Lidocaine down-regulates nuclear factor-κB signalling and inhibits cytokine production and T cell proliferation

Clinical and Experimental Immunology

Volumn 152, Issue 2, 2008, Pages 320-327

  Lahat, A ^a,b   Horin, S B ^a   Lang, A ^a   Fudim, E ^a   Picard, O ^a   Chowers, Y ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b SHEBA MEDICAL CENTER   (Israel)

Author keywords

Cytokine; Inflammation; Lidocaine; NF B; T cell

Indexed keywords

CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; LIDOCAINE; LIPOCORTIN 5; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ANTIINFLAMMATORY ACTIVITY; APOPTOSIS; ARTICLE; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LYMPHOCYTE PROLIFERATION; NORMAL HUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANESTHETICS, LOCAL; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; DOWN-REGULATION; HUMANS; IMMUNE TOLERANCE; INTERFERON TYPE II; INTERLEUKIN-2; JURKAT CELLS; LIDOCAINE; LYMPHOCYTE ACTIVATION; NF-KAPPA B; RNA, MESSENGER; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 42049086558     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2008.03636.x     Document Type: Article

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