Nicotinamide: A class III HDACi delays in vitro aging of mouse oocytes

Journal of Reproduction and Development

Volumn 59, Issue 3, 2013, Pages 238-244

  Lee, Ah Reum ^a   Kishigami, Satoshi ^a,c   Amano, Tomoko ^a   Matsumoto, Kazuya ^a   Wakayama, Teruhiko ^b,d   Hosoi, Yoshihiko ^a  

^a KINKI UNIVERSITY   (Japan)

^b RIKEN Center for Biosystems Dynamics Research   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d UNIVERSITY OF YAMANASHI   (Japan)

Author keywords

Astral microtubules; Cellular fragmentation; Chromosome scattering; Histone deacetylase; Nicotinamide; Oocyte aging; Spindle elongation; Trichostatin A; Tubulin acetylation

Indexed keywords

MAMMALIA;

EID: 84879286554     PISSN: 09168818     EISSN: 13484400     Source Type: Journal    
DOI: 10.1262/jrd.2012-171     Document Type: Article

References (46)

1. Yanagimachi R, Chang MC. Fertilizable life of golden hamster ova and their morphological changes at the time of losing fertilizability. J Exp Zool 1961; 148: 185-203. [Medline] [CrossRef]
2. Miao YL, Kikuchi K, Sun QY, Schatten H. Oocyte aging: cellular and molecular changes, developmental potential and reversal possibility. Hum Reprod Update 2009; 15: 573-585. [Medline] [CrossRef]
3. Goud P, Goud A, Van Oostveldt P, Van der Elst J, Dhont M. Fertilization abnormalities and pronucleus size asynchrony after intracytoplasmic sperm injection are related to oocyte postmaturity. Fertil Steril 1999; 72: 245-252. [Medline] [CrossRef]
4. Lanman JT. Delays during reproduction and their effects on the embryo and fetus. 2. Aging of eggs. New Engl J Med 1968; 278: 1047-1054. [Medline] [CrossRef]
5. Sakai N, Endo A. Effects of delayed mating on preimplantation embryos in spontaneously ovulated mice. Gamete Res 1988; 19: 381-385. [Medline] [CrossRef]
6. Takase K, Ishikawa M, Hoshiai H. Apoptosis in the degeneration process of unfertilized mouse ova. Tohoku J Exp Med 1995; 175: 69-76. [Medline] [CrossRef]
7. Morita Y, Tilly JL. Oocyte apoptosis: like sand through an hourglass. Dev Biol 1999; 213: 1-17. [Medline] [CrossRef]
8. Perez GI, Tao XJ, Tilly JL. Fragmentation and death (a.k.a. apoptosis) of ovulated oocytes. Mol Hum Reprod 1999; 5: 414-420. [Medline] [CrossRef]
9. Gordo AC, Rodrigues P, Kurokawa M, Jellerette T, Exley GE, Warner C, Fissore R. Intracellular calcium oscillations signal apoptosis rather than activation in in vitro aged mouse eggs. Biol Reprod 2002; 66: 1828-1837. [Medline] [CrossRef]
10. Brison DR, Schultz RM. Increased incidence of apoptosis in transforming growth factor alpha-deficient mouse blastocysts. Biol Reprod 1998; 59: 136-144. [Medline] [CrossRef]
11. Brewster JL, Martin SL, Toms J, Goss D, Wang K, Zachrone K, Davis A, Carlson G, Hood L, Coffin JD. Deletion of Dad1 in mice induces an apoptosis-associated embryonic death. Genesis 2000; 26: 271-278. [Medline] [CrossRef]
12. Liu L, Keefe DL. Cytoplasm mediates both development and oxidation-induced apoptotic cell death in mouse zygotes. Biol Reprod 2000; 62: 1828-1834. [Medline] [CrossRef]
13. Liu L, Trimarchi JR, Keefe DL. Involvement of mitochondria in oxidative stress-induced cell death in mouse zygotes. Biol Reprod 2000; 62: 1745-1753. [Medline] [CrossRef]
14. Moley KH. Diabetes and preimplantation events of embryogenesis. Semin Reprod Endocrinol 1999; 17: 137-151. [Medline] [CrossRef]
15. Tarín JJ, Ten J, Vendrell FJ, Cano A. Dithiothreitol prevents age-associated decrease in oocyte/conceptus viability in vitro. Hum Reprod 1998; 13: 381-386. [Medline] [Cross-Ref]
16. Rausell F, Pertusa JF, Gómez-Piquer V, Hermenegildo C, García-Pérez MA, Cano A, Tarín JJ. Beneficial effects of dithiothreitol on relative levels of glutathione S-transferase activity and thiols in oocytes, and cell number, DNA fragmentation and allocation at the blastocyst stage in the mouse. Mol Reprod Dev 2007; 74: 860-869. [Medline] [CrossRef]
17. Goud AP, Goud PT, Diamond MP, Abu-Soud HM. Nitric oxide delays oocyte aging. Biochemistry 2005; 44: 11361-11368. [Medline] [CrossRef]
18. Ono T, Mizutani E, Li C, Yamagata K, Wakayama T. Offspring from intracytoplasmic sperm injection of aged mouse oocytes treated with caffeine or MG132. Genesis 2011; 49: 460-471. [Medline] [CrossRef]
19. Blackwell L, Norris J, Suto CM, Janzen WP. The use of diversity profiling to characterize chemical modulators of the histone deacetylases. Life Sci 2008; 82: 1050-1058. [Medline] [CrossRef]
20. Imai S, Armstrong CM, Kaeberlein M, Guarente L. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000; 403: 795-800. [Medline] [CrossRef]
21. Taylor DM, Maxwell MM, Luthi-Carter R, Kazantsev AG. Biological and potential therapeutic roles of sirtuin deacetylases. Cell Mol Life Sci 2008; 65: 4000-4018. [Medline] [CrossRef]
22. Xu P, Sauve AA. Vitamin B3, the nicotinamide adenine dinucleotides and aging. Mech Ageing Dev 2010; 131: 287-298. [Medline] [CrossRef]
23. Bitterman KJ, Anderson RM, Cohen HY, Latorre-Esteves M, Sinclair DA. Inhibition of silencing and accelerated aging by nicotinamide, a putative negative regulator of yeast sir2 and human SIRT1. J Biol Chem 2002; 277: 45099-45107. [Medline]
24. Anderson RM, Bitterman KJ, Wood JG, Medvedik O, Sinclair DA. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 2003; 423: 181-185. [Medline] [CrossRef]
25. Gallo CM, Smith DL Jr, Smith JS. Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity. Mol Cell Biol 2004; 24: 1301-1312. [Medline] [CrossRef]
26. Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 2001; 107: 137-148. [Medline] [CrossRef]
27. Huang JC, Yan LY, Lei ZL, Miao YL, Shi LH, Yang JW, Wang Q, Ouyang YC, Sun QY, Chen DY. Change in histone acetylation during postovulatory aging of mouse oocyte. Biol Reprod 2007; 77: 666-670. [Medline] [CrossRef]
28. Ješeta M, Petr J, Krejcová T, Chmelíková E, Jílek F. In vitro ageing of pig oocytes: effects of the histone deacetylase inhibitor trichostatin A. Zygote 2008; 16: 145-152. [Medline] [CrossRef]
29. Wakayama S, Thuan NV, Kishigami S, Ohta H, Mizutani E, Hikichi T, Miyake M, Wakayama T. Production of offspring from one-day-old oocytes stored at room temperature. J Reprod Dev 2004; 50: 627-637. [Medline] [CrossRef]
30. Perez GI, Knudson CM, Leykin L, Korsmeyer SJ, Tilly JL. Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction. Nature Med 1997; 3: 1228-1232. [Medline] [CrossRef]
31. Morita Y, Perez GI, Maravei DV, Tilly KI, Tilly JL. Targeted expression of Bcl-2 in mouse oocytes inhibits ovarian follicle atresia and prevents spontaneous and chemotherapy-induced oocyte apoptosis in vitro. Mol Endocrinol 1999; 13: 841-850. [Medline] [CrossRef]
32. Avalos JL, Bever KM, Wolberger C. Mechanism of sirtuin inhibition by nicotinamide: altering the NAD(+) cosubstrate specificity of a Sir2 enzyme. Mol Cell 2005; 17: 855-868. [Medline] [CrossRef]
33. Cheng HL, Mostoslavsky R, Saito S, Manis JP, Gu Y, Patel P, Bronson R, Appella E, Alt FW, Chua KF. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci USA 2003; 100: 10794-10799. [Medline] [CrossRef]
34. North BJ, Marshall BL, Borra MT, Denu JM, Verdin E. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol Cell 2003; 11: 437-444. [Medline] [CrossRef]
35. Wang H, Cheng H, Wang K, Wen T. Different effects of histone deacetylase inhibitors nicotinamide and trichostatin A (TSA) in C17.2 neural stem cells. J Neural Transm 2012 [Epub ahead of print].
36. Kawamura Y, Uchijima Y, Horike N, Tonami K, Nishiyama K, Amano T, Asano T, Kurihara Y, Kurihara H. Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest. J Clin Invest 2010; 120: 2817-2828. [Medline] [CrossRef]
37. Schatten G, Simerly C, Asai DJ, Szöke E, Cooke P, Schatten H. Acetylated alphatubulin in microtubules during mouse fertilization and early development. Dev Biol 1988; 130: 74-86. [Medline] [CrossRef]
38. Piperno G, LeDizet M, Chang XJ. Microtubules containing acetylated alpha-tubulin in mammalian cells in culture. J Cell Biol 1987; 104: 289-302. [Medline] [CrossRef]
39. Eichenlaub-Ritter U, Chandley AC, Gosden RG. Alterations to the microtubular cytoskeleton and increased disorder of chromosome alignment in spontaneously ovulated mouse oocytes aged in vivo: an immunofluorescence study. Chromosoma 1986; 94: 337-345. [Medline] [CrossRef]
40. Hubbert C, Guardiola A, Shao R, Kawaguchi Y, Ito A, Nixon A, Yoshida M, Wang XF, Yao TP. HDAC6 is a microtubule-associated deacetylase. Nature 2002; 417: 455-458. [Medline] [CrossRef]
41. Schemies J, Sippl W, Jung M. Histone deacetylase inhibitors that target tubulin. Cancer Lett 2009; 280: 222-232. [Medline] [CrossRef]
42. Akella JS, Wloga D, Kim J, Starostina NG, Lyons-Abbott S, Morrissette NS, Dougan ST, Kipreos ET, Gaertig J. MEC-17 is an alpha-tubulin acetyltransferase. Nature 2010; 467: 218-222. [Medline] [CrossRef]
43. Miki H, Inoue K, Ogonuki N, Mochida K, Nagashima H, Baba T, Ogura A. Cytoplasmic asters are required for progression past the first cell cycle in cloned mouse embryos. Biol Reprod 2004; 71: 2022-2028. [Medline] [CrossRef]
44. Navara CS, Wu GJ, Simerly C, Schatten G. Mammalian model systems for exploring cytoskeletal dynamics during fertilization. Curr Top Dev Biol 1995; 31: 321-342. [Medline] [CrossRef]
45. Schatten H, Schatten G, Mazia D, Balczon R, Simerly C. Behavior of centrosomes during fertilization and cell division in mouse oocytes and in sea urchin eggs. Proc Natl Acad Sci USA 1986; 83: 105-109. [Medline] [CrossRef]
46. Antonio C, Ferby I, Wilhelm H, Jones M, Karsenti E, Nebreda AR, Vernos I. Xkid, a chromokinesin required for chromosome alignment on the metaphase plate. Cell 2000; 102: 425-435. [Medline] [CrossRef]