Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia

Leukemia

Volumn 27, Issue 6, 2013, Pages 1348-1357

  Oram, S H ^a   Thoms, J ^b   Sive, J I ^a   Calero Nieto, F J ^a   Kinston, S J ^a   Schutte J ^a   Knezevic, K ^b   Lock, R B ^b   Pimanda, J E ^b   Gottgens B ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

bivalent chromatin; LMO1; T ALL; transcriptional regulation

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BLOOD CELL; CD3+ T LYMPHOCYTE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA FLANKING REGION; EMBRYO; ENHANCER REGION; EPIGENETIC REPRESSION; EPIGENETICS; GENE EXPRESSION; GENE LOCUS; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOUSE; NERVOUS TISSUE; NONHUMAN; ONCOGENE; ONCOGENE LMO1; PRIORITY JOURNAL; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; RESTRICTION SITE; T LYMPHOCYTE;

ANIMALS; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; ENHANCER ELEMENTS, GENETIC; HUMANS; LIM DOMAIN PROTEINS; MICE; MICE, TRANSGENIC; ONCOGENES; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROMOTER REGIONS, GENETIC; TRANSCRIPTION FACTORS;

EID: 84878930633     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2013.2     Document Type: Article

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