Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

Blood

Volumn 113, Issue 23, 2009, Pages 5783-5792

  Landry, Josette Reneé ^a   Bonadies, Nicolas ^a   Kinston, Sarah ^a   Knezevic, Kathy ^a   Wilson, Nicola K ^a   Oram, S Helen ^a   Janes, Mary ^a   Piltz, Sandie ^a   Hammett, Michelle ^a   Carter, Jacinta ^a   Hamilton, Tina ^a   Donaldson, Ian J ^a   Lacaud, Georges ^b   Frampton, Jonathan ^c   Follows, George ^a   Kouskoff, Valerie ^b   Göttgens, Berthold ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b CHRISTIE HOSPITAL   (United Kingdom)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; TRANSCRIPTION FACTOR ETS; TRANSCRIPTION FACTOR GATA 2; TRANSCRIPTION FACTOR TAL1; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; LMO2 PROTEIN, MOUSE; METALLOPROTEIN; ONCOPROTEIN; TELOMERASE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR GATA;

ACUTE LEUKEMIA; ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; DNA TRANSFECTION; EMBRYO; EMBRYONIC STEM CELL; FETUS; FETUS LIVER; FLOW CYTOMETRY; GENOME; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; LEUKEMOGENESIS; LMO2 GENE; MOUSE; NONHUMAN; ONCOGENE; ONTOGENY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; REGULATORY SEQUENCE; REPORTER GENE; SEVERE COMBINED IMMUNODEFICIENCY; T CELL LEUKEMIA; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; YOLK SAC; ANIMAL; ANIMAL EMBRYO; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA; METABOLISM; PRENATAL DEVELOPMENT; PROTEIN BINDING; TISSUE MICROARRAY;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; GATA TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOME; LEUKEMIA; METALLOPROTEINS; MICE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; TELOMERASE; TISSUE ARRAY ANALYSIS; TRANS-ACTIVATORS;

EID: 67349199007     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2008-11-187757     Document Type: Article

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