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Volumn 131, Issue 6, 2013, Pages 766-776

Transcription, translation, and function of lubricin, a boundary lubricant, at the ocular surface

Author keywords

[No Author keywords available]

Indexed keywords

BOVINE SERUM ALBUMIN; FLUORESCEIN; GLYCOPROTEIN; HYALURONIC ACID; LUBRICIN; MESSENGER RNA; PROTEOGLYCAN; PROTEOGLYCAN 4; UNCLASSIFIED DRUG;

EID: 84879054388     PISSN: 21686165     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaophthalmol.2013.2385     Document Type: Article
Times cited : (104)

References (63)
  • 1
    • 33947143505 scopus 로고    scopus 로고
    • Boundary lubrication of articular cartilage: Role of synovial fluid constituents
    • DOI 10.1002/art.22446
    • Schmidt TA, Gastelum NS, Nguyen QT, Schumacher BL, Sah RL. Boundary lubrication of articular cartilage: role of synovial fluid constituents. Arthritis Rheum. 2007;56(3):882-891. (Pubitemid 46399436)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.3 , pp. 882-891
    • Schmidt, T.A.1    Gastelum, N.S.2    Nguyen, Q.T.3    Schumacher, B.L.4    Sah, R.L.5
  • 3
    • 4544256289 scopus 로고    scopus 로고
    • Lubricin and surfacing of articular joints
    • Jay DJ. Lubricin and surfacing of articular joints. Curr Opin Orthop. 2004;15(5):355-359.
    • (2004) Curr Opin Orthop , vol.15 , Issue.5 , pp. 355-359
    • Jay, D.J.1
  • 4
    • 80052506675 scopus 로고    scopus 로고
    • Lubricin: A novel potential biotherapeutic approaches for the treatment of osteoarthritis
    • Bao JP, Chen WP, Wu LD. Lubricin: a novel potential biotherapeutic approaches for the treatment of osteoarthritis. Mol Biol Rep. 2011;38(5):2879-2885.
    • (2011) Mol Biol Rep , vol.38 , Issue.5 , pp. 2879-2885
    • Bao, J.P.1    Chen, W.P.2    Wu, L.D.3
  • 5
    • 4444345144 scopus 로고    scopus 로고
    • Synthesis of proteoglycan 4 by chondrocyte subpopulations in cartilage explants, monolayer cultures, and resurfaced cartilage cultures
    • DOI 10.1002/art.20480
    • Schmidt TA, Schumacher BL, Klein TJ, Voegtline MS, Sah RL. Synthesis of proteoglycan 4 by chondrocyte subpopulations in cartilage explants, monolayer cultures, and resurfaced cartilage cultures. Arthritis Rheum . 2004;50(9):2849-2857. (Pubitemid 39209522)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.9 , pp. 2849-2857
    • Schmidt, T.A.1    Schumacher, B.L.2    Klein, T.J.3    Voegtline, M.S.4    Sah, R.L.5
  • 8
    • 33846208701 scopus 로고    scopus 로고
    • Reduced expression and proteolytic susceptibility of lubricin/superficial zone protein may explain early elevation in the coefficient of friction in the joints of rats with antigen-induced arthritis
    • Elsaid KA, Jay GD, Chichester CO. Reduced expression and proteolytic susceptibility of lubricin/superficial zone protein may explain early elevation in the coefficient of friction in the joints of rats with antigen-induced arthritis. Arthritis Rheum. 2007;56(1):108-116.
    • (2007) Arthritis Rheum , vol.56 , Issue.1 , pp. 108-116
    • Elsaid, K.A.1    Jay, G.D.2    Chichester, C.O.3
  • 9
    • 78751557802 scopus 로고    scopus 로고
    • Effects of supplemental intra-articular lubricin and hyaluronic acid on the progression of posttraumatic arthritis in the anterior cruciate ligament-deficient rat knee
    • Teeple E, Elsaid KA, Jay GD, et al. Effects of supplemental intra-articular lubricin and hyaluronic acid on the progression of posttraumatic arthritis in the anterior cruciate ligament-deficient rat knee. Am J Sports Med. 2011;39(1):164-172.
    • (2011) Am J Sports Med , vol.39 , Issue.1 , pp. 164-172
    • Teeple, E.1    Elsaid, K.A.2    Jay, G.D.3
  • 10
    • 84861002642 scopus 로고    scopus 로고
    • Prevention of cartilage degeneration and gait asymmetry by lubricin tribosupplementation in the rat following anterior cruciate ligament transection
    • Jay GD, Elsaid KA, Kelly KA, et al. Prevention of cartilage degeneration and gait asymmetry by lubricin tribosupplementation in the rat following anterior cruciate ligament transection. Arthritis Rheum. 2012;64(4):1162-1171.
    • (2012) Arthritis Rheum , vol.64 , Issue.4 , pp. 1162-1171
    • Jay, G.D.1    Elsaid, K.A.2    Kelly, K.A.3
  • 11
    • 61649118485 scopus 로고    scopus 로고
    • Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin
    • Flannery CR, Zollner R, Corcoran C, et al. Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin. Arthritis Rheum. 2009;60(3):840-847.
    • (2009) Arthritis Rheum , vol.60 , Issue.3 , pp. 840-847
    • Flannery, C.R.1    Zollner, R.2    Corcoran, C.3
  • 12
    • 77951035922 scopus 로고    scopus 로고
    • Novel therapies in OA
    • Flannery CR. Novel therapies in OA. Curr Drug Targets. 2010;11(5):614-619.
    • (2010) Curr Drug Targets , vol.11 , Issue.5 , pp. 614-619
    • Flannery, C.R.1
  • 13
    • 34347257439 scopus 로고    scopus 로고
    • The epidemiology of dry eye disease: Report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007)
    • The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf. 2007;5(2):93-107.
    • (2007) Ocul Surf , vol.5 , Issue.2 , pp. 93-107
  • 15
    • 66949164787 scopus 로고    scopus 로고
    • Prevalence of dry eye disease among US men: Estimates from the Physicians' Health Studies
    • Schaumberg DA, Dana R, Buring JE, Sullivan DA. Prevalence of dry eye disease among US men: estimates from the Physicians' Health Studies. Arch Ophthalmol. 2009;127(6):763-768.
    • (2009) Arch Ophthalmol , vol.127 , Issue.6 , pp. 763-768
    • Schaumberg, D.A.1    Dana, R.2    Buring, J.E.3    Sullivan, D.A.4
  • 16
    • 33745014599 scopus 로고    scopus 로고
    • Comparative effects of estrogen on matrix metalloproteinases and cytokines in immortalized and primary human corneal epithelial cell cultures
    • DOI 10.1097/01.ico.0000220777.70981.46, PII 0000322620060500000015
    • Suzuki T, Sullivan DA. Comparative effects of estrogen on matrix metalloproteinases and cytokines in immortalized and primary human corneal epithelial cell cultures. Cornea. 2006;25(4):454-459. (Pubitemid 44620132)
    • (2006) Cornea , vol.25 , Issue.4 , pp. 454-459
    • Suzuki, T.1    Sullivan, D.A.2
  • 19
    • 77955857267 scopus 로고    scopus 로고
    • Culture, immortalization, and characterization of human meibomian gland epithelial cells
    • Liu S, Hatton MP, Khandelwal P, Sullivan DA. Culture, immortalization, and characterization of human meibomian gland epithelial cells. Invest Ophthalmol Vis Sci. 2010;51(8):3993-4005.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.8 , pp. 3993-4005
    • Liu, S.1    Hatton, M.P.2    Khandelwal, P.3    Sullivan, D.A.4
  • 20
    • 0034528946 scopus 로고    scopus 로고
    • Isolation, characterization and mapping of the mouse and human PRG4 (proteoglycan 4) genes
    • Ikegawa S, Sano M, Koshizuka Y, Nakamura Y. Isolation, characterization and mapping of the mouse and human PRG4 (proteoglycan 4) genes. Cytogenet Cell Genet. 2000;90(3-4):291-297. (Pubitemid 32008781)
    • (2000) Cytogenetics and Cell Genetics , vol.90 , Issue.3-4 , pp. 291-297
    • Ikegawa, S.1    Sano, M.2    Koshizuka, Y.3    Nakamura, Y.4
  • 21
    • 0034060151 scopus 로고    scopus 로고
    • Conjunctiva-associated lymphoid tissue in the human eye
    • Knop N, Knop E. Conjunctiva-associated lymphoid tissue in the human eye. Invest Ophthalmol Vis Sci. 2000;41(6):1270-1279. (Pubitemid 30261847)
    • (2000) Investigative Ophthalmology and Visual Science , vol.41 , Issue.6 , pp. 1270-1279
    • Knop, N.1    Knop, E.2
  • 22
    • 67349220668 scopus 로고    scopus 로고
    • Disulfide-bonded multimers of proteoglycan 4 PRG4 are present in normal synovial fluids
    • Schmidt TA, Plaas AH, Sandy JD. Disulfide-bonded multimers of proteoglycan 4 PRG4 are present in normal synovial fluids. Biochim Biophys Acta. 2009; 1790(5):375-384.
    • (2009) Biochim Biophys Acta , vol.1790 , Issue.5 , pp. 375-384
    • Schmidt, T.A.1    Plaas, A.H.2    Sandy, J.D.3
  • 24
    • 84873200675 scopus 로고    scopus 로고
    • Molecular weight characterization of PRG4 proteins using multi-angle laser light scattering (MALLS)
    • Steele BL, Alvarez-Veronesi MC, Schmidt TA. Molecular weight characterization of PRG4 proteins using multi-angle laser light scattering (MALLS). Osteoarthritis Cartilage. 2013;21(3):498-504.
    • (2013) Osteoarthritis Cartilage , vol.21 , Issue.3 , pp. 498-504
    • Steele, B.L.1    Alvarez-Veronesi, M.C.2    Schmidt, T.A.3
  • 26
    • 84855343992 scopus 로고    scopus 로고
    • Dosedependent and synergistic effects of proteoglycan 4 on boundary lubrication at a human cornea-polydimethylsiloxane biointerface
    • Morrison S, Sullivan DA, Sullivan BD, Sheardown H, Schmidt TA. Dosedependent and synergistic effects of proteoglycan 4 on boundary lubrication at a human cornea-polydimethylsiloxane biointerface. Eye Contact Lens . 2012;38(1):27-35.
    • (2012) Eye Contact Lens , vol.38 , Issue.1 , pp. 27-35
    • Morrison, S.1    Sullivan, D.A.2    Sullivan, B.D.3    Sheardown, H.4    Schmidt, T.A.5
  • 28
    • 0002854323 scopus 로고
    • The precorneal film: Biomicroscopical, histological and clinical investigations
    • Ehlers N. The precorneal film: biomicroscopical, histological and clinical investigations. Acta Ophthalmol Suppl. 1965;81:109-113.
    • (1965) Acta Ophthalmol Suppl , vol.81 , pp. 109-113
    • Ehlers, N.1
  • 29
    • 79952755951 scopus 로고    scopus 로고
    • The lid wiper and muco-cutaneous junction anatomy of the human eyelid margins: An in vivo confocal and histological study
    • Knop E, Knop N, Zhivov A, et al. The lid wiper and muco-cutaneous junction anatomy of the human eyelid margins: an in vivo confocal and histological study. J Anat. 2011;218(4):449-461.
    • (2011) J Anat , vol.218 , Issue.4 , pp. 449-461
    • Knop, E.1    Knop, N.2    Zhivov, A.3
  • 30
    • 0026437995 scopus 로고
    • Characterization of a bovine synovial fluid lubricating factor, II: Comparison with purified ocular and salivary mucin
    • Jay GD, Hong BS. Characterization of a bovine synovial fluid lubricating factor, II: comparison with purified ocular and salivary mucin. Connect Tissue Res. 1992;28(1-2):89-98.
    • (1992) Connect Tissue Res , vol.28 , Issue.1-2 , pp. 89-98
    • Jay, G.D.1    Hong, B.S.2
  • 31
    • 84861094089 scopus 로고    scopus 로고
    • The lid wiper contains goblet cells and goblet cell crypts for ocular surface lubrication during the blink
    • Knop N, Korb DR, Blackie CA, Knop E. The lid wiper contains goblet cells and goblet cell crypts for ocular surface lubrication during the blink. Cornea. 2012;31(6):668-679.
    • (2012) Cornea , vol.31 , Issue.6 , pp. 668-679
    • Knop, N.1    Korb, D.R.2    Blackie, C.A.3    Knop, E.4
  • 33
    • 46149122562 scopus 로고    scopus 로고
    • A new look at lubrication of the ocular surface: Fluid mechanics behind the blinking eyelids
    • Cher I. A new look at lubrication of the ocular surface: fluid mechanics behind the blinking eyelids. Ocul Surf. 2008;6(2):79-86. (Pubitemid 351902626)
    • (2008) Ocular Surface , vol.6 , Issue.2 , pp. 79-86
    • Cher, I.1
  • 34
    • 34347256116 scopus 로고    scopus 로고
    • Methodologies to diagnose and monitor dry eye disease: Report of the Diagnostic Methodology Subcommittee of the International Dry Eye WorkShop (2007)
    • Methodologies to diagnose and monitor dry eye disease: report of the Diagnostic Methodology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf. 2007;5(2):108-152.
    • (2007) Ocul Surf , vol.5 , Issue.2 , pp. 108-152
  • 36
    • 34347243555 scopus 로고    scopus 로고
    • The definition and classification of dry eye disease: Report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007)
    • The definition and classification of dry eye disease: report of the Definition and Classification Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf. 2007;5(2):75-92.
    • (2007) Ocul Surf , vol.5 , Issue.2 , pp. 75-92
  • 37
    • 85027932161 scopus 로고    scopus 로고
    • Report of the TFOS/ARVO Symposium on global treatments for dry eye disease: An unmet need
    • Sullivan DA, Hammitt KM, Schaumberg DA, et al. Report of the TFOS/ARVO Symposium on global treatments for dry eye disease: an unmet need. Ocul Surf. 2012;10(2):108-116.
    • (2012) Ocul Surf , vol.10 , Issue.2 , pp. 108-116
    • Sullivan, D.A.1    Hammitt, K.M.2    Schaumberg, D.A.3
  • 40
    • 20744452194 scopus 로고    scopus 로고
    • Association of articular cartilage degradation and loss of boundary-lubricating ability of synovial fluid following injury and inflammatory arthritis
    • DOI 10.1002/art.21038
    • Elsaid KA, Jay GD, Warman ML, Rhee DK, Chichester CO. Association of articular cartilage degradation and loss of boundary-lubricating ability of synovial fluid following injury and inflammatory arthritis. Arthritis Rheum. 2005;52(6):1746-1755. (Pubitemid 40852883)
    • (2005) Arthritis and Rheumatism , vol.52 , Issue.6 , pp. 1746-1755
    • Elsaid, K.A.1    Jay, G.D.2    Warman, M.L.3    Rhee, D.K.4    Chichester, C.O.5
  • 41
    • 84859450349 scopus 로고    scopus 로고
    • Regulation of lubricin expression and metabolism in synovial joints
    • Jones ARC, Keohan C, Sheldon R, et al. Regulation of lubricin expression and metabolism in synovial joints. Eur Cell Mater. 2006;12(suppl 1):17.
    • (2006) Eur Cell Mater , vol.12 , Issue.SUPPL. 1 , pp. 17
    • Jones, A.R.C.1    Keohan, C.2    Sheldon, R.3
  • 42
    • 52049101630 scopus 로고    scopus 로고
    • Induction of chondrogenesis and expression of superficial zone protein (SZP)/lubricin by mesenchymal progenitors in the infrapatellar fat pad of the knee joint treated with TGF-beta1 and BMP-7
    • Lee SY, Nakagawa T, Reddi AH. Induction of chondrogenesis and expression of superficial zone protein (SZP)/lubricin by mesenchymal progenitors in the infrapatellar fat pad of the knee joint treated with TGF-beta1 and BMP-7. Biochem Biophys Res Commun. 2008;376(1):148-153.
    • (2008) Biochem Biophys Res Commun , vol.376 , Issue.1 , pp. 148-153
    • Lee, S.Y.1    Nakagawa, T.2    Reddi, A.H.3
  • 45
    • 33749142312 scopus 로고    scopus 로고
    • Mapping lubricin in canine musculoskeletal tissues
    • DOI 10.1080/03008200600846754, PII K0813NP3J045M868
    • Sun Y, Berger EJ, Zhao C, An KN, Amadio PC, Jay G. Mapping lubricin in canine musculoskeletal tissues. Connect Tissue Res. 2006;47(4):215-221. (Pubitemid 44467653)
    • (2006) Connective Tissue Research , vol.47 , Issue.4 , pp. 215-221
    • Sun, Y.1    Berger, E.J.2    Zhao, C.3    An, K.-N.4    Amadio, P.C.5    Jay, G.6
  • 46
    • 0033608160 scopus 로고    scopus 로고
    • Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism
    • DOI 10.1006/bbrc.1998.0104
    • Flannery CR, Hughes CE, Schumacher BL, et al. Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism. Biochem Biophys Res Commun. 1999;254(3):535-541. (Pubitemid 29290501)
    • (1999) Biochemical and Biophysical Research Communications , vol.254 , Issue.3 , pp. 535-541
    • Flannery, C.R.1    Hughes, C.E.2    Schumacher, B.L.3    Tudor, D.4    Aydelotte, M.B.5    Kuettner, K.E.6    Caterson, B.7
  • 47
    • 80055024618 scopus 로고    scopus 로고
    • Proteoglycan 4, a novel immunomodulatory factor, regulates parathyroid hormone actions on hematopoietic cells
    • Novince CM, Koh AJ, Michalski MN, et al. Proteoglycan 4, a novel immunomodulatory factor, regulates parathyroid hormone actions on hematopoietic cells. Am J Pathol. 2011;179(5):2431-2442.
    • (2011) Am J Pathol , vol.179 , Issue.5 , pp. 2431-2442
    • Novince, C.M.1    Koh, A.J.2    Michalski, M.N.3
  • 48
    • 0022000548 scopus 로고
    • The molecular structure and lubricating activity of lubricin isolated from bovine and human synovial fluids
    • Swann DA, Silver FH, Slayter HS, Stafford W, Shore E. The molecular structure and lubricating activity of lubricin isolated from bovine and human synovial fluids. Biochem J. 1985;225(1):195-201. (Pubitemid 15151970)
    • (1985) Biochemical Journal , vol.225 , Issue.1 , pp. 195-201
    • Swann, D.A.1    Silver, F.H.2    Slayter, H.S.3
  • 50
    • 0029400147 scopus 로고
    • Lubrication of human and bovine enamel compared in an artificial mouth
    • Reeh ES, Douglas WH, Levine MJ. Lubrication of human and bovine enamel compared in an artificial mouth. Arch Oral Biol. 1995;40(11):1063-1072.
    • (1995) Arch Oral Biol , vol.40 , Issue.11 , pp. 1063-1072
    • Reeh, E.S.1    Douglas, W.H.2    Levine, M.J.3
  • 51
    • 0030160244 scopus 로고    scopus 로고
    • Lubrication of saliva substitutes at enamel-to-enamel contacts in an artificial mouth
    • Reeh ES, Douglas WH, Levine MJ. Lubrication of saliva substitutes at enamel-toenamel contacts in an artificial mouth. J Prosthet Dent. 1996;75(6):649-656. (Pubitemid 126653678)
    • (1996) Journal of Prosthetic Dentistry , vol.75 , Issue.6 , pp. 649-656
    • Reeh, E.S.1    Douglas, W.H.2    Levine, M.J.3
  • 52
    • 78649638780 scopus 로고    scopus 로고
    • Enzymatic depletion of tumor hyaluronan induces antitumor responses in preclinical animal models
    • Thompson CB, Shepard HM, O'Connor PM, et al. Enzymatic depletion of tumor hyaluronan induces antitumor responses in preclinical animal models. Mol Cancer Ther. 2010;9(11):3052-3064.
    • (2010) Mol Cancer Ther , vol.9 , Issue.11 , pp. 3052-3064
    • Thompson, C.B.1    Shepard, H.M.2    O'Connor, P.M.3
  • 53
    • 77953760549 scopus 로고    scopus 로고
    • Stromal hyaluronan interaction with epithelial CD44 variants promotes prostate cancer invasiveness by augmenting expression and function of hepatocyte growth factor and androgen receptor
    • Ghatak S, Hascall VC, Markwald RR, Misra S. Stromal hyaluronan interaction with epithelial CD44 variants promotes prostate cancer invasiveness by augmenting expression and function of hepatocyte growth factor and androgen receptor. J Biol Chem. 2010;285(26):19821-19832.
    • (2010) J Biol Chem , vol.285 , Issue.26 , pp. 19821-19832
    • Ghatak, S.1    Hascall, V.C.2    Markwald, R.R.3    Misra, S.4
  • 54
    • 79960673142 scopus 로고    scopus 로고
    • Treatment of acute iatrogenic cystitis secondary to bladder chemo-immuno-instillation or pelvic radiotherapy
    • in Italian
    • Sommariva ML, Sandri SD, Guerrer CS. Treatment of acute iatrogenic cystitis secondary to bladder chemo-immuno-instillation or pelvic radiotherapy [in Italian]. Urologia. 2010;77(3):187-192.
    • (2010) Urologia , vol.77 , Issue.3 , pp. 187-192
    • Sommariva, M.L.1    Sandri, S.D.2    Guerrer, C.S.3
  • 56
    • 79952325542 scopus 로고    scopus 로고
    • The effect of hyaluronic acid (Cicatridine) on healing and regeneration of the uterine cervix and vagina and vulvar dystrophy therapy
    • Markowska J, Madry R, Markowska A. The effect of hyaluronic acid (Cicatridine) on healing and regeneration of the uterine cervix and vagina and vulvar dystrophy therapy. Eur J Gynaecol Oncol. 2011;32(1):65-68.
    • (2011) Eur J Gynaecol Oncol , vol.32 , Issue.1 , pp. 65-68
    • Markowska, J.1    Madry, R.2    Markowska, A.3
  • 57
    • 78049297871 scopus 로고    scopus 로고
    • Intracervical application of hyaluronan improves cervical relaxation in the ewe
    • Perry K, HaresignW,Wathes DC, Khalid M. Intracervical application of hyaluronan improves cervical relaxation in the ewe. Theriogenology. 2010;74(9):1685-1690.
    • (2010) Theriogenology , vol.74 , Issue.9 , pp. 1685-1690
    • Perry, K.1    Haresign, W.2    Wathes, D.C.3    Khalid, M.4
  • 58
    • 77952110844 scopus 로고    scopus 로고
    • Hyaluronic acid reagent suppressed endometriotic lesion formation in a mouse model
    • Hasegawa A, Yoshino O, Osuga Y, et al. Hyaluronic acid reagent suppressed endometriotic lesion formation in a mouse model. Fertil Steril. 2010;93(8):2757-2759.
    • (2010) Fertil Steril , vol.93 , Issue.8 , pp. 2757-2759
    • Hasegawa, A.1    Yoshino, O.2    Osuga, Y.3
  • 59
    • 57849094463 scopus 로고    scopus 로고
    • Murine abortion is associated with enhanced hyaluronan expression and abnormal localization at the fetomaternal interface
    • Cordo-Russo R, Garcia MG, Barrientos G, et al. Murine abortion is associated with enhanced hyaluronan expression and abnormal localization at the fetomaternal interface. Placenta. 2009;30(1):88-95.
    • (2009) Placenta , vol.30 , Issue.1 , pp. 88-95
    • Cordo-Russo, R.1    Garcia, M.G.2    Barrientos, G.3
  • 60
    • 79959984703 scopus 로고    scopus 로고
    • Stimulation of TLRs by LMW-HA induces self-defense mechanisms in vaginal epithelium
    • Dusio GF, Cardani D, Zanobbio L, et al. Stimulation of TLRs by LMW-HA induces self-defense mechanisms in vaginal epithelium. Immunol Cell Biol. 2011;89(5):630-639.
    • (2011) Immunol Cell Biol , vol.89 , Issue.5 , pp. 630-639
    • Dusio, G.F.1    Cardani, D.2    Zanobbio, L.3
  • 61
    • 58249125494 scopus 로고    scopus 로고
    • Effectiveness and safety of vaginal suppositories for the treatment of the vaginal atrophy in postmenopausal women: An open, noncontrolled clinical trial
    • Costantino D, Guaraldi C. Effectiveness and safety of vaginal suppositories for the treatment of the vaginal atrophy in postmenopausal women: an open, noncontrolled clinical trial. Eur Rev Med Pharmacol Sci . 2008;12(6):411-416.
    • (2008) Eur Rev Med Pharmacol Sci , vol.12 , Issue.6 , pp. 411-416
    • Costantino, D.1    Guaraldi, C.2
  • 62
    • 78651429275 scopus 로고    scopus 로고
    • Cross-linked hyaluronan gel improves the quality of life of prostate cancer patients undergoing radiotherapy
    • Wilder RB, Barme GA, Gilbert RF, et al. Cross-linked hyaluronan gel improves the quality of life of prostate cancer patients undergoing radiotherapy. Brachytherapy. 2011;10(1):44-50.
    • (2011) Brachytherapy , vol.10 , Issue.1 , pp. 44-50
    • Wilder, R.B.1    Barme, G.A.2    Gilbert, R.F.3
  • 63
    • 80054847103 scopus 로고    scopus 로고
    • The role of sodium hyaluronate and sodium chondroitin sulphate in the management of bladder disease
    • Damiano R, Cicione A. The role of sodium hyaluronate and sodium chondroitin sulphate in the management of bladder disease. Ther Adv Urol. 2011;3(5):223-232.
    • (2011) Ther Adv Urol , vol.3 , Issue.5 , pp. 223-232
    • Damiano, R.1    Cicione, A.2


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