Adaptations of vertebrate neurons to hypoxia and anoxia: Maintaining critical Ca2+ concentrations

Journal of Experimental Biology

Volumn 201, Issue 8, 1998, Pages 1141-1152

  Bickler, Philip E ^a   Buck, Leslie T ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

Anoxia; Ca2+; Chrysemys picta belli; Hypoxia; Neuron; Turtle; Vertebrate

Indexed keywords

CALCIUM;

ADAPTATION; ANIMAL; ARTICLE; CELL HYPOXIA; METABOLISM; NERVE CELL; PHYSIOLOGY; VERTEBRATE;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CALCIUM; CELL HYPOXIA; NEURONS; VERTEBRATES;

ANIMALIA; CHRYSEMYS PICTA; MAMMALIA; TESTUDINES; VERTEBRATA;

EID: 0032052237     PISSN: 00220949     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. ADOLPH, E. (1948). Tolerance to cold and anoxia in infant rats. Am. J. Physiol. 155, 366-377.
2. ASCHER, P. AND NOWAK, L. (1987). Electrophysiological studies of NMDA receptors. Trends neurol. Sci. 10, 284-288.
3. BARTRUP, J. T. AND STONE, T. W. (1990). Activation of NMDA receptor-coupled channels suppresses the inhibitory action of adenosine on hippocampal slices. Brain Res. 530, 330-334.
4. BICKLER, P. E. (1992). Cerebral anoxia tolerance in turtles: regulation of intracellular calcium and pH. Am. J. Physiol. 263, R1298-R1302.
5. BICKLER, P. E., GALLEGO, S. M. AND HANSEN, B. M. (1993). Developmental changes in intracellular calcium regulation in rat cerebral cortex during hypoxia. J. cereb. Blood Flow Metab. 13, 811-819.
6. BICKLER, P. E. AND HANSEN, B. M. (1994). Causes of calcium accumulation in rat cortical brain slices during hypoxia and ischemia: role of ion channels and membrane damage. Brain Res. 665, 269-276.
7. BICKLER, P. AND HANSEN, B. (1997). Hypoxia-tolerant neonatal CA1 neurons: Relationship of survival to evoked glutamate release and glutamate receptor-mediated calcium changes in hippocampal slices. Dev. Brain Res. (in press).
8. BUCK, L. AND BICKLER, P. (1995). Role of adenosine in NMDA receptor modulation in the cerebral cortex of an anoxia-tolerant turtle (Chrysemys picta belli). J. exp. Biol. 198, 1621-1628.
9. BUCK, L. AND BICKLER, P. (1998). Adenosine and anoxia reduce N-methyl-D-aspartate receptor open probability in turtle cerebrocortex. J. exp. Biol. 201, 289-297.
10. BURKE, S. P. AND NADLER, J. V. (1988). Regulation of glutamate and aspartate release from slices of the hippocampal CA1 area: effects of adenosine and baclofen. J. Neurochem. 51, 1541-1551.
11. CERNE, R., RUSIN, K. I. AND RANDIC, M. (1993). Enhancement of the N-methyl-D-aspartate response in spinal dorsal horn neurons by cyclic AMP-dependent protein kinase. Neurosci. Lett. 161, 124-128.
12. CHIH, C., ROSENTHAL, M. AND SICK, T. (1989). Ion leakage is reduced during anoxia in turtle brain: a potential survival strategy. Am. J. Physiol. 257, R1562-R1564.
13. CHOI, D. W. (1992). Excitotoxic cell death. J. Neurobiol. 23, 1261-1276.
14. CHOI, D. W. (1995). Calcium: still center stage in hypoxic-ischemic neuronal death. Trends Neurosci. 18, 58-60.
15. CSERR, H., DEPASQUALE, M. AND JACKSON, D. (1988). Brain and cerebrospinal fluid composition after long-term anoxia in diving turtles. Am. J. Physiol. 255, R338-R343.
16. DE MENDONCA, A. AND RIBIERO, J. A. (1993). Adenosine inhibits NMDA receptor-mediated excitatory postsynaptic potential in the hippocampus. Brain Res. 606, 351-356.
17. DE MENDONCA, A., SEBASTIAO, A. M. AND RIBIERO, J. A. (1995). Inhibition of NMDA-mediated currents in isolated rat hippocampal neurones by adenosine A1 receptor activation. Neuroreport 6, 1097-1100.
18. DUFFY, T. E., KOHLE, S. J. AND VANNUCCI, R. C. (1975). Carbohydrate and energy metabolism in perinatal rat brain: relation to survival in anoxia. J. Neurochem. 24, 271-276.
19. DUNWIDDIE, T. V. (1985). The physiological role of adenosine in the central nervous system. Int. Rev. Biochem. 27, 63-139.
20. EDWARDS, R., LUTZ, P. AND BADEN, D. (1989). Relationship between energy expenditure and ion channel function in the rat and turtle brain. Am. J. Physiol. 255, R1345-R1359.
21. ELSE, P. (1991). Oxygen consumption and sodium pump thermogenesis in a developing mammal. Am. J. Physiol. 261, R1575-R1578.
22. FAZEKAS, J., ALEXANDER, F. AND HIMWICH, H. (1941). Tolerance of the newborn to anoxia. Am. J. Physiol. 134, 281-287.
23. FROHNWEISER, B., WEIGL, L. AND SCHREIBMAYER, W. (1995). Modulation of cardiac sodium channel isoform by cyclic-AMP-dependent protein kinase does not depend on phosphorylation of serine-1504 in the cytosolic loop interconnecting transmembrane domain-III and domain-IV. Pflügers arch. 430, 751-753.
24. GERBER, U., GREENE, R. W., HAAS, H. L. AND STEVENS, D. R. (1989). Characterization of inhibition mediated by adenosine in the hippocampus of the rat in vitro. J. Physiol., Lond. 417, 567-578.
25. HANSEN, A. (1985). Extracellular potassium concentration in juvenile and adult brain cortex during anoxia. Acta physiol. scand. 99, 412-428.
26. HOCHACHKA, P. (1986). Defense strategies against hypoxia and hypothermia. Science 231, 234-241.
27. HOCHACHKA, P., BUCK, L., DOLL, C. AND LAND, S. (1996). Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack. Proc. natn. Acad. Sci. U.S.A. 93, 9493-9498.
28. + channels during anoxia: major differences between rat (newborn and adult) and turtle neurons. J. Physiol., Lond. 448, 599-612.
29. + gradient dissipation during anoxia. J. exp. Biol. 198, 2575-2580.
30. KORNAU, H. C., SCHENKER, L. T., KENNEDY, M. B. AND SEEBURG, P. H. (1995). Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269, 1737-1740.
31. 2+-dependent phosphate. Nature 369, 235-239.
32. LIPTON, P. AND LOEBNER, D. (1990). Mechanisms of intracellular calcium accumulation in the CA1 region of rat hippocampus during anoxia in vivo. Stroke 21, 60-64.
33. LUTZ, P. (1992). Mechanisms for anoxic survival in the vertebrate brain. A. Rev. Physiol. 54, 601-618.
34. LUTZ, P. AND NILSSON, G. (1997). Contrasting strategies for anoxic brain survival - glycolysis up or down. J. exp. Biol. 200, 411-419.
35. MOGUL, D. J., ADAMS, M. E. AND FOX, A. P. (1993). Differential activation of adenosine receptors decreases N-type but potentiates P-type current in hippocampal CA3 neurons. Neuron 10, 327-334.
36. + channel alpha subunit by cyclic AMP dependent protein kinase and phosphoprotein phosphatases. J. biol. Chem. 268, 27355-27362.
37. MYNLIEFF, M. AND BEAM, K. G. (1994). Adenosine acting at an A1 receptor decreases N-type calcium current in mouse motoneurons. J. Neurosci. 14, 3628-3634.
38. NILSSON, G. (1993). Neurotransmitters and anoxia resistance: Comparative physiological and evolutionary perspectives. In Surviving Hypoxia: Mechanisms of Control and Adaptation (ed. P. Hochachka, P. Lutz, T. Sick, M. Rosenthal and G. van den Thillart), pp. 401-413. Boca Raton, FL: CRC Press.
39. NILSSON, G. AND LUTZ, P. (1992). Adenosine release in anoxic turtle brain as a mechanism for anoxic survival. J. exp. Biol. 162, 345-351.
40. PEK, M. AND LUTZ, P. (1997). Role for adenosine in channel arrest in the anoxic turtle brain. J. exp. Biol. 200, 1913-1917.
41. PEREZ-PINZON, M., LUTZ, P., SICK, T. AND ROSENTHAL, M. (1993). Adenosine, a 'retaliatory' metabolite, promotes anoxia tolerance in turtle brain. J. cereb. Blood Flow Metab. 13, 728-732.
42. PEREZ-PINZON, M., ROSENTHAL, M., SICK, T., LUTZ, P., PABLO, J. AND MASH, D. (1992). Down-regulation of sodium channels during anoxia: a putative survival strategy of turtle brain. Am. J. Physiol. 262, R712-R715.
43. REYNOLDS, J. AND BREIN, J. (1992). Ontogeny of glutamate and gamma-aminobutyric acid release in the hippocampus of the guinea pig. J. dev. Physiol. 18, 243-252.
44. RUDOLPHI, K. A., SCHUBERT, P., PARKINSON, F. E. AND FREDHOLM, B. B. (1992). Adenosine and brain ischemia. Cerebrovasc. Brain Metab. Rev. 4, 346-369.
45. 2+ currents and synaptic transmission in cultured rat hippocampal pyramidal neurons. J. Physiol., Lond. 435, 373-393.
46. SICK, T., PEREZ-PINZON, M., LUTZ, P. AND ROSENTHAL, M. (1993). Maintaining coupled metabolism and membrane function in anoxic brain: A comparison between the turtle and the rat. In Surviving Hypoxia: Mechanisms of Control and Adaptation (ed. P. Hochachka, P. Lutz, T. Sick, M. Rosenthal and G. van den Thillart), pp. 351-364. Boca Raton, FL: CRC Press.
47. SIESJÖ, B. K. (1992). Pathophysiology and treatment of focal cerebral ischemia. II. Mechanisms of damage and treatment. J. Neurosurg. 77, 337-354.
48. SZATKOWSKI, M. AND ATTWELL, D. (1994). Triggering and execution of neuronal death in brain ischemia: two phases of glutamate release by different mechanisms. Trends Neurosci. 17, 359-365.
49. TINGLEY, W., ROCHE, K. W., THOMPSON, A. K. AND HUGANIR, R. L. (1993). Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain. Nature 364, 70-73.
50. ULTSCH, G. AND JACKSON, D. (1982). Long-term submergence at 3°C ot the turtle Chrysemys picta belli, in normoxic and severely hypoxic water. I. Survival, gas exchange and acid-base status. J. exp. Biol. 96, 11-28.
51. WANG, Y. T. AND SALTER, M. W. (1994). Regulation of NMDA receptors by tyrosine kinases and phosphatases. Nature 369, 233-235.
52. WU, L. AND SAGGAU, P. (1994). Adenosine inhibits evoked synaptic transmission primarily by reducing presynaptic calcium influx in area CA1 of hippocampus. Neuron 12, 1139-1148.
53. XIA, Y. AND HADDAD, G. (1991). Major differences in CNS sulfonylurea receptor distribution between the rat (newborn, adult) and turtle. J. comp. Neurol. 314, 278-289.
54. 2+ channels by adenosine autoreceptors. Nature 365, 256-258.