Increased genome instability in human DNA segments with self-chains: Homology-induced structural variations via replicative mechanisms

Human Molecular Genetics

Volumn 22, Issue 13, 2013, Pages 2642-2651

  Zhou, Weichen ^a   Zhang, Feng ^a   Chen, Xiaoli ^b,c   Shen, Yiping ^b,d,e   Lupski, James R ^f,g,h   Jin, Li ^a  

^a FUDAN UNIVERSITY   (China)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c CAPITAL INSTITUTE OF PEDIATRICS   (China)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f Department of Molecular and Human Genetics ^*  (United States)

^g BAYLOR COLLEGE OF MEDICINE   (United States)

^h TEXAS CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; DNA REPLICATION; GENE DELETION; GENE DUPLICATION; GENE INSERTION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOMIC INSTABILITY; HOMOLOGOUS RECOMBINATION; NONALLELIC HOMOLOGOUS RECOMBINATION; PRIORITY JOURNAL;

CHROMOSOME BREAKPOINTS; DNA; DNA REPLICATION; GENE DELETION; GENE DOSAGE; GENE REARRANGEMENT; GENOME, HUMAN; GENOMIC INSTABILITY; GENOMIC STRUCTURAL VARIATION; HOMOLOGOUS RECOMBINATION; HUMANS; NEOPLASMS; SEGMENTAL DUPLICATIONS, GENOMIC;

EID: 84878933234     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt113     Document Type: Article

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