Unphosphorylated STAT5A stabilizes heterochromatin and suppresses tumor growth

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 25, 2013, Pages 10213-10218

  Hu, Xiaoyu ^a   Dutta, Pranabananda ^a,b   Tsurumi, Amy ^a   Li, Jinghong ^b   Wang, Jingtong ^b   Land, Hartmut ^a   Li, Willis X ^a,b  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Drosophila; Fluorescence recovery after photobleaching (FRAP); JAK STAT; Transcription

Indexed keywords

HETEROCHROMATIN PROTEIN 1; HETEROCHROMATIN PROTEIN 1ALPHA; STAT5A PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING KINETICS; CANCER GROWTH; CARCINOGENESIS; CELL PROLIFERATION; COLON CANCER; COMPETITIVE INHIBITION; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; FEMALE; FLOW CYTOMETRY; GENE DELETION; HELA CELL; HETEROCHROMATIN; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STABILITY; SOMATIC MUTATION; TUMOR XENOGRAFT;

DROSOPHILA; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING (FRAP); JAK/STAT; TRANSCRIPTION;

ANIMALS; CELL NUCLEUS; CELL PROLIFERATION; CHROMOSOMAL PROTEINS, NON-HISTONE; COLONIC NEOPLASMS; DATABASES, GENETIC; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HELA CELLS; HETEROCHROMATIN; HUMANS; MICE; PHOSPHORYLATION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT5 TRANSCRIPTION FACTOR; TRANSCRIPTOME; TUMOR SUPPRESSOR PROTEINS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84879292795     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1221243110     Document Type: Article

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