메뉴 건너뛰기




Volumn 93, Issue 4, 2013, Pages 398-400

A novel quinoline derivative that inhibits mycobacterial FtsZ

Author keywords

Tuberculosis FtsZ Quinoline

Indexed keywords

6 CHLORO 2 METHYL N(4 PROPOXYPHENYL)QUINOLIN 4 AMINE; FTSZ PROTEIN; N METHYL 4 PROPOXYANILINE; QUINOLINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 84878937952     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2013.04.002     Document Type: Article
Times cited : (28)

References (29)
  • 1
  • 2
    • 70350764818 scopus 로고    scopus 로고
    • Discovery and validation of new antitubercular compounds as potential drug leads and probes
    • R.C. Goldman, and B.E. Laughon Discovery and validation of new antitubercular compounds as potential drug leads and probes Tuberculosis (Edinb) 89 2009 331 333
    • (2009) Tuberculosis (Edinb) , vol.89 , pp. 331-333
    • Goldman, R.C.1    Laughon, B.E.2
  • 6
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: Confronting the challenges of antibacterial discovery
    • D.J. Payne, M.N. Gwynn, D.J. Holmes, and D.L. Pompliano Drugs for bad bugs: confronting the challenges of antibacterial discovery Nat Rev Drug Discov 6 2007 29 40
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3    Pompliano, D.L.4
  • 8
    • 84859075290 scopus 로고    scopus 로고
    • Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis
    • V. Usha, J.V. Hobrath, S.S. Gurcha, R.C. Reynolds, and G.S. Besra Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis PLOS One 7 2012 e33886
    • (2012) PLOS One , vol.7 , pp. 33886
    • Usha, V.1    Hobrath, J.V.2    Gurcha, S.S.3    Reynolds, R.C.4    Besra, G.S.5
  • 10
    • 64549094601 scopus 로고    scopus 로고
    • Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating
    • A. Lilienkampf, J. Mao, B. Wan, Y. Wang, S.G. Franzblau, and A.P. Kozikowski Structure-activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating Mycobacterium Tuberculosis J Med Chem 52 2009 2109 2118
    • (2009) Mycobacterium Tuberculosis J Med Chem , vol.52 , pp. 2109-2118
    • Lilienkampf, A.1    Mao, J.2    Wan, B.3    Wang, Y.4    Franzblau, S.G.5    Kozikowski, A.P.6
  • 11
    • 49649095678 scopus 로고    scopus 로고
    • Design, synthesis, and pharmacological evaluation of mefloquine-based ligands as novel antituberculosis agents
    • J. Mao, Y. Wang, B. Wan, A.P. Kozikowski, and S.G. Franzblau Design, synthesis, and pharmacological evaluation of mefloquine-based ligands as novel antituberculosis agents ChemMedChem 2 2007 1624 1630
    • (2007) ChemMedChem , vol.2 , pp. 1624-1630
    • Mao, J.1    Wang, Y.2    Wan, B.3    Kozikowski, A.P.4    Franzblau, S.G.5
  • 12
    • 33746280567 scopus 로고    scopus 로고
    • Design, synthesis, and SAR studies of mefloquine-based ligands as potential antituberculosis agents
    • S. Jayaprakash, Y. Iso, B. Wan, S.G. Franzblau, and A.P. Kozikowski Design, synthesis, and SAR studies of mefloquine-based ligands as potential antituberculosis agents ChemMedChem 1 2006 593 597
    • (2006) ChemMedChem , vol.1 , pp. 593-597
    • Jayaprakash, S.1    Iso, Y.2    Wan, B.3    Franzblau, S.G.4    Kozikowski, A.P.5
  • 15
    • 65149091722 scopus 로고    scopus 로고
    • Adam Willardsen J, Anderson MB, Mather G, Pleiman CM, Kasibhatla S, Tseng B, Drewe J, Cai SX. Discovery of N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4- amine, a potent apoptosis inducer and efficacious anticancer agent with high blood brain barrier penetration
    • N. Sirisoma, A. Pervin, H. Zhang, and S. Jiang Adam Willardsen J, Anderson MB, Mather G, Pleiman CM, Kasibhatla S, Tseng B, Drewe J, Cai SX. Discovery of N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine, a potent apoptosis inducer and efficacious anticancer agent with high blood brain barrier penetration J Med Chem 52 2009 2341 2351
    • (2009) J Med Chem , vol.52 , pp. 2341-2351
    • Sirisoma, N.1    Pervin, A.2    Zhang, H.3    Jiang, S.4
  • 17
    • 84862851713 scopus 로고    scopus 로고
    • The development of FtsZ inhibitors as potential antibacterial agents
    • S. Ma, and S. Ma The development of FtsZ inhibitors as potential antibacterial agents Chem Med Chem 7 2012 1161 1172
    • (2012) Chem Med Chem , vol.7 , pp. 1161-1172
    • Ma, S.1    Ma, S.2
  • 22
    • 29444442409 scopus 로고    scopus 로고
    • Synthesis of antimicrobial natural products targeting FtsZ: (±)-dichamanetin and (±)-2'''-hydroxy-5''-benzylisouvarinol-B
    • G. Urgaonkar, S.L.H. Pierre, I. Meir, H. Lund, D.R. Chaudhuri, and J.T. Shaw Synthesis of antimicrobial natural products targeting FtsZ: (±)-dichamanetin and (±)-2'''-hydroxy-5''-benzylisouvarinol-B Org Lett 7 2005 5609 5612
    • (2005) Org Lett , vol.7 , pp. 5609-5612
    • Urgaonkar, G.1    Pierre, S.L.H.2    Meir, I.3    Lund, H.4    Chaudhuri, D.R.5    Shaw, J.T.6
  • 24
    • 4143110291 scopus 로고    scopus 로고
    • Targeting cell division: Small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality
    • D.N. Margailt, L. Romberg, R.B. Mets, A.M. Hebert, T.J. Mitchinson, M.W. Krischner, and D.R. Chaudhuri Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality Proc Natl Acad Sci USA 101 2004 11821 11826
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11821-11826
    • Margailt, D.N.1    Romberg, L.2    Mets, R.B.3    Hebert, A.M.4    Mitchinson, T.J.5    Krischner, M.W.6    Chaudhuri, D.R.7
  • 25
    • 0028872562 scopus 로고
    • FtsZ, a prokaryotic homolog of tubulin
    • H.P. Erickson FtsZ, a prokaryotic homolog of tubulin Cell 80 1995 367 370
    • (1995) Cell , vol.80 , pp. 367-370
    • Erickson, H.P.1
  • 28
    • 0014353168 scopus 로고
    • Synthesis of potential antimalarial agents. II. 6,8-Disubstituted pyrido[2,3-b]pyrazines
    • C. Temple, J.D. Rose, R.D. Elliot, and J.A. Montgomery Synthesis of potential antimalarial agents. II. 6,8-Disubstituted pyrido[2,3-b]pyrazines J Med Chem 11 1968 1216 1218
    • (1968) J Med Chem , vol.11 , pp. 1216-1218
    • Temple, C.1    Rose, J.D.2    Elliot, R.D.3    Montgomery, J.A.4
  • 29
    • 0141807324 scopus 로고
    • Monomethylation of aromatic amines via sodium borohydride mediated carbon-nitrogen bond cleavage
    • S.B. Kadin Monomethylation of aromatic amines via sodium borohydride mediated carbon-nitrogen bond cleavage J Org Chem 38 1973 1348 1350
    • (1973) J Org Chem , vol.38 , pp. 1348-1350
    • Kadin, S.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.