Mechanism of sulfite cytotoxicity in isolated rat hepatocytes

Chemico-Biological Interactions

Volumn 174, Issue 3, 2008, Pages 147-154

  Niknahad, Hossein ^a   O'Brien, Peter J ^b  

^a SHIRAZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cyanide; Cytotoxicity; Free radical; Hepatocytes; Molecular mechanism; Sulfite; Sulfite oxidase

Indexed keywords

BISULFITE; CYANIDE; CYTOCHROME A; CYTOCHROME C OXIDASE; CYTOCHROME P450 INHIBITOR; DEFEROXAMINE; DITHIOTHREITOL; FREE RADICAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; MALONALDEHYDE; METYRAPONE; MITOCHONDRIAL ENZYME; MOLYBDENUM; PIPERONYL BUTOXIDE; REACTIVE OXYGEN METABOLITE; SULFATE; SULFITE; SULFITE OXIDASE; TUNGSTEN;

AIR POLLUTANT; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL DEATH; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DIETARY INTAKE; DISULFIDE BOND; ENZYME INACTIVATION; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID PEROXIDATION; LIVER CELL; MALE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PH; RAT;

ANIMALS; ANTIOXIDANTS; CELL SURVIVAL; DITHIOTHREITOL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; ELECTRON TRANSPORT COMPLEX IV; ENZYME INHIBITORS; GLUTATHIONE; HEPATOCYTES; LIPID PEROXIDATION; MALE; OXYGEN CONSUMPTION; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SULFITE OXIDASE; SULFITES;

RATTUS;

EID: 48849083414     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cbi.2008.05.032     Document Type: Article

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