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Volumn 8, Issue 6, 2013, Pages

Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BETAMETHASONE; BUDESONIDE; DEXAMETHASONE; FENOTEROL; FLUDROCORTISONE; FLUMETASONE; GLUCOCORTICOID; HIGH MOBILITY GROUP B1 PROTEIN; HYDROCORTISONE; I KAPPA B; IMIPENEM; INDAPAMIDE; INDINAVIR; MESSENGER RNA; METHYLPREDNISOLONE; MIFEPRISTONE; MITOGEN ACTIVATED PROTEIN KINASE; ORCIPRENALINE; PARTHENOLIDE; PREDNISOLONE; PROPRANOLOL; RITODRINE; SALBUTAMOL; TOLNAFTATE; TRIAMCINOLONE; TUMOR NECROSIS FACTOR ALPHA; TYLOXAPOL; UNINDEXED DRUG;

EID: 84879129201     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0065994     Document Type: Article
Times cited : (29)

References (31)
  • 2
    • 84859440796 scopus 로고    scopus 로고
    • HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease
    • Harris HE, Andersson U, Pisetsky D, (2012) HMGB1: a multifunctional alarmin driving autoimmune and inflammatory disease. Nat Rev Rheumatol 8: 195-202.
    • (2012) Nat Rev Rheumatol , vol.8 , pp. 195-202
    • Harris, H.E.1    Andersson, U.2    Pisetsky, D.3
  • 3
    • 79953066407 scopus 로고    scopus 로고
    • HMGB1 is a therapeutic target for sterile inflammation and infection
    • Andersson U, Tracey KJ, (2011) HMGB1 is a therapeutic target for sterile inflammation and infection. Annu Rev Immunol 29: 139-62.
    • (2011) Annu Rev Immunol , vol.29 , pp. 139-162
    • Andersson, U.1    Tracey, K.J.2
  • 4
    • 78650067155 scopus 로고    scopus 로고
    • High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activity
    • Evankovich J, Cho SW, Zhang R, Cardinal J, Dhupar R, et al. (2010) High mobility group box 1 release from hepatocytes during ischemia and reperfusion injury is mediated by decreased histone deacetylase activity. J Biol Chem 285: 39888-97.
    • (2010) J Biol Chem , vol.285 , pp. 39888-39897
    • Evankovich, J.1    Cho, S.W.2    Zhang, R.3    Cardinal, J.4    Dhupar, R.5
  • 5
    • 84865511926 scopus 로고    scopus 로고
    • Novel role of PKR in inflammasome activation and HMGB1 release
    • Lu B, Nakamura T, Inouye K, Li J, Tang Y, et al. (2012) Novel role of PKR in inflammasome activation and HMGB1 release. Nature 488: 670-4.
    • (2012) Nature , vol.488 , pp. 670-674
    • Lu, B.1    Nakamura, T.2    Inouye, K.3    Li, J.4    Tang, Y.5
  • 6
    • 67650493786 scopus 로고    scopus 로고
    • Novel HMGB1-inhibiting therapeutic agents for experimental sepsis
    • Wang H, Ward MF, Sama AE, (2009) Novel HMGB1-inhibiting therapeutic agents for experimental sepsis. Shock 32: 348-57.
    • (2009) Shock , vol.32 , pp. 348-357
    • Wang, H.1    Ward, M.F.2    Sama, A.E.3
  • 7
    • 74449089862 scopus 로고    scopus 로고
    • Targeting HMGB1 in inflammation
    • Yang H, Tracey KJ, (2010) Targeting HMGB1 in inflammation. Biochim Biophys Acta 1799: 149-56.
    • (2010) Biochim Biophys Acta , vol.1799 , pp. 149-156
    • Yang, H.1    Tracey, K.J.2
  • 8
    • 0037125985 scopus 로고    scopus 로고
    • Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation
    • Ulloa L, Ochani M, Yang H, Tanovic M, Halperin D, et al. (2002) Ethyl pyruvate prevents lethality in mice with established lethal sepsis and systemic inflammation. Proc Natl Acad Sci USA 99: 12351-6.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12351-12356
    • Ulloa, L.1    Ochani, M.2    Yang, H.3    Tanovic, M.4    Halperin, D.5
  • 9
    • 34547105307 scopus 로고    scopus 로고
    • Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus
    • Ditsworth D, Zong WX, Thompson CB, (2007) Activation of poly(ADP)-ribose polymerase (PARP-1) induces release of the pro-inflammatory mediator HMGB1 from the nucleus. J Biol Chem 282: 17845-54.
    • (2007) J Biol Chem , vol.282 , pp. 17845-17854
    • Ditsworth, D.1    Zong, W.X.2    Thompson, C.B.3
  • 10
    • 77449083458 scopus 로고    scopus 로고
    • Alpha7 cholinergic-agonist prevents systemic inflammation and improves survival during resuscitation
    • Cai B, Chen F, Ji Y, Kiss L, de Jonge WJ, et al. (2009) Alpha7 cholinergic-agonist prevents systemic inflammation and improves survival during resuscitation. J Cell Mol Med 13: 3774-85.
    • (2009) J Cell Mol Med , vol.13 , pp. 3774-3785
    • Cai, B.1    Chen, F.2    Ji, Y.3    Kiss, L.4    de Jonge, W.J.5
  • 11
    • 77956624951 scopus 로고    scopus 로고
    • Immunomodulatory drugs regulate HMGB1 release from activated human monocytes
    • Schierbeck H, Wähämaa H, Andersson U, Harris HE, (2010) Immunomodulatory drugs regulate HMGB1 release from activated human monocytes. Mol Med 16: 343-51.
    • (2010) Mol Med , vol.16 , pp. 343-351
    • Schierbeck, H.1    Wähämaa, H.2    Andersson, U.3    Harris, H.E.4
  • 12
    • 84866378556 scopus 로고    scopus 로고
    • Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. J Exp Med
    • Venereau E, Casalgrandi M, Schiraldi M, Antoine DJ, Cattaneo A, et al. (2012) Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release. J Exp Med. 209: 1519-28.
    • (2012) , vol.209 , pp. 1519-1528
    • Venereau, E.1    Casalgrandi, M.2    Schiraldi, M.3    Antoine, D.J.4    Cattaneo, A.5
  • 13
    • 84860862890 scopus 로고    scopus 로고
    • Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1). Mol Med
    • Yang H, Lundbäck P, Ottosson L, Erlandsson-Harris H, Venereau E, et al. (2012) Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1). Mol Med. 18: 250-9.
    • (2012) , vol.18 , pp. 250-259
    • Yang, H.1    Lundbäck, P.2    Ottosson, L.3    Erlandsson-Harris, H.4    Venereau, E.5
  • 14
    • 84878180533 scopus 로고    scopus 로고
    • Signaling of High Mobility Group Box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14
    • in press
    • Kim S, Kim SY, Pribis JP, Lotze M, Mollen KP, et al. (2013) Signaling of High Mobility Group Box 1 (HMGB1) through toll-like receptor 4 in macrophages requires CD14. Mol Med, in press.
    • (2013) Mol Med
    • Kim, S.1    Kim, S.Y.2    Pribis, J.P.3    Lotze, M.4    Mollen, K.P.5
  • 15
    • 77955403878 scopus 로고    scopus 로고
    • A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. Proc Natl Acad Sci USA
    • Yang H, Hreggvidsdottir HS, Palmblad K, Wang H, Ochani M, et al. (2010) A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release. Proc Natl Acad Sci USA. 107: 11942-11947.
    • (2010) , vol.107 , pp. 11942-11947
    • Yang, H.1    Hreggvidsdottir, H.S.2    Palmblad, K.3    Wang, H.4    Ochani, M.5
  • 16
    • 38449115536 scopus 로고    scopus 로고
    • Oxidant-induced cardiomyocyte injury: identification of the cytoprotective effect of a dopamine 1 receptor agonist using a cell-based high-throughput assay
    • Gero D, Modis K, Nagy N, Szoleczky P, Toth ZD, et al. (2007) Oxidant-induced cardiomyocyte injury: identification of the cytoprotective effect of a dopamine 1 receptor agonist using a cell-based high-throughput assay. Int J Mol Med 20: 749-61.
    • (2007) Int J Mol Med , vol.20 , pp. 749-761
    • Gero, D.1    Modis, K.2    Nagy, N.3    Szoleczky, P.4    Toth, Z.D.5
  • 17
    • 84874445236 scopus 로고    scopus 로고
    • Cell-based screening identifies paroxetine as an inhibitor of diabetic endothelial dysfunction
    • Gero D, Szoleczky P, Suzuki K, Modis K, Olah G, et al. (2013) Cell-based screening identifies paroxetine as an inhibitor of diabetic endothelial dysfunction. Diabetes 62: 953-64.
    • (2013) Diabetes , vol.62 , pp. 953-964
    • Gero, D.1    Szoleczky, P.2    Suzuki, K.3    Modis, K.4    Olah, G.5
  • 18
    • 11144268546 scopus 로고    scopus 로고
    • Antiretroviral drugs with adverse effects on adipocyte lipid metabolism and survival alter the expression and secretion of proinflammatory cytokines and adiponectin in vitro
    • Lagathu C, Bastard JP, Auclair M, Maachi M, Kornprobst M, et al. (2004) Antiretroviral drugs with adverse effects on adipocyte lipid metabolism and survival alter the expression and secretion of proinflammatory cytokines and adiponectin in vitro. Antivir Ther 9: 911-20.
    • (2004) Antivir Ther , vol.9 , pp. 911-920
    • Lagathu, C.1    Bastard, J.P.2    Auclair, M.3    Maachi, M.4    Kornprobst, M.5
  • 19
    • 0029835335 scopus 로고    scopus 로고
    • Tyloxapol inhibits NF-κB and cytokine release, scavenges HOCI, and reduces viscosity of cystic fibrosis sputum
    • Ghio AJ, Marshall BC, Diaz JL, Hasegawa T, Samuelson W, et al. (1996) Tyloxapol inhibits NF-κB and cytokine release, scavenges HOCI, and reduces viscosity of cystic fibrosis sputum. Am J Respir Crit Care Med 154: 783-8.
    • (1996) Am J Respir Crit Care Med , vol.154 , pp. 783-788
    • Ghio, A.J.1    Marshall, B.C.2    Diaz, J.L.3    Hasegawa, T.4    Samuelson, W.5
  • 20
    • 42049086558 scopus 로고    scopus 로고
    • Lidocaine down-regulates nuclear factor-κB signalling and inhibits cytokine production and T cell proliferation
    • Lahat A, Ben-Horin S, Lang A, Fudim E, Picard O, et al. (2008) Lidocaine down-regulates nuclear factor-κB signalling and inhibits cytokine production and T cell proliferation. Clin Exp Immunol 152: 320-7.
    • (2008) Clin Exp Immunol , vol.152 , pp. 320-327
    • Lahat, A.1    Ben-Horin, S.2    Lang, A.3    Fudim, E.4    Picard, O.5
  • 21
    • 0027530626 scopus 로고
    • Relative roles of CCAAT/Enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase
    • Park EA, Gurney AL, Nizielski SE, Hakimi P, Cao Z, et al. (1993) Relative roles of CCAAT/Enhancer-binding protein beta and cAMP regulatory element-binding protein in controlling transcription of the gene for phosphoenolpyruvate carboxykinase. J Biol Chem 268: 613-619.
    • (1993) J Biol Chem , vol.268 , pp. 613-619
    • Park, E.A.1    Gurney, A.L.2    Nizielski, S.E.3    Hakimi, P.4    Cao, Z.5
  • 22
    • 0036153433 scopus 로고    scopus 로고
    • Scientific rationale for inhaled combination therapy with long-acting beta2-agonists and corticosteroids
    • Barnes PJ, (2002) Scientific rationale for inhaled combination therapy with long-acting beta2-agonists and corticosteroids. Eur Respir J 19: 182-91.
    • (2002) Eur Respir J , vol.19 , pp. 182-191
    • Barnes, P.J.1
  • 23
    • 2342627250 scopus 로고    scopus 로고
    • Synergistic effect of dexamethasone and beta-adrenergic receptor agonists on the nerve growth factor gene transcription. Brain Res Mol Brain Res
    • Colangelo AM, Mallei A, Johnson PF, Mocchetti I, (2004) Synergistic effect of dexamethasone and beta-adrenergic receptor agonists on the nerve growth factor gene transcription. Brain Res Mol Brain Res. 124: 97-104.
    • (2004) , vol.124 , pp. 97-104
    • Colangelo, A.M.1    Mallei, A.2    Johnson, P.F.3    Mocchetti, I.4
  • 24
    • 0028851635 scopus 로고
    • The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system
    • Hori O, Brett J, Slattery T, Cao R, Zhang J, et al. (1995) The receptor for advanced glycation end products (RAGE) is a cellular binding site for amphoterin. Mediation of neurite outgrowth and co-expression of rage and amphoterin in the developing nervous system. J Biol Chem 270: 25752-61.
    • (1995) J Biol Chem , vol.270 , pp. 25752-25761
    • Hori, O.1    Brett, J.2    Slattery, T.3    Cao, R.4    Zhang, J.5
  • 25
    • 63149171602 scopus 로고    scopus 로고
    • CD24 and Siglec-10 selectively repress tissue damage-induced immune responses
    • Chen GY, Tang J, Zheng P, Liu Y, (2009) CD24 and Siglec-10 selectively repress tissue damage-induced immune responses. Science 323: 1722-1725.
    • (2009) Science , vol.323 , pp. 1722-1725
    • Chen, G.Y.1    Tang, J.2    Zheng, P.3    Liu, Y.4
  • 26
    • 70149084792 scopus 로고    scopus 로고
    • HMGB1 loves company
    • Bianchi ME, (2009) HMGB1 loves company. J Leukoc Biol 86: 573-576.
    • (2009) J Leukoc Biol , vol.86 , pp. 573-576
    • Bianchi, M.E.1
  • 27
    • 84986674938 scopus 로고
    • Hormones and resistance
    • Selye H, (1971) Hormones and resistance. J Pharm Sci 60: 1-28.
    • (1971) J Pharm Sci , vol.60 , pp. 1-28
    • Selye, H.1
  • 28
    • 35548958257 scopus 로고    scopus 로고
    • The catecholamine cytokine balance: interaction between the brain and the immune system
    • Szelenyi J, Vizi ES, (2007) The catecholamine cytokine balance: interaction between the brain and the immune system. Ann N Y Acad Sci 1113: 311-24.
    • (2007) Ann N Y Acad Sci , vol.1113 , pp. 311-324
    • Szelenyi, J.1    Vizi, E.S.2
  • 29
    • 66449111088 scopus 로고    scopus 로고
    • Reflex control of immunity
    • Tracey KJ, (2009) Reflex control of immunity. Nat Rev Immunol 9: 418-28.
    • (2009) Nat Rev Immunol , vol.9 , pp. 418-428
    • Tracey, K.J.1
  • 30
    • 0023922510 scopus 로고
    • Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor
    • Bertini R, Bianchi M, Ghezzi P, (1988) Adrenalectomy sensitizes mice to the lethal effects of interleukin 1 and tumor necrosis factor. J Exp Med 167: 1708-12.
    • (1988) J Exp Med , vol.167 , pp. 1708-1712
    • Bertini, R.1    Bianchi, M.2    Ghezzi, P.3
  • 31
    • 0031022127 scopus 로고    scopus 로고
    • Isoproterenol regulates tumour necrosis factor, interleukin-10, interleukin-6 and nitric oxide production and protects against the development of vascular hyporeactivity in endotoxaemia
    • Szabo C, Hasko G, Zingarelli B, Nemeth ZH, Salzman AL, et al. (1997) Isoproterenol regulates tumour necrosis factor, interleukin-10, interleukin-6 and nitric oxide production and protects against the development of vascular hyporeactivity in endotoxaemia. Immunology 90: 95-100.
    • (1997) Immunology , vol.90 , pp. 95-100
    • Szabo, C.1    Hasko, G.2    Zingarelli, B.3    Nemeth, Z.H.4    Salzman, A.L.5


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