IgG2 Fc structure and the dynamic features of the IgG CH2-CH3 interface

Molecular Immunology

Volumn 56, Issue 1-2, 2013, Pages 131-139

  Teplyakov, Alexey ^a   Zhao, Yonghong ^a   Malia, Thomas J ^a   Obmolova, Galina ^a   Gilliland, Gary L ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

Author keywords

Fc effector function; Fc R interactions; IgG CH2 CH3 Fc interface; Immunoglobulin Fc; X ray structure

Indexed keywords

ALANINE; AMINO ACID; FC RECEPTOR; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G4;

ARTICLE; CRYSTALLIZATION; HUMAN; HUMAN CELL; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; STATIC ELECTRICITY; WATER STRUCTURE;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HEK293 CELLS; HUMANS; HYDROGEN BONDING; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, IGG; SEQUENCE HOMOLOGY, AMINO ACID; STATIC ELECTRICITY;

EID: 84879088841     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2013.03.018     Document Type: Article

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