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Edited by Henderson D, Prasher D, Kopke R, Salvi RJ, Hamernik R. London: NRN
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Caspary DM, Salvi RJ, Helfert RH, et al.: Neuropharmacology of noise induced hearing loss in brainstem auditory structures. In Noise Induced Hearing Loss: Mechanisms of Damage and Means of Prevention. Edited by Henderson D, Prasher D, Kopke R, Salvi RJ, Hamernik R. London: NRN; 2001:169-186.
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Caspary, D.M.1
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Electrical suppression of tinnitus with high-rate pulse trains
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Rubinstein JT, Tyler RS, Johnson A, Brown CJ: Electrical suppression of tinnitus with high-rate pulse trains. Otology Neurotology 2003, 24:478-485. This report of a novel stimulation paradigm that is effective in suppressing some forms of tinnitus holds promise for future developments in treatment. Understanding the mechanisms responsible for nonresponders would also be very revealing.
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Otology Neurotology
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Rubinstein, J.T.1
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Noise trauma alters D-[3H]aspartate release and AMPA binding in chinchilla cochlear nucleus
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Muly SM, Gross JS, Potashner SJ: Noise trauma alters D-[3H]aspartate release and AMPA binding in chinchilla cochlear nucleus. J Neurosci Res 2004, 75:585-596. The implications for changes in both excitatory and inhibitory neurotransmitter regulation after cochlear trauma will be important in future work developing pharmacologic tinnitus interventions.
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Muly, S.M.1
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Elevated fusiform cell activity in the dorsal cochlear nucleus of chinchillas with psychophysical evidence of tinnitus
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Brozoski TJ, Bauer CA, Caspary DM: Elevated fusiform cell activity in the dorsal cochlear nucleus of chinchillas with psychophysical evidence of tinnitus. J Neurosci 2002, 22:2383-2390.
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Brozoski, T.J.1
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Habituation deficit in auditory event-related potentials in tinnitus complainers
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Walpurger V, Hebing-Lennartz G, Denecke H, Pietrowsky R: Habituation deficit in auditory event-related potentials in tinnitus complainers. Hear Res 2003, 181:57-64. This report very elegantly demonstrates what may represent a fundamental difference subserving the affective from the sensory component of tinnitus.
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Walpurger, V.1
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Guide to conducting tinnitus retraining therapy initial and follow-up interviews
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Phantom-limb pain as a perceptual correlate of cortical reorganization following arm amputation
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Plasticity in the frequency representation of primary auditory cortex following discrimination training in adult owl monkeys
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Psychoacoustic characterization of the tinnitus spectrum: Implications for the underlying mechanisms of tinnitus
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Norena A, Micheyl C, Chéry-Croze S, Collet L: Psychoacoustic characterization of the tinnitus spectrum: implications for the underlying mechanisms of tinnitus. Audiol Neurootol 2002, 7:358-369.
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Adaptive plasticity of loudness induced by chronic attenuation and enhancement of the acoustic background
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Formby C, Sherlock LP, Gold SL: Adaptive plasticity of loudness induced by chronic attenuation and enhancement of the acoustic background. J Acoust Soc Am 2003, 114:55-58. The authors cleverly demonstrated a fundamental process of auditory plasticity that is a key feature in the popular treatment of tinnitus retraining therapy.
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Formby, C.1
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Some forms of tinnitus may involve the extralemniscal auditory pathway
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Moller AR, Moller MB, Yokota M: Some forms of tinnitus may involve the extralemniscal auditory pathway. Laryngoscope 1992, 102:1165-1171.
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Levine RA, Abel M, Cheng H: CNS somatosensory-auditory interactions elicit or modulate tinnitus. Exp Brain Res 2003, 153:643-648. This extension of the author's initial hypothesis of somatosensory modulation of tinnitus has important implications for understanding and treating tinnitus.
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Effects of trigeminal ganglion stimulation on unit activity in the ventral cochlear nucleus of the guinea pig
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Shore SE, El-Kashlan HK, Lu J: Effects of trigeminal ganglion stimulation on unit activity in the ventral cochlear nucleus of the guinea pig. Neuroscience 2003, 119:1085-1101. This work provides strong evidence for the functional connectivity between the trigeminal ganglion and the cochlear nucleus, and provides an important link supporting Levine's clinical observations.
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Effects of trigeminal ganglion stimulation on the central auditory system
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El-Kashlan HK, Shore SE: Effects of trigeminal ganglion stimulation on the central auditory system. Hear Res 2004, 189:25-30. The authors have elegantly demonstrated the link between the trigeminal system and higher centers within the auditory pathway. This also is an interesting demonstration supporting the somatosensory hypothesis of Levine.
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Hear Res
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Vass Z, Dai CF, Steyger PS, et al.: Co-localization of the vanilloid capsaicin receptor and substance P in sensory nerve fibers innervating cochlear and vertebro-basilar arteries. Neuroscience 2004, 124:919-927. This is a landmark study linking a functional relationship between trigeminal neurons and vascular permeability in the cochlea and auditory brainstem. The implications for inflammatory factors modulating tinnitus open a new field of investigation regarding mechanisms and treatments.
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Neuroscience
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Vass, Z.1
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Hear Res
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Increases in spontaneous activity in the dorsal cochlear nucleus following exposure to high intensity sound: A possible neural correlate of tinnitus
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The effect of bilateral DCN ablation on behavioral evidence of tinnitus in rats
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Molecular Mechanisms in Central Auditory Function
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Brozoski, T.J.1
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