Progress in the development of animal models of acute kidney injury and its impact on drug discovery

Expert Opinion on Drug Discovery

Volumn 8, Issue 7, 2013, Pages 879-895

  Sanz, Ana B ^a,b   Sanchez Niño, María Dolores ^c   Martín Cleary, Catalina ^a,b   Ortiz, Alberto ^a,b,d   Ramos, Adrián M ^a,b  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b Instituto Carlos IIIFEDER   (Spain)

^c HOSPITAL UNIVERSITARIO LA PAZ IDIPAZ   (Spain)

^d Section of Nephrology   (Spain)

Author keywords

Apoptosis; Fibrosis; Inflammation; Kidney; Necroptosis; Nephrotoxicity; Transgenic mice; TWEAK

Indexed keywords

AC 607; ACETYLCYSTEINE; ARISTOLOCHIC ACID; ATRIAL NATRIURETIC FACTOR ALPHA; CELL THERAPY AGENT; ECULIZUMAB; ERYTHROPOIETIN; FENOLDOPAM; I 5NP; NESIRITIDE; PLACEBO; UNCLASSIFIED DRUG; WARFARIN;

ACUTE KIDNEY FAILURE; CHRONIC KIDNEY DISEASE; DISEASE COURSE; DROSOPHILA; EXPERIMENTAL MODEL; GENE; GENE EXPRESSION SYSTEM; HEMATURIA; HEMOLYTIC UREMIC SYNDROME; HUMAN; KIDNEY ARTERY STENOSIS; KIDNEY FIBROSIS; KIDNEY ISCHEMIA; KIDNEY PROXIMAL TUBULE; MESENCHYMAL STEM CELL; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RAT; REPERFUSION INJURY; REVIEW; RNA INTERFERENCE; THROMBOTIC THROMBOCYTOPENIC PURPURA; ZEBRA FISH;

ACUTE KIDNEY INJURY; ANIMALS; DISEASE MODELS, ANIMAL; DROSOPHILA; DRUG DISCOVERY; HUMANS; KIDNEY; MICE; MICE, TRANSGENIC; ZEBRAFISH;

EID: 84879334306     PISSN: 17460441     EISSN: 1746045X     Source Type: Journal    
DOI: 10.1517/17460441.2013.793667     Document Type: Review

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