Intracellular fate of carbon nanotubes inside murine macrophages: PH-dependent detachment of iron catalyst nanoparticles

Particle and Fibre Toxicology

Volumn 10, Issue 1, 2013, Pages

  Bussy, Cyrill ^a,b,g   Paineau, Erwan ^b   Cambedouzou, Julien ^b,h   Brun, Nathalie ^b   Mory, Claudie ^b   Fayard, Barbara ^b,c   Salomé, Murielle ^c   Pinault, Mathieu ^d   Huard, Mickaël ^b   Belade, Esther ^a   Armand, Lucie ^a   Boczkowski, Jorge ^a,e,f   Launois, Pascale ^b   Lanone, Sophie ^a,f  

^a FACULTÉ DE MÉDECINE   (France)

^b UNIVERSITÉ PARIS SUD   (France)

^c EUROPEAN SYNCHROTRON RADIATION FACILITY   (France)

^d Centre National de la Recherche Scientifique   (France)

^e HENRI MONDOR HOSPITAL   (France)

^f CENTRE HOSPITALIER INTERCOMMUNAL DE CRÉTEIL   (France)

^g UNIVERSITY OF LONDON   (United Kingdom)

^h DIF   (France)

Author keywords

Carbon nanotubes; Degradation; Iron catalyst nanoparticles; Lysosome acidification; Toxicity

Indexed keywords

IRON NANOPARTICLE; NANOMATERIAL; NANOPARTICLE; SINGLE WALLED NANOTUBE; UNCLASSIFIED DRUG;

ACIDIFICATION; ANIMAL CELL; ARTICLE; BIOTRANSFORMATION; CATALYST; CELL NUCLEUS; CELL PROTECTION; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; ELECTRON ENERGY LOSS SPECTROSCOPY; HIGH ANGLE ANNULAR DARK FIELD TRANSMISSION ELECTRON MICROSCOPY; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; INTERNALIZATION; LYSOSOME; MACROPHAGE; MICRO X RAY FLUORESCENCE MAPPING; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; STRUCTURE ANALYSIS; SYNCHROTRON RADIATION; TRANSMISSION ELECTRON MICROSCOPY; X RAY DIFFRACTION; X RAY FLUORESCENCE;

ANIMALS; CATHEPSIN B; CELL LINE; HYDROGEN-ION CONCENTRATION; IRON COMPOUNDS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; LYSOSOMES; MACROLIDES; MACROPHAGES; METAL NANOPARTICLES; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; NANOTUBES, CARBON; SPECTROMETRY, X-RAY EMISSION; SPECTROSCOPY, ELECTRON ENERGY-LOSS; SYNCHROTRONS; X-RAY DIFFRACTION;

MURINAE;

EID: 84879218488     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-10-24     Document Type: Article

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