PINK1 rendered temperature sensitive by disease-associated and engineered mutations

Human Molecular Genetics

Volumn 22, Issue 13, 2013, Pages 2572-2589

  Narendra, Derek P ^a,b   Wang, Chunxin ^b   Youle, Richard J ^b   Walker, John E ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PARKIN; PINK1 PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; CAENORHABDITIS ELEGANS; DISEASE ASSOCIATION; DROSOPHILA MELANOGASTER; FEMALE; HELA CELL; HUMAN; HUMAN CELL; MAMMAL CELL; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TEMPERATURE SENSITIVITY; ZEBRA FISH;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ENZYME ACTIVATION; GENE EXPRESSION; GENETIC ASSOCIATION STUDIES; GENETIC VARIATION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PARKINSONIAN DISORDERS; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN KINASES; PROTEIN STABILITY; PROTEIN TRANSPORT; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

CAENORHABDITIS ELEGANS; DANIO RERIO; DROSOPHILA MELANOGASTER; MUS MUSCULUS;

EID: 84878931274     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt106     Document Type: Article

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