메뉴 건너뛰기




Volumn 27, Issue 9, 2013, Pages 1375-1385

HIV exposed seronegative individuals show antibodies specifically recognizing native HIV envelope glycoprotein

Author keywords

Conformational epitopes; Natural antibodies; Protection; Soluble CD4 induced epitopes transmission

Indexed keywords

GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 140; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; VIRUS ENVELOPE PROTEIN;

EID: 84879121537     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0b013e32835fac08     Document Type: Article
Times cited : (15)

References (46)
  • 1
    • 0030582188 scopus 로고    scopus 로고
    • Global burden of the HIV pandemic
    • Quinn TC. Global burden of the HIV pandemic. Lancet 1996; 348:99-106.
    • (1996) Lancet , vol.348 , pp. 99-106
    • Quinn, T.C.1
  • 3
    • 33847390394 scopus 로고    scopus 로고
    • Microbicide drug candidates to prevent HIV infection
    • Balzarini J, Van Damme L. Microbicide drug candidates to prevent HIV infection. Lancet 2007; 369:787-797.
    • (2007) Lancet , vol.369 , pp. 787-797
    • Balzarini, J.1    Van Damme, L.2
  • 4
    • 33746555576 scopus 로고    scopus 로고
    • HIV/AIDS epidemiology, pathogenesis, prevention, and treatment
    • Simon V, Ho DD, Abdool Karim Q. HIV/AIDS epidemiology, pathogenesis, prevention, and treatment. Lancet 2006; 368: 489-504.
    • (2006) Lancet , vol.368 , pp. 489-504
    • Simon, V.1    Ho, D.D.2    Abdool Karim, Q.3
  • 5
    • 79551578453 scopus 로고    scopus 로고
    • Early events in sexual transmission of HIV and SIV and opportunities for interventions
    • Haase AT. Early events in sexual transmission of HIV and SIV and opportunities for interventions. Annu Rev Med 2011; 62:127-139.
    • (2011) Annu Rev Med , vol.62 , pp. 127-139
    • Haase, A.T.1
  • 6
    • 0035857959 scopus 로고    scopus 로고
    • Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda
    • Gray RH, Wawer MJ, Brookmeyer R, Sewankambo NK, Serwadda D, Wabwire-Mangen F, et al. Probability of HIV-1 transmission per coital act in monogamous, heterosexual, HIV-1-discordant couples in Rakai, Uganda. Lancet 2001; 357:1149-1153.
    • (2001) Lancet , vol.357 , pp. 1149-1153
    • Gray, R.H.1    Wawer, M.J.2    Brookmeyer, R.3    Sewankambo, N.K.4    Serwadda, D.5    Wabwire-Mangen, F.6
  • 9
    • 79959836609 scopus 로고    scopus 로고
    • Outcomes of a National Institute of Allergy and Infectious Diseases Workshop on understanding HIV-exposed but seronegative individuals
    • Young JM, Turpin JA, Musib R, Sharma OK. Outcomes of a National Institute of Allergy and Infectious Diseases Workshop on understanding HIV-exposed but seronegative individuals. AIDS Res Hum Retroviruses 2011; 27:737-743.
    • (2011) AIDS Res Hum Retroviruses , vol.27 , pp. 737-743
    • Young, J.M.1    Turpin, J.A.2    Musib, R.3    Sharma, O.K.4
  • 10
    • 55849146247 scopus 로고    scopus 로고
    • Potentially exposed but uninfected individuals produce cytotoxic and polyfunctional human immunodeficiency virus type 1-specific CD8(R) T-cell responses which can be defined to the epitope level
    • Erickson AL, Willberg CB, McMahan V, Liu A, Buchbinder SP, Grohskopf LA, et al. Potentially exposed but uninfected individuals produce cytotoxic and polyfunctional human immunodeficiency virus type 1-specific CD8(R) T-cell responses which can be defined to the epitope level. Clin Vaccine Immunol 2008; 15:1745-1748.
    • (2008) Clin Vaccine Immunol , vol.15 , pp. 1745-1748
    • Erickson, A.L.1    Willberg, C.B.2    McMahan, V.3    Liu, A.4    Buchbinder, S.P.5    Grohskopf, L.A.6
  • 12
    • 0035019983 scopus 로고    scopus 로고
    • CD8(R) lymphocytes respond to different HIV epitopes in seronegative and infected subjects
    • Kaul R, Dong T, Plummer FA, Kimani J, Rostron T, Kiama P, et al. CD8(R) lymphocytes respond to different HIV epitopes in seronegative and infected subjects. J Clin Invest 2001; 107:1303-1310.
    • (2001) J Clin Invest , vol.107 , pp. 1303-1310
    • Kaul, R.1    Dong, T.2    Plummer, F.A.3    Kimani, J.4    Rostron, T.5    Kiama, P.6
  • 13
    • 0035501152 scopus 로고    scopus 로고
    • New insights into HIV-1 specific cytotoxic T-lymphocyte responses in exposed, persistently seronegative Kenyan sex workers
    • Kaul R, Rowland-Jones SL, Kimani J, Fowke K, Dong T, Kiama P, et al. New insights into HIV-1 specific cytotoxic T-lymphocyte responses in exposed, persistently seronegative Kenyan sex workers. Immunol Lett 2001; 79:3-13.
    • (2001) Immunol Lett , vol.79 , pp. 3-13
    • Kaul, R.1    Rowland-Jones, S.L.2    Kimani, J.3    Fowke, K.4    Dong, T.5    Kiama, P.6
  • 14
    • 34948846696 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV) gag antigen-specific T-helper and granule-dependent CD8 T-cell activities in exposed but uninfected heterosexual partners of HIV type 1-infected individuals in North India
    • Pallikkuth S, Wanchu A, Bhatnagar A, Sachdeva RK, Sharma M. Human immunodeficiency virus (HIV) gag antigen-specific T-helper and granule-dependent CD8 T-cell activities in exposed but uninfected heterosexual partners of HIV type 1-infected individuals in North India. Clin Vaccine Immunol 2007; 14:1196-1202.
    • (2007) Clin Vaccine Immunol , vol.14 , pp. 1196-1202
    • Pallikkuth, S.1    Wanchu, A.2    Bhatnagar, A.3    Sachdeva, R.K.4    Sharma, M.5
  • 15
    • 77955496369 scopus 로고    scopus 로고
    • Low-level exposure to HIV induces virus-specific T cell responses and immune activation in exposed HIV-seronegative individuals
    • Restrepo C, Rallón NI, del Romero J, Rodríguez C, Hernando V, López M, et al. Low-level exposure to HIV induces virus-specific T cell responses and immune activation in exposed HIV-seronegative individuals. J Immunol 2010; 185:982-989.
    • (2010) J Immunol , vol.185 , pp. 982-989
    • Restrepo, C.1    Rallón, N.I.2    Del Romero, J.3    Rodríguez, C.4    Hernando, V.5    López, M.6
  • 16
    • 2942676472 scopus 로고    scopus 로고
    • Potent neutralizing serum immunoglobulin A (IgA) in human immunodeficiency virus type 2-exposed IgG-seronegative individuals
    • Lizeng Q, Nilsson C, Sourial S, Andersson S, Larsen O, Aaby P, et al. Potent neutralizing serum immunoglobulin A (IgA) in human immunodeficiency virus type 2-exposed IgG-seronegative individuals. J Virol 2004; 78:7016-7022.
    • (2004) J Virol , vol.78 , pp. 7016-7022
    • Lizeng, Q.1    Nilsson, C.2    Sourial, S.3    Andersson, S.4    Larsen, O.5    Aaby, P.6
  • 17
    • 33745906244 scopus 로고    scopus 로고
    • HIV-specific antibodies but not t-cell responses are associated with protection in seronegative partners of HIV-1-infected individuals in Cambodia
    • Nguyen M, Pean P, Lopalco L, Nouhin J, Phoung V, Ly N, et al. HIV-specific antibodies but not t-cell responses are associated with protection in seronegative partners of HIV-1-infected individuals in Cambodia. J Acquir Immune Defic Syndr 2006; 42:412-419.
    • (2006) J Acquir Immune Defic Syndr , vol.42 , pp. 412-419
    • Nguyen, M.1    Pean, P.2    Lopalco, L.3    Nouhin, J.4    Phoung, V.5    Ly, N.6
  • 19
    • 0344838486 scopus 로고    scopus 로고
    • Mucosal and systemic HIV-1-specific immunity in HIV-1-exposed but uninfected heterosexual men
    • Lo Caputo S, Trabattoni D, Vichi F, Piconi S, Lopalco L, Villa ML, et al. Mucosal and systemic HIV-1-specific immunity in HIV-1-exposed but uninfected heterosexual men. AIDS 2003; 17:531-539.
    • (2003) AIDS , vol.17 , pp. 531-539
    • Lo Caputo, S.1    Trabattoni, D.2    Vichi, F.3    Piconi, S.4    Lopalco, L.5    Villa, M.L.6
  • 21
    • 73649143882 scopus 로고    scopus 로고
    • Orally exposed uninfected individuals have systemic anti-HIV responses associating with partners' viral load
    • Hasselrot K, Bratt G, Hirbod T, Säberg P, Ehnlund M, Lopalco L, et al. Orally exposed uninfected individuals have systemic anti-HIV responses associating with partners' viral load. AIDS 2010; 24:35-43.
    • (2010) AIDS , vol.24 , pp. 35-43
    • Hasselrot, K.1    Bratt, G.2    Hirbod, T.3    Säberg, P.4    Ehnlund, M.5    Lopalco, L.6
  • 22
    • 0034653980 scopus 로고    scopus 로고
    • CCR5-reactive antibodies in seronegative partners of HIV-seropositive individuals down-modulate surface CCR5 in vivo and neutralize the infectivity of R5 strains of HIV-1 In vitro
    • Lopalco L, Barassi C, Pastori C, Longhi R, Burastero SE, Tambussi G, et al. CCR5-reactive antibodies in seronegative partners of HIV-seropositive individuals down-modulate surface CCR5 in vivo and neutralize the infectivity of R5 strains of HIV-1 In vitro. J Immunol 2000; 164:3426-3433.
    • (2000) J Immunol , vol.164 , pp. 3426-3433
    • Lopalco, L.1    Barassi, C.2    Pastori, C.3    Longhi, R.4    Burastero, S.E.5    Tambussi, G.6
  • 23
    • 79951754740 scopus 로고    scopus 로고
    • Immunization with HIV-1 gp41 subunit virosomes induces mucosal antibodies protecting nonhuman primates against vaginal SHIV challenges
    • Bomsel M, Tudor D, Drillet AS, Alfsen A, Ganor Y, Roger MG, et al. Immunization with HIV-1 gp41 subunit virosomes induces mucosal antibodies protecting nonhuman primates against vaginal SHIV challenges. Immunity 2011; 34:269-280.
    • (2011) Immunity , vol.34 , pp. 269-280
    • Bomsel, M.1    Tudor, D.2    Drillet, A.S.3    Alfsen, A.4    Ganor, Y.5    Roger, M.G.6
  • 24
    • 36048991264 scopus 로고    scopus 로고
    • No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys
    • Letvin NL, Rao SS, Dang V, Buzby AP, Korioth-Schmitz B, Dombagoda D, et al. No evidence for consistent virus-specific immunity in simian immunodeficiency virus-exposed, uninfected rhesus monkeys. J Virol 2007; 81:12368-12374.
    • (2007) J Virol , vol.81 , pp. 12368-12374
    • Letvin, N.L.1    Rao, S.S.2    Dang, V.3    Buzby, A.P.4    Korioth-Schmitz, B.5    Dombagoda, D.6
  • 25
    • 0035134669 scopus 로고    scopus 로고
    • Late seroconversion in HIV-resistant Nairobi prostitutes despite preexisting HIV-specific CD8R responses
    • Kaul R, Rowland-Jones SL, Kimani J, Dong T, Yang HB, Kiama P, et al. Late seroconversion in HIV-resistant Nairobi prostitutes despite preexisting HIV-specific CD8R responses. J Clin Invest 2001; 107:341-349.
    • (2001) J Clin Invest , vol.107 , pp. 341-349
    • Kaul, R.1    Rowland-Jones, S.L.2    Kimani, J.3    Dong, T.4    Yang, H.B.5    Kiama, P.6
  • 26
    • 4143148495 scopus 로고    scopus 로고
    • Immunological and virological study of enfuvirtide-treated HIV-positive patients
    • Barretina J, Blanco J, Bonjoch A, Llano A, Clotet B, Esté JA. Immunological and virological study of enfuvirtide-treated HIV-positive patients. AIDS 2004; 18:1673-1682.
    • (2004) AIDS , vol.18 , pp. 1673-1682
    • Barretina, J.1    Blanco, J.2    Bonjoch, A.3    Llano, A.4    Clotet, B.5    Esté, J.A.6
  • 27
    • 4744354507 scopus 로고    scopus 로고
    • R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism
    • Blanco J, Barretina J, Clotet B, Esté JA. R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism. J Leukoc Biol 2004; 76:804-811.
    • (2004) J Leukoc Biol , vol.76 , pp. 804-811
    • Blanco, J.1    Barretina, J.2    Clotet, B.3    Esté, J.A.4
  • 28
    • 80955179554 scopus 로고    scopus 로고
    • A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity
    • Sánchez-Palomino S, Massanella M, Carrillo J, García A, García F, González N, et al. A cell-to-cell HIV transfer assay identifies humoral responses with broad neutralization activity. Vaccine 2011; 29:5250-5259.
    • (2011) Vaccine , vol.29 , pp. 5250-5259
    • Sánchez-Palomino, S.1    Massanella, M.2    Carrillo, J.3    García, A.4    García, F.5    González, N.6
  • 29
    • 0037455580 scopus 로고    scopus 로고
    • Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events
    • Blanco J, Barretina J, Ferri KF, Jacotot E, Gutiérrez A, Armand-Ugón M, et al. Cell-surface-expressed HIV-1 envelope induces the death of CD4 T cells during GP41-mediated hemifusion-like events. Virology 2003; 305:318-329.
    • (2003) Virology , vol.305 , pp. 318-329
    • Blanco, J.1    Barretina, J.2    Ferri, K.F.3    Jacotot, E.4    Gutiérrez, A.5    Armand-Ugón, M.6
  • 30
    • 3042720288 scopus 로고    scopus 로고
    • Humoral immunity in HIV-1 exposure: Cause or effect of HIV resistance?
    • Lopalco L. Humoral immunity in HIV-1 exposure: cause or effect of HIV resistance? Curr HIV Res 2004; 2:127-139.
    • (2004) Curr HIV Res , vol.2 , pp. 127-139
    • Lopalco, L.1
  • 31
    • 0040272195 scopus 로고    scopus 로고
    • Human immunodeficiency virus (HIV)-specific IgA and HIV neutralizing activity in the serum of exposed seronegative partners of HIV-seropositive persons
    • Mazzoli S, Lopalco L, Salvi A, Trabattoni D, Lo Caputo S, Semplici F, et al. Human immunodeficiency virus (HIV)-specific IgA and HIV neutralizing activity in the serum of exposed seronegative partners of HIV-seropositive persons. J Infect Dis 1999; 180:871-875.
    • (1999) J Infect Dis , vol.180 , pp. 871-875
    • Mazzoli, S.1    Lopalco, L.2    Salvi, A.3    Trabattoni, D.4    Lo Caputo, S.5    Semplici, F.6
  • 32
    • 69249086612 scopus 로고    scopus 로고
    • HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(R) cell infection: An IgA gene and functional analysis
    • Tudor D, Derrien M, Diomede L, Drillet AS, Houimel M, Moog C, et al. HIV-1 gp41-specific monoclonal mucosal IgAs derived from highly exposed but IgG-seronegative individuals block HIV-1 epithelial transcytosis and neutralize CD4(R) cell infection: an IgA gene and functional analysis. Mucosal Immunol 2009; 2:412-426.
    • (2009) Mucosal Immunol , vol.2 , pp. 412-426
    • Tudor, D.1    Derrien, M.2    Diomede, L.3    Drillet, A.S.4    Houimel, M.5    Moog, C.6
  • 33
    • 13644254926 scopus 로고    scopus 로고
    • Predictive value of anticell and antihuman immunodeficiency virus (HIV) humoral responses in HIV-1-exposed seronegative cohorts of European and Asian origin
    • Lopalco L, Barassi C, Paolucci C, Breda D, Brunelli D, Nguyen M, et al. Predictive value of anticell and antihuman immunodeficiency virus (HIV) humoral responses in HIV-1-exposed seronegative cohorts of European and Asian origin. J Gen Virol 2005; 86:339-348.
    • (2005) J Gen Virol , vol.86 , pp. 339-348
    • Lopalco, L.1    Barassi, C.2    Paolucci, C.3    Breda, D.4    Brunelli, D.5    Nguyen, M.6
  • 34
    • 23244434512 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies
    • Li M, Gao F, Mascola JR, Stamatatos L, Polonis VR, Koutsoukos M, et al. Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies. J Virol 2005; 79:10108-10125.
    • (2005) J Virol , vol.79 , pp. 10108-10125
    • Li, M.1    Gao, F.2    Mascola, J.R.3    Stamatatos, L.4    Polonis, V.R.5    Koutsoukos, M.6
  • 35
    • 0037470227 scopus 로고    scopus 로고
    • The prefusogenic intermediate of HIV-1 gp41 contains exposed C-peptide regions
    • Koshiba T, Chan DC. The prefusogenic intermediate of HIV-1 gp41 contains exposed C-peptide regions. J Biol Chem 2003; 278:7573-7579.
    • (2003) J Biol Chem , vol.278 , pp. 7573-7579
    • Koshiba, T.1    Chan, D.C.2
  • 36
    • 0031902829 scopus 로고    scopus 로고
    • CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: Consequences for virus entry and neutralization
    • Sullivan N, Sun Y, Sattentau Q, Thali M, Wu D, Denisova G, et al. CD4-Induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: consequences for virus entry and neutralization. J Virol 1998; 72:4694-4703.
    • (1998) J Virol , vol.72 , pp. 4694-4703
    • Sullivan, N.1    Sun, Y.2    Sattentau, Q.3    Thali, M.4    Wu, D.5    Denisova, G.6
  • 37
    • 77957573505 scopus 로고    scopus 로고
    • The humoral response to HIV-1: New insights, renewed focus
    • Alter G, Moody MA. The humoral response to HIV-1: new insights, renewed focus. J Infect Dis 2010; 202 (Suppl 2):S315-S322.
    • (2010) J Infect Dis , vol.202 , Issue.SUPPL. 2
    • Alter, G.1    Moody, M.A.2
  • 39
    • 33947721996 scopus 로고    scopus 로고
    • The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies
    • Zhou Z-H, Zhang Y, Hu Y-F, Wahl LM, Cisar JO, Notkins AL. The broad antibacterial activity of the natural antibody repertoire is due to polyreactive antibodies. Cell Host Microbe 2007; 1:51-61.
    • (2007) Cell Host Microbe , vol.1 , pp. 51-61
    • Zhou, Z.-H.1    Zhang, Y.2    Hu, Y.-F.3    Wahl, L.M.4    Cisar, J.O.5    Notkins, A.L.6
  • 40
    • 0027914967 scopus 로고
    • False-positive serologic tests for human T-cell lymphotropic virus type I among blood donors following influenza vaccination 1992
    • Centers for Disease Control and Prevention (CDC)
    • Centers for Disease Control and Prevention (CDC). False-positive serologic tests for human T-cell lymphotropic virus type I among blood donors following influenza vaccination, 1992. MMWR Morb Mortal Wkly Rep 1993; 42:173-175.
    • (1993) MMWR Morb Mortal Wkly Rep , vol.42 , pp. 173-175
  • 41
    • 56349094315 scopus 로고    scopus 로고
    • Systemic neutralizing antibodies induced by long interval mucosally primed systemically boosted immunization correlate with protection from mucosal SHIV challenge
    • Bogers WMJM, Davis D, Baak I, Kan E, Hofman S, Sun Y, et al. Systemic neutralizing antibodies induced by long interval mucosally primed systemically boosted immunization correlate with protection from mucosal SHIV challenge. Virology 2008; 382:217-225.
    • (2008) Virology , vol.382 , pp. 217-225
    • Bogers, W.M.J.M.1    Davis, D.2    Baak, I.3    Kan, E.4    Hofman, S.5    Sun, Y.6
  • 42
    • 35348894949 scopus 로고    scopus 로고
    • Immunological profile of heterosexual highly HIVexposed uninfected individuals: Predominant role of CD4 and CD8 T-cell activation
    • Suy A, Castro P, Nomdedeu M, García F, López A, Fumero E, et al. Immunological profile of heterosexual highly HIVexposed uninfected individuals: predominant role of CD4 and CD8 T-cell activation. J Infect Dis 2007; 196:1191-1201.
    • (2007) J Infect Dis , vol.196 , pp. 1191-1201
    • Suy, A.1    Castro, P.2    Nomdedeu, M.3    García, F.4    López, A.5    Fumero, E.6
  • 43
    • 84868159913 scopus 로고    scopus 로고
    • Antibody-mediated Fc(receptor-based mechanisms of HIV inhibition: Recent findings and new vaccination strategies
    • Holl V, Peressin M, Moog C. Antibody-mediated Fc(receptor-based mechanisms of HIV inhibition: recent findings and new vaccination strategies. Viruses 2009; 1:1265-1294.
    • (2009) Viruses , vol.1 , pp. 1265-1294
    • Holl, V.1    Peressin, M.2    Moog, C.3
  • 44
    • 77951080820 scopus 로고    scopus 로고
    • Antiphospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines
    • Moody MA, Liao H-X, Alam SM, Scearce RM, Plonk MK, Kozink DM, et al. Antiphospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines. J Exp Med 2010; 207:763-776.
    • (2010) J Exp Med , vol.207 , pp. 763-776
    • Moody, M.A.1    Liao, H.-X.2    Alam, S.M.3    Scearce, R.M.4    Plonk, M.K.5    Kozink, D.M.6
  • 45
    • 79953804550 scopus 로고    scopus 로고
    • Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN)
    • Tomescu C, Abdulhaqq S, Montaner LJ. Evidence for the innate immune response as a correlate of protection in human immunodeficiency virus (HIV)-1 highly exposed seronegative subjects (HESN). Clin Exp Immunol 2011; 164:158-169.
    • (2011) Clin Exp Immunol , vol.164 , pp. 158-169
    • Tomescu, C.1    Abdulhaqq, S.2    Montaner, L.J.3
  • 46
    • 80055118908 scopus 로고    scopus 로고
    • Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated
    • Liao H-X, Chen X, Munshaw S, Zhang R, Marshall DJ, Vandergrift N, et al. Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. J Exp Med 2011; 208:2237-2249. Investigación en SIDA SIDA
    • (2011) J Exp Med , vol.208 , pp. 2237-2249
    • Liao, H.-X.1    Chen, X.2    Munshaw, S.3    Zhang, R.4    Marshall, D.J.5    Vandergrift, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.