Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells

Cancer Research

Volumn 73, Issue 12, 2013, Pages 3671-3682

  Arias Romero, Luis E ^a   Villamar Cruz, Olga ^a   Huang, Min ^a   Hoeflich, Klaus P ^b   Chernoff, Jonathan ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ICRT 14; ICRT 3; JW 55; P21 ACTIVATED KINASE 1; P21 ACTIVATED KINASE 2; PF 3758309; PROTEIN INHIBITOR; PROTEIN SERINE THREONINE KINASE INHIBITOR; TRASTUZUMAB; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; BREAST EPITHELIUM; CANCER CELL CULTURE; CANCER REGRESSION; CONTROLLED STUDY; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME DEFICIENCY; ENZYME PHOSPHORYLATION; EPITHELIUM CELL; FEMALE; GENE SILENCING; GENE TARGETING; IC 50; IMMUNOHISTOCHEMISTRY; MALIGNANT TRANSFORMATION; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; SURVIVAL TIME; TRANSGENIC MOUSE; TUMOR XENOGRAFT;

ANIMALS; APOPTOSIS; BETA CATENIN; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; HUMANS; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; MICE, SCID; MICE, TRANSGENIC; P21-ACTIVATED KINASES; PYRAZOLES; PYRROLES; RECEPTOR, ERBB-2; RNA INTERFERENCE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84879101353     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-12-4453     Document Type: Article

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