Mechanisms of the statins cytotoxicity in freshly isolated rat hepatocytes

Journal of Biochemical and Molecular Toxicology

Volumn 27, Issue 6, 2013, Pages 287-294

  Abdoli, Narges ^a,b,c   Heidari, Reza ^b,c   Azarmi, Yadollah ^b,c   Eghbal, Mohammad Ali ^b,c  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Gutathione; Hepatotoxicity; Mitochondrial Membrane Potential; Oxidative Stress; ROS Formation; Statins

Indexed keywords

ATORVASTATIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPID; MEVINOLIN; REACTIVE OXYGEN METABOLITE; SIMVASTATIN;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CONTROLLED STUDY; DRUG CYTOTOXICITY; LIPID PEROXIDATION; LIVER CELL; LIVER MITOCHONDRION; LIVER TOXICITY; MALE; MITOCHONDRIAL DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; RAT;

ANIMALS; CELL DEATH; CELL SURVIVAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; HEPATOCYTES; HEPTANOIC ACIDS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LIPID PEROXIDATION; LOVASTATIN; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; PYRROLES; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIMVASTATIN;

RATTUS;

EID: 84879007318     PISSN: 10956670     EISSN: 10990461     Source Type: Journal    
DOI: 10.1002/jbt.21485     Document Type: Article

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