Synthesis and properties of thymidines with six-membered amide bridge

Bioorganic and Medicinal Chemistry

Volumn 21, Issue 14, 2013, Pages 4405-4412

  Hari, Yoshiyuki ^a   Osawa, Takashi ^a   Kotobuki, Yutaro ^a   Yahara, Aiko ^a   Shrestha, Ajaya R ^a   Obika, Satoshi ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Bridged nucleic acids; Nucleosides; Nucleotides; Oligonucleotides; Sugar modifications

Indexed keywords

OLIGONUCLEOTIDE; SINGLE STRANDED DNA; SINGLE STRANDED RNA; SPLEEN EXONUCLEASE; THYMIDINE DERIVATIVE;

ARTICLE; BINDING AFFINITY; BIOCHEMICAL COMPOSITION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME STABILITY; MELTING POINT; MOLECULAR STABILITY; NUCLEIC ACID ANALYSIS; NUCLEIC ACID SYNTHESIS; PROCESS DEVELOPMENT; RNA BINDING; STRUCTURE ANALYSIS; ULTRAVIOLET RADIATION;

AMIDES; DNA; DRUG DESIGN; MOLECULAR STRUCTURE; RNA; THYMIDINE;

EID: 84879005713     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.04.049     Document Type: Article

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