CD8+ T cells characterize early smoking-related airway pathology in patients with asthma

Respiratory Medicine

Volumn 107, Issue 7, 2013, Pages 959-966

  Ravensberg, A Janneke ^a   Slats, Annelies M ^a   Van Wetering, Sandra ^a   Janssen, Kirsten ^a   Van Wijngaarden, Simone ^a   De Jeu, Ronald ^a   Rabe, Klaus F ^a,b   Sterk, Peter J ^a,c   Hiemstra, Pieter S ^a  

^a Rijnlands Rehabilitation Center   (Netherlands)

^b KRANKENHAUS GROSSHANSDORF   (Germany)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Airway epithelium; Airway inflammation; Asthma; CD8+ T lymphocyte; Smoking

Indexed keywords

STEROID;

ADULT; AIRWAY; ARTICLE; ASTHMA; BRONCHUS BIOPSY; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MALE; MILD INTERMITTENT ASTHMA; MILD PERSISTENT ASTHMA; NEUTROPHIL; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; SMOKING;

ADULT; ASTHMA; BIOPSY; BRONCHI; BRONCHITIS; BRONCHOSCOPY; CD4-CD8 RATIO; CD8-POSITIVE T-LYMPHOCYTES; CROSS-SECTIONAL STUDIES; DISEASE PROGRESSION; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; RESPIRATORY MUCOSA; SMOKING; YOUNG ADULT;

EID: 84878954911     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2013.03.018     Document Type: Article

References (49)

1. N.T. Vozoris, and M.B. Stanbrook Smoking prevalence, behaviours, and cessation among individuals with COPD or asthma Respir Med 105 2011 477 484
2. I. Cerveri, L. Cazzoletti, A.G. Corsico, A. Marcon, R. Niniano, and A. Grosso The impact of cigarette smoking on asthma: a population-based international cohort study Int Arch Allergy Immunol 158 2012 175 183
3. R. Chaudhuri, C. McSharry, A. McCoard, E. Livingston, E. Hothersall, and M. Spears Role of symptoms and lung function in determining asthma control in smokers with asthma Allergy 63 2008 132 135 (Pubitemid 350198240)
4. J. Clatworthy, D. Price, D. Ryan, J. Haughney, and R. Horne The value of self-report assessment of adherence, rhinitis and smoking in relation to asthma control Prim Care Respir J 18 2009 300 305
5. G.W. Chalmers, K.J. Macleod, S.A. Little, L.J. Thomson, C.P. McSharry, and N.C. Thomson Influence of cigarette smoking on inhaled corticosteroid treatment in mild asthma Thorax 57 2002 226 230 (Pubitemid 34214408)
6. S.C. Lazarus, V.M. Chinchilli, N.J. Rollings, H.A. Boushey, R. Cherniack, and T.J. Craig Smoking affects response to inhaled corticosteroids or leukotriene receptor antagonists in asthma Am J Respir Crit Care Med 175 2007 783 790 (Pubitemid 46631789)
7. A.L. James, L.J. Palmer, E. Kicic, P.S. Maxwell, S.E. Lagan, and G.F. Ryan Decline in lung function in the Busselton Health Study: the effects of asthma and cigarette smoking Am J Respir Crit Care Med 171 2005 109 114 (Pubitemid 40105408)
8. P. Lange, H. Scharling, C.S. Ulrik, and J. Vestbo Inhaled corticosteroids and decline of lung function in community residents with asthma Thorax 61 2006 100 104 (Pubitemid 43235424)
9. P.M. O'Byrne, C.J. Lamm, W.W. Busse, W.C. Tan, and S. Pedersen The effects of inhaled budesonide on lung function in smokers and nonsmokers with mild persistent asthma Chest 136 2009 1514 1520
10. A. Tamimi, D. Serdarevic, and N.A. Hanania The effects of cigarette smoke on airway inflammation in asthma and COPD: therapeutic implications Respir Med 106 2012 319 328
11. K. Hiroshima, A. Iyoda, K. Shibuya, H. Hoshino, Y. Haga, and T. Toyozaki Evidence of neoangiogenesis and an increase in the number of proliferating cells within the bronchial epithelium of smokers Cancer 95 2002 1539 1545
12. G. Mathe, G. Santelli, J. Gouveia, G. Lemaigre, J.L. Misset, and F. Gros Correlation of bronchial epidermoid metaplasia with level of tobacco consumption in heavy smokers Cancer Detect Prev 9 1986 79 81
13. D.E. Niewoehner, J. Kleinerman, and D.B. Rice Pathologic changes in the peripheral airways of young cigarette smokers N Engl J Med 291 1974 755 758
14. M.G. Cosio, K.A. Hale, and D.E. Niewoehner Morphologic and morphometric effects of prolonged cigarette smoking on the small airways Am Rev Respir Dis 122 1980 265-21
15. E.L. van Rensen, J.K. Sont, C.E. Evertse, L.N. Willems, T. Mauad, and P.S. Hiemstra Bronchial CD8 cell infiltrate and lung function decline in asthma Am J Respir Crit Care Med 172 2005 837 841 (Pubitemid 41369066)
16. M. Saetta, S. Baraldo, L. Corbino, G. Turato, F. Braccioni, and F. Rea CD8+ve cells in the lungs of smokers with chronic obstructive pulmonary disease Am J Respir Crit Care Med 160 1999 711 717 (Pubitemid 29380694)
17. B.E. Lams, A.R. Sousa, P.J. Rees, and T.H. Lee Subepithelial immunopathology of the large airways in smokers with and without chronic obstructive pulmonary disease Eur Respir J 15 2000 512 516 (Pubitemid 30158188)
18. L.P. Boulet, C. Lemiere, F. Archambault, G. Carrier, M.C. Descary, and F. Deschesnes Smoking and asthma: clinical and radiologic features, lung function, and airway inflammation Chest 129 2006 661 668
19. J. St Laurent, C. Bergeron, N. Page, C. Couture, M. Laviolette, and L.P. Boulet Influence of smoking on airway inflammation and remodelling in asthma Clin Exp Allergy 38 2008 1582 1589
20. G.W. Chalmers, K.J. Macleod, L. Thomson, S.A. Little, C. McSharry, and N.C. Thomson Smoking and airway inflammation in patients with mild asthma Chest 120 2001 1917 1922 (Pubitemid 34053454)
21. M. Broekema, N.H. ten Hacken, F. Volbeda, M.E. Lodewijk, M.N. Hylkema, and D.S. Postma Airway epithelial changes in smokers but not in ex-smokers with asthma Am J Respir Crit Care Med 180 2009 1170 1178
22. P.G. Gibson, and J.L. Simpson The overlap syndrome of asthma and COPD: what are its features and how important is it? Thorax 64 2009 728 735
23. National Heart Lung, Blood Institute, and World Health Organization NHLBI/WHO workshop report: global initiative for asthma management and prevention (updated November 2006) 1991 National Institutes of Health Bethesda, MD Publication no. 95-3659. Available from: http://www.ginasthma.org
24. A.M. Slats, K. Janssen, A. van Schadewijk, D.T. van der Plas, R. Schot, and J.G. van den Aardweg Bronchial inflammation and airway responses to deep inspiration in asthma and chronic obstructive pulmonary disease Am J Respir Crit Care Med 176 2007 121 128 (Pubitemid 47057847)
25. M.R. Miller, J. Hankinson, V. Brusasco, F. Burgos, R. Casaburi, and A. Coates Standardisation of spirometry Eur Respir J 26 2005 319 338 (Pubitemid 41079078)
26. P.J. Sterk, L.M. Fabbri, P.H. Quanjer, D.W. Cockcroft, P.M. O'Byrne, and S.D. Anderson Airway responsiveness. Standardized challenge testing with pharmacological, physical and sensitizing stimuli in adults. Report working party standardization of lung function tests, European community for steel and coal. Official statement of the european respiratory society Eur Respir J Suppl 16 1993 53 83
27. A.J. Ravensberg, E.L. van Rensen, D.C. Grootendorst, J. de Kluijver, Z. Diamant, and F.L. Ricciardolo Validated safety predictions of airway responses to house dust mite in asthma Clin Exp Allergy 37 2007 100 107 (Pubitemid 46011064)
28. J. de Kluijver, J.A. Schrumpf, C.E. Evertse, J.K. Sont, P.J. Roughley, and K.F. Rabe Bronchial matrix and inflammation respond to inhaled steroids despite ongoing allergen exposure in asthma Clin Exp Allergy 35 2005 1361 1369
29. P. Jeffery, S. Holgate, and S. Wenzel Methods for the assessment of endobronchial biopsies in clinical research: application to studies of pathogenesis and the effects of treatment Am J Respir Crit Care Med 168 2003 S1 17
30. T.S. Lapperre, J.K. Sont, A. van Schadewijk, M.M. Gosman, D.S. Postma, and I.M. Bajema Smoking cessation and bronchial epithelial remodelling in COPD: a cross-sectional study Respir Res 8 2007 85
31. 1 Am J Respir Crit Care Med 155 1997 852 857 (Pubitemid 27133393)
32. A. Ekberg-Jansson, B. Andersson, E. Avra, O. Nilsson, and C.G. Lofdahl The expression of lymphocyte surface antigens in bronchial biopsies, bronchoalveolar lavage cells and blood cells in healthy smoking and never-smoking men, 60 years old Respir Med 94 2000 264 272 (Pubitemid 30198077)
33. G.H. Blake, T.D. Abell, and W.G. Stanley Cigarette smoking and upper respiratory infection among recruits in basic combat training Ann Intern Med 109 1988 198 202
34. S. Cohen, D.A. Tyrrell, M.A. Russell, M.J. Jarvis, and A.P. Smith Smoking, alcohol consumption, and susceptibility to the common cold Am J Public Health 83 1993 1277 1283 (Pubitemid 23262033)
35. M. Tsoumakidou, W. Elston, J. Zhu, Z. Wang, E. Gamble, and N.M. Siafakas Cigarette smoking alters bronchial mucosal immunity in asthma Am J Respir Crit Care Med 175 2007 919 925 (Pubitemid 46684702)
36. R.J. Hogan, L.S. Cauley, K.H. Ely, T. Cookenham, A.D. Roberts, and J.W. Brennan Long-term maintenance of virus-specific effector memory CD8+ T cells in the lung airways depends on proliferation J Immunol 169 2002 4976 4981 (Pubitemid 35217164)
37. T. Maeno, A.M. Houghton, P.A. Quintero, S. Grumelli, C.A. Owen, and S.D. Shapiro CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice J Immunol 178 2007 8090 8096 (Pubitemid 46898081)
38. R.E. Kanner, N.R. Anthonisen, and J.E. Connett Lower respiratory illnesses promote FEV(1) decline in current smokers but not ex-smokers with mild chronic obstructive pulmonary disease: results from the lung health study Am J Respir Crit Care Med 164 2001 358 364 (Pubitemid 32778199)
39. T.R. Bai, J.M. Vonk, D.S. Postma, and H.M. Boezen Severe exacerbations predict excess lung function decline in asthma Eur Respir J 30 2007 452 456 (Pubitemid 351182067)
40. C.L. Ordonez, R. Khashayar, H.H. Wong, R. Ferrando, R. Wu, and D.M. Hyde Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression Am J Respir Crit Care Med 163 2001 517 523 (Pubitemid 32158539)
41. S.M. Puddicombe, R. Polosa, A. Richter, M.T. Krishna, P.H. Howarth, and S.T. Holgate Involvement of the epidermal growth factor receptor in epithelial repair in asthma FASEB J 14 2000 1362 1374 (Pubitemid 30439745)
42. A. Barbato, G. Turato, S. Baraldo, E. Bazzan, F. Calabrese, and C. Panizzolo Epithelial damage and angiogenesis in the airways of children with asthma Am J Respir Crit Care Med 174 2006 975 981 (Pubitemid 44684445)
43. C. Xiao, S.M. Puddicombe, S. Field, J. Haywood, V. Broughton-Head, and I. Puxeddu Defective epithelial barrier function in asthma J Allergy Clin Immunol 128 2011 549 556
44. S.M. Puddicombe, C. Torres-Lozano, A. Richter, F. Bucchieri, J.L. Lordan, and P.H. Howarth Increased expression of p21(waf) cyclin-dependent kinase inhibitor in asthmatic bronchial epithelium Am J Respir Cell Mol Biol 28 2003 61 68 (Pubitemid 36017051)
45. T.L. Hackett, G.K. Singhera, F. Shaheen, P. Hayden, G.R. Jackson, and R.G. Hegele Intrinsic phenotypic differences of asthmatic epithelium and its inflammatory responses to respiratory syncytial virus and air pollution Am J Respir Cell Mol Biol 45 2011 1090 1100
46. R.J. Freishtat, A.M. Watson, A.S. Benton, S.F. Iqbal, D.K. Pillai, and M.C. Rose Asthmatic airway epithelium is intrinsically inflammatory and mitotically dyssynchronous Am J Respir Cell Mol Biol 44 2011 863 869
47. F. Luppi, J. Aarbiou, S. van Wetering, I. Rahman, W.I. De Boer, and K.F. Rabe Effects of cigarette smoke condensate on proliferation and wound closure of bronchial epithelial cells in vitro: role of glutathione Respir Res 6 2005 140
48. Y.E. Miller, P. Blatchford, D.S. Hyun, R.L. Keith, T.C. Kennedy, and H. Wolf Bronchial epithelial Ki-67 index is related to histology, smoking, and gender, but not lung cancer or chronic obstructive pulmonary disease Cancer Epidemiol Biomarkers Prev 16 2007 2425 2431 (Pubitemid 351196376)
49. R. Chaudhuri, E. Livingston, A.D. McMahon, J. Lafferty, I. Fraser, and M. Spears Effects of smoking cessation on lung function and airway inflammation in smokers with asthma Am J Respir Crit Care Med 174 2006 127 133 (Pubitemid 44015385)