Complementary and Integrative Treatments: Tinnitus

Otolaryngologic Clinics of North America

Volumn 46, Issue 3, 2013, Pages 389-408

  Smith, Gregory S ^a   Romanelli Gobbi, Massi ^b   Gray Karagrigoriou, Elizabeth ^a   Artz, Gregory J ^a  

^a THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Complementary medicine; Herbal supplements; Tinnitus; Transcranial magnetic stimulation

Indexed keywords

ALPRAZOLAM; CYANOCOBALAMIN; DEXAMETHASONE; GABAPENTIN; GARLIC EXTRACT; GINKGO BILOBA EXTRACT; MELATONIN; PUERARIA EXTRACT; ZINC;

ACCIDENTAL INJURY; ACOUSTIC REFLEX; ACUPUNCTURE; ANGULAR GYRUS; ARNOLD CHIARI MALFORMATION; AUDITORY NERVOUS SYSTEM; BLEEDING; BRAIN STEM RESPONSE; CHINESE MEDICINE; DEPRESSION; DIFFERENTIAL DIAGNOSIS; DISEASE SEVERITY; ELECTROSTIMULATION; EVIDENCE BASED MEDICINE; FAINTNESS; FOLLOW UP; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GLOMUS TUMOR; HEARING AID; HEARING IMPAIRMENT; IMPLANTATION; KOREAN MEDICINE; MENIERE DISEASE; MOOD DISORDER; MUSCLE SPASM; NERVE INJURY; OTITIS MEDIA; PATIENT SATISFACTION; PNEUMOTHORAX; POSITRON EMISSION TOMOGRAPHY; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; TEMPORAL CORTEX; TINNITUS; TRANSCRANIAL MAGNETIC STIMULATION; VESTIBULAR EVOKED MYOGENIC POTENTIAL; VOCATIONAL GUIDANCE;

COMPLEMENTARY THERAPIES; DIAGNOSIS, DIFFERENTIAL; HUMANS; INTEGRATIVE MEDICINE; TINNITUS; TRANSCRANIAL MAGNETIC STIMULATION; TREATMENT OUTCOME;

EID: 84878974871     PISSN: 00306665     EISSN: 15578259     Source Type: Journal    
DOI: 10.1016/j.otc.2013.02.005     Document Type: Review

References (103)

1. Cooper J.C. Health and Nutrition Examination Survey of 1971-75: part II. Tinnitus, subjective hearing loss, and well-being. JAm Acad Audiol 1994, 5(1):37-43.
2. Reed G.F. An audiometric study of two hundred cases of subjective tinnitus. AMA Arch Otolaryngol 1960, 71:84-94.
3. Vernon J. The history of masking as applied to tinnitus. JLaryngol Otol Suppl 1981, (4):76-79.
4. Schleuning A.J., Johnson R.M., Vernon J.A. Evaluation of a tinnitus masking program: a follow-up study of 598 patients. Ear Hear 1980, 1(2):71-74.
5. Moller A.R. Similarities between severe tinnitus and chronic pain. JAm Acad Audiol 2000, 11(3):115-124.
6. Moller A.R. Pathophysiology of tinnitus. Otolaryngol Clin North Am 2003, 36(2):249-266. v-vi.
7. Farhadi M., Mahmoudian S., Saddadi F., et al. Functional brain abnormalities localized in 55 chronic tinnitus patients: fusion of SPECT coincidence imaging and MRI. JCereb Blood Flow Metab 2010, 30(4):864-870.
8. Moller A.R. The role of neural plasticity in tinnitus. Prog Brain Res 2007, 166:37-45.
9. Ramachandran V.S., Hirstein W. The perception of phantom limbs. The D.O. Hebb lecture. Brain 1998, 121(Pt 9):1603-1630.
10. Simmel M.L. Phantom experiences following amputation in childhood. JNeurol Neurosurg Psychiatry 1962, 25:69-78.
11. Norena A.J., Eggermont J.J. Changes in spontaneous neural activity immediately after an acoustic trauma: implications for neural correlates of tinnitus. Hear Res 2003, 183(1-2):137-153.
12. Barney R., Bohnker B.K. Hearing thresholds for U.S. Marines: comparison of aviation, combat arms, and other personnel. Aviat Space Environ Med 2006, 77(1):53-56.
13. Helfer T.M., Jordan N.N., Lee R.B. Postdeployment hearing loss in U.S. Army soldiers seen at audiology clinics from April 1, 2003, through March 31, 2004. Am J Audiol 2005, 14(2):161-168.
14. Axelsson A., Sandh A. Tinnitus in noise-induced hearing loss. Br J Audiol 1985, 19(4):271-276.
15. Axelsson A., Jerson T., Lindberg U., et al. Early noise-induced hearing loss in teenage boys. Scand Audiol 1981, 10(2):91-96.
16. Le Prell C.G., Hughes L.F., Miller J.M. Free radical scavengers vitamins A, C, and E plus magnesium reduce noise trauma. Free Radic Biol Med 2007, 42(9):1454-1463.
17. Attias J., Weisz G., Almog S., et al. Oral magnesium intake reduces permanent hearing loss induced by noise exposure. Am J Otolaryngol 1994, 15(1):26-32.
18. Moller A.R., Rollins P.R. The non-classical auditory pathways are involved in hearing in children but not in adults. Neurosci Lett 2002, 319(1):41-44.
19. Moller A.R. Vascular compression of cranial nerves. I. History of the microvascular decompression operation. Neurol Res 1998, 20(8):727-731.
20. De Ridder D., De Mulder G., Verstraeten E., et al. Somatosensory cortex stimulation for deafferentation pain. Acta Neurochir Suppl 2007, 97(Pt 2):67-74.
21. Gerken G.M., Saunders S.S., Paul R.E. Hypersensitivity to electrical stimulation of auditory nuclei follows hearing loss in cats. Hear Res 1984, 13(3):249-259.
22. Møller A.R. Sensory systems: anatomy and physiology 2003, Academic Press, San Diego, CA.
23. Levine R.A. Somatic (craniocervical) tinnitus and the dorsal cochlear nucleus hypothesis. Am J Otolaryngol 1999, 20(6):351-362.
24. Sanchez T.G., da Silva Lima A., Brandão A.L., et al. Somatic modulation of tinnitus: test reliability and results after repetitive muscle contraction training. Ann Otol Rhinol Laryngol 2007, 116(1):30-35.
25. Herraiz C., Toledano A., Diges I. Trans-electrical nerve stimulation (TENS) for somatic tinnitus. Prog Brain Res 2007, 166:389-394.
26. Hoare D.J., Kowalkowski V.L., Kang S., et al. Systematic review and meta-analyses of randomized controlled trials examining tinnitus management. Laryngoscope 2011, 121(7):1555-1564.
27. Henry J.A., Dennis K.C., Schechter M.A. General review of tinnitus: prevalence, mechanisms, effects, and management. JSpeech Lang Hear Res 2005, 48(5):1204-1235.
28. Sismanis A., Smoker W.R. Pulsatile tinnitus: recent advances in diagnosis. Laryngoscope 1994, 104(6 Pt 1):681-688.
29. Sismanis A., Butts F.M., Hughes G.B. Objective tinnitus in benign intracranial hypertension: an update. Laryngoscope 1990, 100:33-36.
30. Sismanis A., Hughes G.B., Abedi E., et al. Otologic symptoms and findings of the pseudotumor cerebri syndrome: a preliminary report. Otolaryngol Head Neck Surg 1985, 93(3):398-402.
31. Hoare D.J., Hall D.A. Clinical guidelines and practice: a commentary on the complexity of tinnitus management. Eval Health Prof 2011, 34(4):413-420.
32. Seabra J.C., Diamantino H., Faria E.A. Neurootological evaluation of tinnitus. Int Tinnitus J 1995, 1(2):93-97.
33. Branstetter B.F., Weissman J.L. The radiologic evaluation of tinnitus. Eur Radiol 2006, 16(12):2792-2802.
34. Ikner C.L., Hassen A.H. The effect of tinnitus on ABR latencies. Ear Hear 1990, 11(1):16-20.
35. Ceranic B.J., Prasher D.K., Luxon L.M. Tinnitus and otoacoustic emissions. Clin Otolaryngol Allied Sci 1995, 20(3):192-200.
36. de Azevedo A.A., Langguth B., de Oliveira P.M., et al. Tinnitus treatment with piribedil guided by electrocochleography and acoustic otoemissions. Otol Neurotol 2009, 30(5):676-680.
37. Newman C.W., Sandridge S.A., Jacobson G.P. Psychometric adequacy of the Tinnitus Handicap Inventory (THI) for evaluating treatment outcome. JAm Acad Audiol 1998, 9(2):153-160.
38. Bauer C.A., Brozoski T.J. Effect of tinnitus retraining therapy on the loudness and annoyance of tinnitus: a controlled trial. Ear Hear 2011, 32(2):145-155.
39. Parazzini M., Del Bo L., Jastreboff M., et al. Open ear hearing aids in tinnitus therapy: an efficacy comparison with sound generators. Int J Audiol 2011, 50(8):548-553.
40. Pisckosz MK, S. Resound Live TS: an innovative tinnitus sound generator device to assist in tinnitus management. 2012.
41. Sweetow R.W., Sabes J.H. Effects of acoustical stimuli delivered through hearing aids on tinnitus. JAm Acad Audiol 2010, 21(7):461-473.
42. Newman C.W., Sandridge S.A. Acomparison of benefit and economic value between two sound therapy tinnitus management options. JAm Acad Audiol 2012, 23(2):126-138.
43. Reavis K.M., Chang J.E., Zeng F.G. Patterned sound therapy for the treatment of tinnitus. Hear J 2010, 63(11):21-24.
44. Pascual-Leone A., Valls-Solé J., Wassermann E.M., et al. Responses to rapid-rate transcranial magnetic stimulation of the human motor cortex. Brain 1994, 117(Pt 4):847-858.
45. Bestmann S., Ruff C.C., Blakemore C., et al. Spatial attention changes excitability of human visual cortex to direct stimulation. Curr Biol 2007, 17(2):134-139.
46. Langguth B., de Ridder D., Dornhoffer J.L., et al. Controversy: does repetitive transcranial magnetic stimulation/transcranial direct current stimulation show efficacy in treating tinnitus patients?. Brain Stimul 2008, 1(3):192-205.
47. Khedr E.M., Rothwell J.C., Ahmed M.A., et al. Effect of daily repetitive transcranial magnetic stimulation for treatment of tinnitus: comparison of different stimulus frequencies. JNeurol Neurosurg Psychiatry 2008, 79(2):212-215.
48. Quaranta N., Wagstaff S., Baguley D.M. Tinnitus and cochlear implantation. Int J Audiol 2004, 43(5):245-251.
49. Brackmann D.E. Reduction of tinnitus in cochlear-implant patients. JLaryngol Otol Suppl 1981, (4):163-165.
50. Stephens S.D. The treatment of tinnitus-a historical perspective. JLaryngol Otol 1984, 98(10):963-972.
51. Bauer C.A., Brozoski T.J., Myers K. Primary afferent dendrite degeneration as a cause of tinnitus. JNeurosci Res 2007, 85(7):1489-1498.
52. Bauer C.A. Mechanisms of tinnitus generation. Curr Opin Otolaryngol Head Neck Surg 2004, 12(5):413-417.
53. Brozoski T.J., Spires T.J., Bauer C.A. Vigabatrin, a GABA transaminase inhibitor, reversibly eliminates tinnitus in an animal model. JAssoc Res Otolaryngol 2007, 8(1):105-118.
54. Shulman A., Strashun A.M., Seibyl J.P., et al. Benzodiazepine receptor deficiency and tinnitus. Int Tinnitus J 2000, 6(2):98-111.
55. Millet P., Graf C., Moulin M., et al. SPECT quantification of benzodiazepine receptor concentration using a dual-ligand approach. JNucl Med 2006, 47(5):783-792.
56. Shulman A., Strashun A.M., Afriyie M., et al. SPECT imaging of brain and tinnitus-neurotologic/neurologic implications. Int Tinnitus J 1995, 1(1):13-29.
57. Piccirillo J.F., Finnell J., Vlahiotis A., et al. Relief of idiopathic subjective tinnitus: is gabapentin effective?. Arch Otolaryngol Head Neck Surg 2007, 133(4):390-397.
58. Otsuka K., Pulec J.L., Suzuki M. Assessment of intravenous lidocaine for the treatment of subjective tinnitus. Ear Nose Throat J 2003, 82(10):781-784.
59. Baguley D.M., Jones S., Wilkins I., et al. The inhibitory effect of intravenous lidocaine infusion on tinnitus after translabyrinthine removal of vestibular schwannoma: a double-blind, placebo-controlled, crossover study. Otol Neurotol 2005, 26(2):169-176.
60. Thompson G.C., Thompson A.M., Garrett K.M., et al. Serotonin and serotonin receptors in the central auditory system. Otolaryngol Head Neck Surg 1994, 110(1):93-102.
61. Dobie R.A. Areview of randomized clinical trials in tinnitus. Laryngoscope 1999, 109(8):1202-1211.
62. Silverstein H., Choo D., Rosenberg S.I., et al. Intratympanic steroid treatment of inner ear disease and tinnitus (preliminary report). Ear Nose Throat J 1996, 75(8):468-471. 474, 476 passim.
63. Shulman A., Goldstein B. Intratympanic drug therapy with steroids for tinnitus control: a preliminary report. Int Tinnitus J 2000, 6(1):10-20.
64. Araujo M.F., Oliveira C.A., Bahmad F.M. Intratympanic dexamethasone injections as a treatment for severe, disabling tinnitus: does it work?. Arch Otolaryngol Head Neck Surg 2005, 131(2):113-117.
65. Topak M., Sahin-Yilmaz A., Ozdoganoglu T., et al. Intratympanic methylprednisolone injections for subjective tinnitus. JLaryngol Otol 2009, 123(11):1221-1225.
66. She W., Dai Y., Du X., et al. Treatment of subjective tinnitus: a comparative clinical study of intratympanic steroid injection vs. oral carbamazepine. Med Sci Monit 2009, 15(6):PI35-PI39.
67. Shim H.J., Song S.J., Choy A.Y., et al. Comparison of various treatment modalities for acute tinnitus. Laryngoscope 2011, 121(12):2619-2625.
68. Drew S., Davies E. Effectiveness of Ginkgo biloba in treating tinnitus: double blind, placebo controlled trial. BMJ 2001, 322(7278):73.
69. Sierpina V.S., Wollschlaeger B., Blumenthal M. Ginkgo biloba. Am Fam Physician 2003, 68(5):923-926.
70. Karkos P.D., Leong S.C., Arya A.K., et al. 'Complementary ENT': a systematic review of commonly used supplements. JLaryngol Otol 2007, 121(8):779-782.
71. Meyer B. Multicenter randomized double-blind drug vs. placebo study of the treatment of tinnitus with Ginkgo biloba extract. Presse Med 1986, 15(31):1562-1564. [in French].
72. von Boetticher A. Ginkgo biloba extract in the treatment of tinnitus: a systematic review. Neuropsychiatr Dis Treat 2011, 7:441-447.
73. Holstein N. Ginkgo special extract EGb 761 in tinnitus therapy. An overview of results of completed clinical trials. Fortschr Med Orig 2001, 118(4):157-164. [inGerman].
74. Morgenstern C., Biermann E. The efficacy of Ginkgo special extract EGb 761 in patients with tinnitus. Int J Clin Pharmacol Ther 2002, 40(5):188-197.
75. Jastreboff P.J., Zhou S., Jastreboff M.M., et al. Attenuation of salicylate-induced tinnitus by Ginkgo biloba extract in rats. Audiol Neurootol 1997, 2(4):197-212.
76. Rejali D., Sivakumar A., Balaji N. Ginkgo biloba does not benefit patients with tinnitus: a randomized placebo-controlled double-blind trial and meta-analysis of randomized trials. Clin Otolaryngol Allied Sci 2004, 29(3):226-231.
77. Ernst E., Stevinson C. Ginkgo biloba for tinnitus: a review. Clin Otolaryngol Allied Sci 1999, 24(3):164-167.
78. Shambaugh G.E. Zinc for tinnitus, imbalance, and hearing loss in the elderly. Am J Otol 1986, 7(6):476-477.
79. Alexander T.H., Davidson T.M. Intranasal zinc and anosmia: the zinc-induced anosmia syndrome. Laryngoscope 2006, 116(2):217-220.
80. Cho G.S., Han M.W., Lee B., et al. Zinc deficiency may be a cause of burning mouth syndrome as zinc replacement therapy has therapeutic effects. JOral Pathol Med 2010, 39(9):722-727.
81. Coelho C.B., Tyler R., Hansen M. Zinc as a possible treatment for tinnitus. Prog Brain Res 2007, 166:279-285.
82. Arda H.N., Tuncel U., Akdogan O., et al. The role of zinc in the treatment of tinnitus. Otol Neurotol 2003, 24(1):86-89.
83. Ochi K., Ohashi T., Kinoshita H., et al. The serum zinc level in patients with tinnitus and the effect of zinc treatment. Nihon Jibiinkoka Gakkai Kaiho 1997, 100(9):915-919. [in Japanese].
84. Paaske P.B., Pedersen C.B., Kiems G., et al. Zinc in the management of tinnitus. Placebo-controlled trial. Ann Otol Rhinol Laryngol 1991, 100(8):647-649.
85. Yetiser S., Tosun F., Satar B., et al. The role of zinc in management of tinnitus. Auris Nasus Larynx 2002, 29(4):329-333.
86. Pirodda A., Raimondi M.C., Ferri G.G. Exploring the reasons why melatonin can improve tinnitus. Med Hypotheses 2010, 75(2):190-191.
87. Rosenberg S.I., Silverstein H., Rowan P.T., et al. Effect of melatonin on tinnitus. Laryngoscope 1998, 108(3):305-310.
88. Hurtuk A., Dome C., Holloman C.H., et al. Melatonin: can it stop the ringing?. Ann Otol Rhinol Laryngol 2011, 120(7):433-440.
89. Lopez-Gonzalez M.A., Santiago A.M., Esteban-Ortega F. Sulpiride and melatonin decrease tinnitus perception modulating the auditolimbic dopaminergic pathway. JOtolaryngol 2007, 36(4):213-219.
90. Megwalu U.C., Finnell J.E., Piccirillo J.F. The effects of melatonin on tinnitus and sleep. Otolaryngol Head Neck Surg 2006, 134(2):210-213.
91. Seabra M.L., Bignotto M., Pinto L.R., et al. Randomized, double-blind clinical trial, controlled with placebo, of the toxicology of chronic melatonin treatment. JPineal Res 2000, 29(4):193-200.
92. Shemesh Z., Attias J., Ornan M., et al. Vitamin B12 deficiency in patients with chronic-tinnitus and noise-induced hearing loss. Am J Otolaryngol 1993, 14(2):94-99.
93. Seidman M.D., Babu S. Alternative medications and other treatments for tinnitus: facts from fiction. Otolaryngol Clin North Am 2003, 36(2):359-381.
94. Linde K., ter Riet G., Hondras M., et al. Systematic reviews of complementary therapies-an annotated bibliography. Part 2: herbal medicine. BMC Complement Altern Med 2001, 1:5.
95. Kim N.K., Lee D.H., Lee J.H., et al. Bojungikgitang and banhabaekchulchonmatang in adult patients with tinnitus, a randomized, double-blind, three-arm, placebo-controlled trial-study protocol. Trials 2010, 11:34.
96. Zheng Y., Vagal S., Zhu X.X., et al. The effects of the Chinese herbal medicine EMF01 on salicylate-induced tinnitus in rats. JEthnopharmacol 2010, 128(2):545-548.
97. Okamoto H., Okami T., Ikeda M., et al. Effects of Yoku-kan-san on undifferentiated somatoform disorder with tinnitus. Eur Psychiatry 2005, 20(1):74-75.
98. Okada D.M., Onishi E.T., Chami F.L., et al. Acupuncture for tinnitus immediate relief. Braz J Otorhinolaryngol 2006, 72(2):182-186.
99. Tan K.Q., Zhang C., Liu M.X., et al. Comparative study on therapeutic effects of acupuncture, Chinese herbs and Western medicine on nervous tinnitus. Zhongguo Zhen Jiu 2007, 27(4):249-251. [in Chinese].
100. Park J., White A.R., Ernst E. Efficacy of acupuncture as a treatment for tinnitus: a systematic review. Arch Otolaryngol Head Neck Surg 2000, 126(4):489-492.
101. Whedon J. Reduction of tinnitus by spinal manipulation in a patient with presumptive rotational vertebral artery occlusion syndrome: a case report. Altern Ther Health Med 2006, 12(3):14-17.
102. Alcantara J., Plaugher G., Klemp D.D., et al. Chiropractic care of a patient with temporomandibular disorder and atlas subluxation. JManipulative Physiol Ther 2002, 25(1):63-70.
103. Hulse M., Holzl M. The efficiency of spinal manipulation in otorhinolaryngology. A retrospective long-term study. HNO 2004, 52(3):227-234. [in German].