Stimulation of TLRs by LMW-HA induces self-defense mechanisms in vaginal epithelium

Immunology and Cell Biology

Volumn 89, Issue 5, 2011, Pages 630-639

  Dusio, Giuseppina F ^a   Cardani, Diego ^a   Zanobbio, Laura ^a   Mantovani, Martina ^a   Luchini, Patrizia ^a   Battini, Lorenzo ^a   Galli, Valentina ^a   Diana, Angela ^a   Balsari, Andrea ^a,b   Rumio, Cristiano ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

antimicrobial peptides; low molecular weight hyaluronic acid; Toll like receptors; vaginal epithelial cells; wound healing

Indexed keywords

BETA ACTIN; BETA DEFENSIN 1; BETA DEFENSIN 2; BETA DEFENSIN 3; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; HERMES ANTIGEN; HYALURONIC ACID DERIVATIVE; LACTOFERRIN; LOW MOLECULAR WEIGHT HYALURONIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; EPIDERMIS; EPITHELIUM CELL; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INNATE IMMUNITY; PROTEIN EXPRESSION; PROTEIN SECRETION; SELF DEFENSE; VAGINA EPITHELIUM; WOUND HEALING;

ADJUVANTS, IMMUNOLOGIC; BETA-DEFENSINS; CELL LINE, TRANSFORMED; EPITHELIAL CELLS; EPITHELIUM; FEMALE; GENE EXPRESSION REGULATION, ARCHAEAL; HUMANS; HYALURONIC ACID; IMMUNITY, INNATE; IMMUNOLOGIC FACTORS; INFLAMMATION MEDIATORS; LIGANDS; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4; VAGINA; WOUND HEALING;

EID: 79959984703     PISSN: 08189641     EISSN: 14401711     Source Type: Journal    
DOI: 10.1038/icb.2010.140     Document Type: Article

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