Optimization of α-tocopherol loaded solid lipid nanoparticles by central composite design

Industrial Crops and Products

Volumn 49, Issue , 2013, Pages 278-285

  De Carvalho, Sabrina Matos ^a   Noronha, Carolina Montanheiro ^a   Floriani, Caroline Louise ^a   Lino, Renata Calegari ^a   Rocha, Gabriela ^a   Bellettini, Ismael Casagrande ^a   Ogliari, Paulo José ^a   Barreto, Pedro Luiz Manique ^a  

^a FEDERAL UNIVERSITY OF SANTA CATARINA   (Brazil)

Author keywords

Antioxidant; High pressure homogenization; Solid lipid nanoparticle; Surface response design

Indexed keywords

CENTRAL COMPOSITE DESIGNS; HIGH PRESSURE HOMOGENIZATION; MEAN PARTICLE SIZE; OPTIMAL CONDITIONS; PHYSICAL STABILITY; RESPONSE SURFACE METHODOLOGY; SOLID LIPID NANOPARTICLE (SLN); SURFACE RESPONSE DESIGNS;

ANTIOXIDANTS; DIFFERENTIAL SCANNING CALORIMETRY; NANOPARTICLES; PARTICLE SIZE; X RAY DIFFRACTION ANALYSIS; ZETA POTENTIAL;

OPTIMIZATION;

ANTIOXIDANT; HOMOGENEITY; LIPID; NANOTECHNOLOGY; OPTIMIZATION; VITAMIN;

EID: 84879319098     PISSN: 09266690     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.indcrop.2013.04.054     Document Type: Article

References (48)

1. Araújo J., Gonzalez-Mira E., Egea M.A., García M.L., Souto E.B. Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. Int. J. Pharm. 2010, 393:168-176.
2. Baş D., Boyaci{dotless} I.H. Modeling and optimization I: usability of response surface methodology. J. Food Eng. 2007, 78:836-845.
3. Brewer M.S. Natural antioxidants: sources, compounds, mechanisms of action, and potential applications. Compr. Rev. Food Sci. Food Saf. 2011, 10:221-247.
4. Brubach J.B., Jannin V., Mahler B., Bourgaux C., Lessieur P., Roy P., Ollivon M. Structural and thermal characterization of glyceryl behenate by X-ray diffraction coupled to differential calorimetry and infrared spectroscopy. Int. J. Pharm. 2007, 336:248-256.
5. Bunjes H., Unruh T. Characterization of lipid nanoparticles by differential scanning calorimetry, X-ray and neutron scattering. Adv. Drug Deliv. Rev. 2007, 59:379-402.
6. Byun Y., Hwang J.B., Bang S.H., Darby D., Cooksey K., Dawson P.L., Park H.J., Whiteside S.V. Formulation and characterization of α-tocopherol loaded poly ε-caprolactone (PCL) nanoparticles. Food Sci. Technol. 2011, 44:24-28.
7. Calado V., Montgomery D.C. Planejamento de Experimentos usando Statistica 2003, E-Papers Serviços Editoriais, Rio de Janeiro.
8. Chapman D. The polymorphism of glycerides. Chem. Rev. 1962, 62:433-456.
9. Chen H.-L., Hwang J.C. Some comments on the degree of crystallinity defined by the enthalpy of melting. Polymer 1995, 36:4355-4357.
10. Cheong J.N., Tan C.P., Man Y.B.C., Misran M. α-Tocopherol nanodispersions: preparation, characterization and stability evaluation. J. Food Eng. 2008, 89:204-209.
11. Dingler A., Blum R.P., Niehus H., Müller R.H., Gohla S. Solid lipid nanoparticles (SLN™/lipopearls™): a pharmaceutical and cosmetic carrier for the application of vitamin E in dermal products. J. Microencapsul. 1999, 16:751-767.
12. Evans J.C., Kodali D.R., Addis P.B. Optimal tocopherol concentrations to inhibit soybean oil oxidation. J. Am. Oil Chem. Soc. 2002, 79:47-51.
13. Fang J.-Y., Fang C.-L., Liu C.-H., Su Y.-H. Lipid nanoparticles as vehicles for topical psoralen delivery: solid lipid nanoparticles (SLN) versus nanostructured lipid carriers (NLC). Eur. J. Pharm. Biopharm. 2008, 70:633-640.
14. Freitas C., Müller R.H. Correlation between long-term stability of solid lipid nanoparticles (SLN™) and crystallinity of the lipid phase. Eur. J. Pharm. Biopharm. 1999, 47:125-132.
15. Freitas C., Müller R.H. Effect of light and temperature on zeta potential and physical stability in solid lipid nanoparticle (SLN™) dispersions. Int. J. Pharm. 1998, 168:221-229.
16. Gonnet M., Lethuaut L., Boury F. New trend in encapsulation of liposoluble vitamins. J. Control. Release 2010, 146:276-290.
17. Gonzalez-Mira E., Egea M.A., Souto E.B., Calpena A.C., García M.L. Optimizing flurbiprofen-loaded NLC by central composite factorial design for ocular delivery. Nanotechnology 2011, 22:1-15.
18. Han F., Li S., Yin R., Liu H., Xu L. Effect of surfactants on the formation and characterization of a new type of colloidal drug delivery system: nanostructured lipid carriers. Colloids Surf. A 2008, 315:210-216.
19. Hao J., Fang X., Zhou Y., Wang J., Guo F., Li F., Peng X. Development and optimization of solid lipid nanoparticle formulation for ophthalmic delivery of chloramphenicol using a Box-Behnken design. Int. J. Nanomed. 2011, 6:683-692.
20. Hatanaka J., Chikamoria H., Sato H., Uchida S., Debari K., Onoue S., Yamada S. Physicochemical and pharmacological characterization of α-tocopherol-loaded nano-emulsion system. Int. J. Pharm. 2010, 396:188-193.
21. Helgason T., Awad T.S., Kristbergsson K., Decker E.A., Mcclements D.J., Weiss J. Impact of surfactant properties on oxidative stability of β-carotene encapsulated within solid lipid nanoparticles. J. Agric. Food Chem. 2009, 57:8033-8040.
22. Helgason T., Awad T.S., Kristbergsson K., McClements D.J., Weiss J. Effect of surfactant surface coverage on formation of solid lipid nanoparticles (SLN). J. Colloid Interface Sci. 2009, 334:75-81.
23. Jores K., Mehnert W., Mäder K. Physicochemical investigations on solid lipid nanoparticles and on oil-loaded solid lipid nanoparticles: a nuclear magnetic resonance and electron spin resonance study. Pharm. Res. 2003, 20:1274-1283.
24. Karn-orachai K., Ruktanonchai U., Smith S.M. Effect of surfactant on characteristics of solid lipid nanoparticles (SLN). Adv. Mater. Res. 2012, 364:313-316.
25. Long C., Zhang L., Qian Y. Preparation and crystal modification of ibuprofen-loaded solid lipid microparticles. Chin. J. Chem. Eng. 2006, 14:518-525.
26. Lutton E.S. Review of the polymorphism of saturated even glycerides. J. Am. Oil Chem. Soc. 1950, 27:276-281.
27. Marcato P.D. Preparação, caracterização e aplicaçes em fármacos e cosméticos de nanopartículas lipídicas sólidas. Rev. Eletr. Farm. 2009, 6:1-37.
28. McGauley S.E., Marangoni A.G. Static crystallization behavior of cocoa butter and its relationship to network microstructure. Physical Properties of Lipids 2002, 85-124. Marcel Dekker, Inc., New York. A.G. Marangoni, S.S. Narine (Eds.).
29. Mehnert W., Mäder K. Solid lipid nanoparticles: production, characterization and applications. Adv. Drug Deliv. Rev. 2012, 64:83-101.
30. Mehnert W., Mäder K. Solid lipid nanoparticles: production, characterization and applications. Adv. Drug Deliv. Rev. 2001, 47:165-196.
31. Mozafari M.R., Flanagan J., Matia-Merino L., Awati A., Omri A., Suntres Z.E., Singh H.J. Recent trends in the lipid-based nanoencapsulation of antioxidants and their role in foods. J. Sci. Food Agric. 2006, 86:2038-2045.
32. Müller R.H., Mäder K., Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art. Eur. J. Pharm. Biopharm. 2000, 50:161-177.
33. Müller R.H., Radtke M., Wissing S.A. Nanostructured lipid matrices for improved microencapsulation of drugs. Int. J. Pharm. 2002, 242:121-128.
34. Ndhlala A.R., Moyo M., Van Staden J. Natural antioxidants: fascinating or mythical biomolecules?. Molecules 2010, 15:6905-6930.
35. Sato K. Crystallization of fats and fatty acids. Crystallization and Polymorphism of Fats and Fatty Acids (Surfactant Science Series) 1988, 267-303. Marcel Dekker Inc., New York. N. Garti, K. Sato (Eds.).
36. Saupe A., Rades T. Solid lipid nanoparticle. Nanocarrier Technologies: Frontiers of Nanotherapy 2006, 41-50. Springer, Dordrecht. M.R. Mozafari (Ed.).
37. Schaffazick S.R., Guterres S.S., Freitas L.L., de Pohlmann A.R. Caracterização e estabilidade físico-química de sistemas poliméricos nanoparticulados para administração de fármacos. Quim. Nova 2003, 26:726-737.
38. Shahidi F., Zhong Y. Novel antioxidants in food quality preservation and health promotion. Eur. J. Lipid Sci. Technol. 2010, 112:930-940.
39. Sinha V.R., Srivastava S., Goel H., Jindal V. Solid lipid nanoparticles (SLN'S): trends and implications in drug targeting. Int. J. Adv. Pharm. Sci. 2010, 1:212-238.
40. ®888 ATO as bulk lipid and as SLN and NLC. J. Microencapsul. 2006, 23:417-433.
41. Tan C.P., Nakajima M. β-Carotene nanodispersions: preparation, characterization and stability evaluation. Food Chem. 2005, 92:661-671.
42. Teeranachaideekul V., Müller R.H., Junyaprasert V.B. Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC): effects of formulation parameters on physicochemical stability. Int. J. Pharm. 2007, 340:198-206.
43. van Aardt M., Duncan S.E., Long T.E., O'Keefe S.F., Marcy J.E., Sims S.R. Effect of antioxidants on oxidative stability of edible fats and oils: thermogravimetric analysis. J. Agric. Food Chem. 2004, 52:587-591.
44. Weiss J., Decker E.A., McClements D.J., Kristbergsson K., Helgason T., Awad T. Solid lipid nanoparticles as delivery systems for bioactive food components. Food Biophys. 2008, 3:146-154.
45. Wu L., Zhang J., Watanabe W. Physical and chemical stability of drug nanoparticles. Adv. Drug Deliv. Rev. 2011, 63:456-469.
46. Yenílmez E., Yazan Y. Release of vitemin E from different topical colloidal delivery systems and their in vitro-in vivo evaluation. Turk. J. Pharm. Sci. 2010, 7:167-188.
47. Yoo S.-H., Song Y-B., Chang P.-S., Lee H.G. Microencapsulation of α-tocopherol using sodium alginate and its controlled release properties. Int. J. Biol. Macromol. 2006, 38:25-30.
48. zur Mühlen A., Schwarz C., Mehnert W. Solid lipid nanoparticles (SLN) for controlled drug delivery: drug release and release mechanism. Eur. J. Pharm. Biopharm. 1998, 45:149-155.