNA; INTERFERON; RNA; SINDBIS SPLIT HELPER VECTOR; SINDBIS VIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; CYTOPATHOGENIC EFFECT; HUMAN; HUMAN CELL; MIXED INFECTION; NONHUMAN; PRIORITY JOURNAL; RAT; REPLICON; VIRUS GENOME; WILD TYPE;

ANIMALS; CELL LINE; CRICETINAE; GENE EXPRESSION; GENETIC VECTORS; HELPER VIRUSES; INTERFERON TYPE I; RECOMBINATION, GENETIC; REPLICON; SINDBIS VIRUS; TRANSDUCTION, GENETIC; TRANSGENES; VIRAL PLAQUE ASSAY; VIRUS REPLICATION;

EID: 84879345920     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2013.1395     Document Type: Article

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