Recombinant human erythropoietin attenuates neuronal apoptosis and cognitive defects via JAK2/STAT3 signaling in experimental endotoxemia

Journal of Surgical Research

Volumn 183, Issue 1, 2013, Pages 304-312

  Zhou, Ting Fa ^a   Yu, Jin Gui ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Apoptosis; Cecal ligation and peroration; Hippocampus; JAK2 STAT3; Learning and memory; Neuronal cultures; rhEPO; Sepsis

Indexed keywords

JANUS KINASE 2; LACTATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; PROTEIN BAX; PROTEIN BCL XL; RECOMBINANT ERYTHROPOIETIN; SHORT HAIRPIN RNA; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL ASSAY; CELL COUNT; CELL VIABILITY; COGNITIVE DEFECT; CONTROLLED STUDY; EMBRYO; ENDOTOXEMIA; ENZYME INHIBITION; ENZYME RELEASE; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; LEARNING DISORDER; MALE; MAZE TEST; MEMORY DISORDER; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SEPSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BCL-X PROTEIN; BRAIN DISEASES; CECUM; CELL SURVIVAL; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; ENDOTOXEMIA; ERYTHROPOIETIN; HUMANS; JANUS KINASE 2; LEARNING DISORDERS; LIGATION; LIPOPOLYSACCHARIDES; MALE; MEMORY DISORDERS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; STAT3 TRANSCRIPTION FACTOR;

EID: 84879075904     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2012.11.035     Document Type: Article

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