메뉴 건너뛰기




Volumn 33, Issue 5, 2013, Pages 954-964

Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulation

Author keywords

autoantibody; dsDNA; extractable nuclear antigen; glomerulonephritis; systemic lupus erythematosus; Toll like receptor

Indexed keywords

ALPHA INTERFERON; AUTOANTIBODY; DOUBLE STRANDED DNA ANTIBODY; EXTRACTABLE NUCLEAR ANTIGEN ANTIBODY; INTERFERON REGULATORY FACTOR 7; MESSENGER RNA; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

EID: 84879226183     PISSN: 02719142     EISSN: 15732592     Source Type: Journal    
DOI: 10.1007/s10875-013-9887-0     Document Type: Article
Times cited : (63)

References (39)
  • 1
    • 14244250736 scopus 로고    scopus 로고
    • Autoantibody explosion in systemic lupus erythematosus: More than 100 different antibodies found in SLE patients
    • 15505768 10.1016/j.semarthrit.2004.07.002 1:CAS:528:DC%2BD2cXovVyqsLw%3D
    • Sherer Y, Gorstein A, Fritzler MJ, Shoenfeld Y. Autoantibody explosion in systemic lupus erythematosus: more than 100 different antibodies found in SLE patients. Semin Arthritis Rheum. 2004;34(2):501-37.
    • (2004) Semin Arthritis Rheum , vol.34 , Issue.2 , pp. 501-537
    • Sherer, Y.1    Gorstein, A.2    Fritzler, M.J.3    Shoenfeld, Y.4
  • 2
    • 34248146162 scopus 로고    scopus 로고
    • Systemic lupus erythematosus
    • 16722594 10.1186/1750-1172-1-6
    • Manson JJ, Rahman A. Systemic lupus erythematosus. Orphanet J Rare Dis. 2006;1:6.
    • (2006) Orphanet J Rare Dis , vol.1 , pp. 6
    • Manson, J.J.1    Rahman, A.2
  • 3
    • 20244383590 scopus 로고    scopus 로고
    • Relationship between anti-double-stranded DNA antibodies and exacerbation of renal disease in patients with systemic lupus erythematosus
    • 15818711 10.1002/art.20980 1:CAS:528:DC%2BD2MXktFCkt7Y%3D
    • Linnik MD, Hu JZ, Heilbrunn KR, Strand V, Hurley FL, Joh T. Relationship between anti-double-stranded DNA antibodies and exacerbation of renal disease in patients with systemic lupus erythematosus. Arthritis Rheum. 2005;52(4):1129-37.
    • (2005) Arthritis Rheum , vol.52 , Issue.4 , pp. 1129-1137
    • Linnik, M.D.1    Hu, J.Z.2    Heilbrunn, K.R.3    Strand, V.4    Hurley, F.L.5    Joh, T.6
  • 4
    • 33645818775 scopus 로고    scopus 로고
    • Prevalence and clinico-serological correlations of anti-alpha-enolase, anti-C1q, and anti-dsDNA antibodies in patients with systemic lupus erythematosus
    • 16583471 1:CAS:528:DC%2BD28XksFCks7g%3D
    • Mosca M, Chimenti D, Pratesi F, Baldini C, Anzilotti C, Bombardieri S, et al. Prevalence and clinico-serological correlations of anti-alpha-enolase, anti-C1q, and anti-dsDNA antibodies in patients with systemic lupus erythematosus. J Rheumatol. 2006;33(4):695-7.
    • (2006) J Rheumatol , vol.33 , Issue.4 , pp. 695-697
    • Mosca, M.1    Chimenti, D.2    Pratesi, F.3    Baldini, C.4    Anzilotti, C.5    Bombardieri, S.6
  • 5
    • 0029953732 scopus 로고    scopus 로고
    • Utility of anti-Sm, anti-RNP, anti-Ro/SS-A, and anti-La/SS-B (extractable nuclear antigens) detected by enzyme-linked immunosorbent assay for the diagnosis of systemic lupus erythematosus
    • 8651971 10.1002/art.1780390626 1:STN:280:DyaK283jt1Cguw%3D%3D
    • Sanchez-Guerrero J, Lew RA, Fossel AH, Schur PH. Utility of anti-Sm, anti-RNP, anti-Ro/SS-A, and anti-La/SS-B (extractable nuclear antigens) detected by enzyme-linked immunosorbent assay for the diagnosis of systemic lupus erythematosus. Arthritis Rheum. 1996;39(6):1055-61.
    • (1996) Arthritis Rheum , vol.39 , Issue.6 , pp. 1055-1061
    • Sanchez-Guerrero, J.1    Lew, R.A.2    Fossel, A.H.3    Schur, P.H.4
  • 6
    • 33745617886 scopus 로고    scopus 로고
    • A Tlr7 translocation accelerates systemic autoimmunity in murine lupus
    • 16777955 10.1073/pnas.0603912103 1:CAS:528:DC%2BD28XmvVajtbY%3D
    • Subramanian S, Tus K, Li QZ, Wang A, Tian XH, Zhou J, et al. A Tlr7 translocation accelerates systemic autoimmunity in murine lupus. Proc Natl Acad Sci USA. 2006;103(26):9970-5.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.26 , pp. 9970-9975
    • Subramanian, S.1    Tus, K.2    Li, Q.Z.3    Wang, A.4    Tian, X.H.5    Zhou, J.6
  • 7
    • 22944490869 scopus 로고    scopus 로고
    • Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus
    • 16027240 10.1084/jem.20050338 1:CAS:528:DC%2BD2MXmsVKhtL8%3D
    • Christensen SR, Kashgarian M, Alexopoulou L, Flavell RA, Akira S, Shlomchik MJ. Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus. J Exp Med. 2005;202(2):321-31.
    • (2005) J Exp Med , vol.202 , Issue.2 , pp. 321-331
    • Christensen, S.R.1    Kashgarian, M.2    Alexopoulou, L.3    Flavell, R.A.4    Akira, S.5    Shlomchik, M.J.6
  • 8
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • 11477402 10.1038/90609 1:CAS:528:DC%2BD3MXlslGjtLs%3D
    • Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol. 2001;2(8):675-80.
    • (2001) Nat Immunol , vol.2 , Issue.8 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 9
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • 20303872 10.1016/j.cell.2010.01.022 1:CAS:528:DC%2BC3cXlsVSgu74%3D
    • Takeuchi O, Akira S. Pattern recognition receptors and inflammation. Cell. 2010;140(6):805-20.
    • (2010) Cell , vol.140 , Issue.6 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 10
    • 65649108429 scopus 로고    scopus 로고
    • The critical role of Toll-like receptor signaling pathways in the induction and progression of autoimmune diseases
    • 19355917 10.2174/156652409787847137 1:CAS:528:DC%2BD1MXktlant7c%3D
    • Li M, Zhou Y, Feng G, Su SB. The critical role of Toll-like receptor signaling pathways in the induction and progression of autoimmune diseases. Curr Mol Med. 2009;9(3):365-74.
    • (2009) Curr Mol Med , vol.9 , Issue.3 , pp. 365-374
    • Li, M.1    Zhou, Y.2    Feng, G.3    Su, S.B.4
  • 11
    • 36048962438 scopus 로고    scopus 로고
    • Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation
    • 17997333 10.1016/j.immuni.2007.09.009 1:CAS:528:DC%2BD2sXhsVWjurjP
    • Deane JA, Pisitkun P, Barrett RS, Feigenbaum L, Town T, Ward JM, et al. Control of toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation. Immunity. 2007;27(5):801-10.
    • (2007) Immunity , vol.27 , Issue.5 , pp. 801-810
    • Deane, J.A.1    Pisitkun, P.2    Barrett, R.S.3    Feigenbaum, L.4    Town, T.5    Ward, J.M.6
  • 12
    • 33748472865 scopus 로고    scopus 로고
    • Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus
    • 16973389 10.1016/j.immuni.2006.07.013 1:CAS:528:DC%2BD28XhtVOjtLzN
    • Christensen SR, Shupe J, Nickerson K, Kashgarian M, Flavell RA, Shlomchik MJ. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. Immunity. 2006;25(3):417-28.
    • (2006) Immunity , vol.25 , Issue.3 , pp. 417-428
    • Christensen, S.R.1    Shupe, J.2    Nickerson, K.3    Kashgarian, M.4    Flavell, R.A.5    Shlomchik, M.J.6
  • 13
    • 33750953650 scopus 로고    scopus 로고
    • Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: Implications for the induction and maintenance of the autoimmune process
    • 17075805 10.1002/art.22197 1:CAS:528:DC%2BD28Xht12mtLfN
    • Papadimitraki ED, Choulaki C, Koutala E, Bertsias G, Tsatsanis C, Gergianaki I, et al. Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune process. Arthritis Rheum. 2006;54(11):3601-11.
    • (2006) Arthritis Rheum , vol.54 , Issue.11 , pp. 3601-3611
    • Papadimitraki, E.D.1    Choulaki, C.2    Koutala, E.3    Bertsias, G.4    Tsatsanis, C.5    Gergianaki, I.6
  • 14
    • 43349094856 scopus 로고    scopus 로고
    • Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus
    • 18373699 10.1111/j.1365-2249.2008.03646.x 1:CAS:528:DC%2BD1cXnvVOitb8%3D
    • Komatsuda A, Wakui H, Iwamoto K, Ozawa M, Togashi M, Masai R, et al. Up-regulated expression of Toll-like receptors mRNAs in peripheral blood mononuclear cells from patients with systemic lupus erythematosus. Clin Exp Immunol. 2008;152(3):482-7.
    • (2008) Clin Exp Immunol , vol.152 , Issue.3 , pp. 482-487
    • Komatsuda, A.1    Wakui, H.2    Iwamoto, K.3    Ozawa, M.4    Togashi, M.5    Masai, R.6
  • 15
    • 38649102170 scopus 로고    scopus 로고
    • Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus
    • 10.1093/rheumatology/kem327 1:CAS:528:DC%2BD1cXht1Shsb4%3D
    • Nakano S, Morimoto S, Suzuki J, Nozawa K, Amano H, Tokano Y, et al. Role of pathogenic auto-antibody production by Toll-like receptor 9 of B cells in active systemic lupus erythematosus. Rheumatology (Oxford). 2008;47(2):145-9.
    • (2008) Rheumatology (Oxford) , vol.47 , Issue.2 , pp. 145-149
    • Nakano, S.1    Morimoto, S.2    Suzuki, J.3    Nozawa, K.4    Amano, H.5    Tokano, Y.6
  • 16
    • 77958119141 scopus 로고    scopus 로고
    • Gene expression profiles in a rabbit model of systemic lupus erythematosus autoantibody production
    • 20817871 10.4049/jimmunol.1001254 1:CAS:528:DC%2BC3cXhtFyis77F
    • Rai G, Ray S, Milton J, Yang J, Ren P, Lempicki R, et al. Gene expression profiles in a rabbit model of systemic lupus erythematosus autoantibody production. J Immunol. 2010;185(7):4446-56.
    • (2010) J Immunol , vol.185 , Issue.7 , pp. 4446-4456
    • Rai, G.1    Ray, S.2    Milton, J.3    Yang, J.4    Ren, P.5    Lempicki, R.6
  • 17
    • 84879205085 scopus 로고    scopus 로고
    • A rabbit model of systemic lupus erythematosus, useful for studies of neuropsychiatric SLE
    • H. Almoallim (eds) InTech Croatia
    • Mage RG, Rai G. A rabbit model of systemic lupus erythematosus, useful for studies of neuropsychiatric SLE. In: Almoallim H, editor. Systemic lupus erythematosus. Croatia: InTech; 2012. p. 201-16.
    • (2012) Systemic Lupus Erythematosus , pp. 201-216
    • Mage, R.G.1    Rai, G.2
  • 18
    • 0031229830 scopus 로고    scopus 로고
    • Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus
    • 9324032 10.1002/art.1780400928 1:STN:280:DyaK2svmsVaisw%3D%3D
    • Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1997;40(9):1725.
    • (1997) Arthritis Rheum , vol.40 , Issue.9 , pp. 1725
    • Hochberg, M.C.1
  • 19
    • 0036158415 scopus 로고    scopus 로고
    • Systemic lupus erythematosus disease activity index 2000
    • 11838846
    • Gladman DD, Ibañez D, Urowitz MB. Systemic lupus erythematosus disease activity index 2000. J Rheumatol. 2002;29(2):288-91.
    • (2002) J Rheumatol , vol.29 , Issue.2 , pp. 288-291
    • Gladman, D.D.1    Ibañez, D.2    Urowitz, M.B.3
  • 20
    • 77953502765 scopus 로고    scopus 로고
    • Human CD141+ (BDCA-3) + dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens
    • 20479116 10.1084/jem.20092140 1:CAS:528:DC%2BC3cXns1Snurw%3D
    • Jongbloed SL, Kassianos AJ, McDonald KJ, Clark GJ, Ju X, Angel CE, et al. Human CD141+ (BDCA-3) + dendritic cells (DCs) represent a unique myeloid DC subset that cross-presents necrotic cell antigens. J Exp Med. 2010;207(6):1247-60.
    • (2010) J Exp Med , vol.207 , Issue.6 , pp. 1247-1260
    • Jongbloed, S.L.1    Kassianos, A.J.2    McDonald, K.J.3    Clark, G.J.4    Ju, X.5    Angel, C.E.6
  • 21
    • 79952234401 scopus 로고    scopus 로고
    • Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-alpha-producing and partially matured phenotype
    • 21339641 10.1172/JCI44960
    • O'Brien M, Manches O, Sabado RL, Baranda SJ, Wang Y, Marie I, et al. Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-alpha-producing and partially matured phenotype. J Clin Invest. 2011;121(3):1088-101.
    • (2011) J Clin Invest , vol.121 , Issue.3 , pp. 1088-1101
    • O'Brien, M.1    Manches, O.2    Sabado, R.L.3    Baranda, S.J.4    Wang, Y.5    Marie, I.6
  • 22
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • 942051 10.1016/0003-2697(76)90527-3 1:CAS:528:DyaE28XksVehtrY%3D
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248-54.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 23
    • 33745168605 scopus 로고    scopus 로고
    • Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication
    • 16709748 10.1126/science.1124978 1:CAS:528:DC%2BD28XlsFeqtb4%3D
    • Pisitkun P, Deane JA, Difilippantonio MJ, Tarasenko T, Satterthwaite AB, Bolland S. Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication. Science. 2006;312(5780):1669-72.
    • (2006) Science , vol.312 , Issue.5780 , pp. 1669-1672
    • Pisitkun, P.1    Deane, J.A.2    Difilippantonio, M.J.3    Tarasenko, T.4    Satterthwaite, A.B.5    Bolland, S.6
  • 24
    • 1242307814 scopus 로고    scopus 로고
    • B cell abnormalities in systemic lupus erythematosus
    • 15180894 10.1186/ar1009
    • Grammer AC, Lipsky PE. B cell abnormalities in systemic lupus erythematosus. Arthritis Res Ther. 2003;5 Suppl 4:S22-7.
    • (2003) Arthritis Res Ther , vol.5 , Issue.SUPPL. 4 , pp. 22-27
    • Grammer, A.C.1    Lipsky, P.E.2
  • 25
    • 0037061453 scopus 로고    scopus 로고
    • Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
    • 11948342 10.1038/416603a 1:CAS:528:DC%2BD38XjtFahur8%3D
    • Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature. 2002;416(6881):603-7.
    • (2002) Nature , vol.416 , Issue.6881 , pp. 603-607
    • Leadbetter, E.A.1    Rifkin, I.R.2    Hohlbaum, A.M.3    Beaudette, B.C.4    Shlomchik, M.J.5    Marshak-Rothstein, A.6
  • 26
    • 27744444832 scopus 로고    scopus 로고
    • RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement
    • 16260486 10.1084/jem.20050630 1:CAS:528:DC%2BD2MXht1Sntr7F
    • Lau CM, Broughton C, Tabor AS, Akira S, Flavell RA, Mamula MJ, et al. RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. J Exp Med. 2005;202(9):1171-7.
    • (2005) J Exp Med , vol.202 , Issue.9 , pp. 1171-1177
    • Lau, C.M.1    Broughton, C.2    Tabor, A.S.3    Akira, S.4    Flavell, R.A.5    Mamula, M.J.6
  • 27
    • 77956135982 scopus 로고    scopus 로고
    • Monocyte and macrophage abnormalities in systemic lupus erythematosus
    • 10.1007/s00005-010-0093-y 1:CAS:528:DC%2BC3cXhtVKhtLrN
    • Li Y, Lee PY, Reeves WH. Monocyte and macrophage abnormalities in systemic lupus erythematosus. Arch Immunol Ther Exp (Warsz). 2010;58(5):355-64.
    • (2010) Arch Immunol Ther Exp (Warsz) , vol.58 , Issue.5 , pp. 355-364
    • Li, Y.1    Lee, P.Y.2    Reeves, W.H.3
  • 28
    • 82955233986 scopus 로고    scopus 로고
    • Neutrophils in the pathogenesis and manifestations of SLE
    • 21947176 10.1038/nrrheum.2011.132 1:CAS:528:DC%2BC3MXhsFKltL7F
    • Kaplan MJ. Neutrophils in the pathogenesis and manifestations of SLE. Nat Rev Rheumatol. 2011;7(12):691-9.
    • (2011) Nat Rev Rheumatol , vol.7 , Issue.12 , pp. 691-699
    • Kaplan, M.J.1
  • 29
    • 77952510795 scopus 로고    scopus 로고
    • Dendritic cells in systemic lupus erythematosus
    • 20367140 10.3109/08830181003602507 1:CAS:528:DC%2BC3cXkt1ajsL4%3D
    • Seitz HM, Matsushima GK. Dendritic cells in systemic lupus erythematosus. Int Rev Immunol. 2010;29(2):184-209.
    • (2010) Int Rev Immunol , vol.29 , Issue.2 , pp. 184-209
    • Seitz, H.M.1    Matsushima, G.K.2
  • 30
    • 33847634336 scopus 로고    scopus 로고
    • Toll-like receptor expression in lupus peripheral blood mononuclear cells
    • 17295441 1:CAS:528:DC%2BD2sXktVCju7o%3D
    • Migita K, Miyashita T, Maeda Y, Nakamura M, Yatsuhashi H, Kimura H, et al. Toll-like receptor expression in lupus peripheral blood mononuclear cells. J Rheumatol. 2007;34(3):493-500.
    • (2007) J Rheumatol , vol.34 , Issue.3 , pp. 493-500
    • Migita, K.1    Miyashita, T.2    Maeda, Y.3    Nakamura, M.4    Yatsuhashi, H.5    Kimura, H.6
  • 31
    • 84865413525 scopus 로고    scopus 로고
    • Aberrant CD40-induced NF-κB activation in human lupus B lymphocytes
    • 22952582 10.1371/journal.pone.0041644 1:CAS:528:DC%2BC38Xht1Olt7nK
    • Zhang W, Shi Q, Xu X, Chen H, Lin W, Zhang F, et al. Aberrant CD40-induced NF-κB activation in human lupus B lymphocytes. PLoS One. 2012;7(8):e41644.
    • (2012) PLoS One , vol.7 , Issue.8 , pp. 41644
    • Zhang, W.1    Shi, Q.2    Xu, X.3    Chen, H.4    Lin, W.5    Zhang, F.6
  • 32
    • 72849109689 scopus 로고    scopus 로고
    • Activation profile of intracellular mitogen-activated protein kinases in peripheral lymphocytes of patients with systemic lupus erythematosus
    • 19756990 10.1007/s10875-009-9318-4 1:CAS:528:DC%2BD1MXhsFWitLvK
    • Wong CK, Wong PT, Tam LS, Li EK, Chen DP, Lam CW. Activation profile of intracellular mitogen-activated protein kinases in peripheral lymphocytes of patients with systemic lupus erythematosus. J Clin Immunol. 2009;29(6):738-46.
    • (2009) J Clin Immunol , vol.29 , Issue.6 , pp. 738-746
    • Wong, C.K.1    Wong, P.T.2    Tam, L.S.3    Li, E.K.4    Chen, D.P.5    Lam, C.W.6
  • 33
    • 17144404177 scopus 로고    scopus 로고
    • IRF-7 is the master regulator of type-I interferon-dependent immune responses
    • 15800576 10.1038/nature03464 1:CAS:528:DC%2BD2MXivFCgurg%3D
    • Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, et al. IRF-7 is the master regulator of type-I interferon-dependent immune responses. Nature. 2005;434(7034):772-7.
    • (2005) Nature , vol.434 , Issue.7034 , pp. 772-777
    • Honda, K.1    Yanai, H.2    Negishi, H.3    Asagiri, M.4    Sato, M.5    Mizutani, T.6
  • 34
    • 0023601716 scopus 로고
    • Serum levels of interferons in patients with systemic lupus erythematosus
    • 2449306 1:STN:280:DyaL1c7js1ejtw%3D%3D
    • Kim T, Kanayama Y, Negoro N, Okamura M, Takeda T, Inoue T. Serum levels of interferons in patients with systemic lupus erythematosus. Clin Exp Immunol. 1987;70(3):562-9.
    • (1987) Clin Exp Immunol , vol.70 , Issue.3 , pp. 562-569
    • Kim, T.1    Kanayama, Y.2    Negoro, N.3    Okamura, M.4    Takeda, T.5    Inoue, T.6
  • 35
    • 77950805718 scopus 로고    scopus 로고
    • Interferon-alpha and interleukin-6 in SLE serum induce the differentiation and maturation of dendritic cells derived from CD34+ hematopoietic precursor cells
    • 20303780 10.1016/j.cyto.2010.02.017 1:CAS:528:DC%2BC3cXksVels7k%3D
    • Zhang R, Xing M, Ji X, Gu L, Yang X, Wang H, et al. Interferon-alpha and interleukin-6 in SLE serum induce the differentiation and maturation of dendritic cells derived from CD34+ hematopoietic precursor cells. Cytokine. 2010;50(2):195-203.
    • (2010) Cytokine , vol.50 , Issue.2 , pp. 195-203
    • Zhang, R.1    Xing, M.2    Ji, X.3    Gu, L.4    Yang, X.5    Wang, H.6
  • 36
    • 0344492212 scopus 로고    scopus 로고
    • Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus
    • 12604793 10.1073/pnas.0337679100 1:CAS:528:DC%2BD3sXitVaisb8%3D
    • Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Ortmann WA, Espe KJ, et al. Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. Proc Natl Acad Sci USA. 2003;100(5):2610-5.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.5 , pp. 2610-2615
    • Baechler, E.C.1    Batliwalla, F.M.2    Karypis, G.3    Gaffney, P.M.4    Ortmann, W.A.5    Espe, K.J.6
  • 37
    • 79957541792 scopus 로고    scopus 로고
    • Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells
    • 21624134 10.1186/1741-7015-9-65 1:CAS:528:DC%2BC3MXntVaisro%3D
    • Arasappan D, Tong W, Mummaneni P, Fang H, Amur S. Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells. BMC Med. 2011;9:65.
    • (2011) BMC Med , vol.9 , pp. 65
    • Arasappan, D.1    Tong, W.2    Mummaneni, P.3    Fang, H.4    Amur, S.5
  • 38
    • 34548438559 scopus 로고    scopus 로고
    • High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus
    • 17581626 10.1038/sj.gene.6364408 1:CAS:528:DC%2BD2sXpvFWgtL8%3D
    • Niewold TB, Hua J, Lehman TJ, Harley JB, Crow MK. High serum IFN-alpha activity is a heritable risk factor for systemic lupus erythematosus. Genes Immun. 2007;8(6):492-502.
    • (2007) Genes Immun , vol.8 , Issue.6 , pp. 492-502
    • Niewold, T.B.1    Hua, J.2    Lehman, T.J.3    Harley, J.B.4    Crow, M.K.5
  • 39
    • 33745030751 scopus 로고    scopus 로고
    • Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjogren's syndrome autoantigen-associated RNA
    • 16729300 10.1002/art.21893
    • Lovgren T, Eloranta ML, Kastner B, Wahren-Herlenius M, Alm GV, Ronnblom L. Induction of interferon-alpha by immune complexes or liposomes containing systemic lupus erythematosus autoantigen- and Sjogren's syndrome autoantigen-associated RNA. Arthritis Rheum. 2006;54(6):1917-27.
    • (2006) Arthritis Rheum , vol.54 , Issue.6 , pp. 1917-1927
    • Lovgren, T.1    Eloranta, M.L.2    Kastner, B.3    Wahren-Herlenius, M.4    Alm, G.V.5    Ronnblom, L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.