Sodium tanshinone IIA silate inhibits oxygen-glucose deprivation/recovery- induced cardiomyocyte apoptosis via suppression of the NF-κB/TNF-α pathway

British Journal of Pharmacology

Volumn 169, Issue 5, 2013, Pages 1058-1071

  Wu, Wen Yu ^a,c   Wang, Wen Yi ^a,c   Ma, Yan Ling ^a,c   Yan, Hong ^a,c   Wang, Xin Bo ^a,c   Qin, Yin Lin ^b   Su, Mei ^b   Chen, Tao ^b   Wang, Yi Ping ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^b Nanjing Carefree Medical Technology Co Ltd   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

myocardial cell apoptosis; NF B TNF ; PI3K Akt; sodium tanshinone IIA silate

Indexed keywords

CASPASE 3; CASPASE 8; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; SODIUM TANSHINONE IIA SILATE; STRESS ACTIVATED PROTEIN KINASE; TANSHINONE IIA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ABIETANE DERIVATIVE; BAX PROTEIN, RAT; CASP3 PROTEIN, RAT; CASP8 PROTEIN, RAT; GLUCOSE; OXYGEN; TANSHINONE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HEART PROTECTION; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; DRUG EFFECTS; HEART MUSCLE CELL; METABOLISM; REPERFUSION INJURY;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASE 3; CASPASE 8; CELL LINE; CELL SURVIVAL; CYTOPROTECTION; DITERPENES, ABIETANE; GLUCOSE; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; MYOCARDIAL REPERFUSION INJURY; MYOCYTES, CARDIAC; NF-KAPPA B; OXYGEN; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84879011557     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12185     Document Type: Article

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