An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice

EMBO Journal

Volumn 16, Issue 9, 1997, Pages 2408-2419

  Aplan, Peter D ^a,b   Jones, Craig A ^a   Chervinsky, David S ^a   Zhao, XianFeng ^a   Ellsworth, MaryKay ^a   Wu, Chuanzen ^a   McGuire, Elizabeth A ^c   Gross, Kenneth W ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

^c UNIVERSITY OF PITTSBURGH CANCER INSTITUTE   (United States)

Author keywords

Acute lymphoblastic leukemia; LMO1; scl; T cells; Transgene

Indexed keywords

GENE PRODUCT; HELIX LOOP HELIX PROTEIN; TRANSCRIPTION FACTOR;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CHROMOSOME TRANSLOCATION; FEMALE; GENE DISRUPTION; HEMATOPOIESIS; LEUKEMOGENESIS; LYMPHOBLASTOMA; MALE; MOUSE; NONHUMAN; ONCOGENE; PRIORITY JOURNAL; T CELL LEUKEMIA; TRANSACTIVATION; TRANSGENIC MOUSE;

ANIMALS; BASE SEQUENCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BINDING SITES; BONE AND BONES; DNA-BINDING PROTEINS; EXONS; GENETIC VECTORS; HELIX-LOOP-HELIX MOTIFS; HUMANS; LEUKEMIA, T-CELL, ACUTE; METALLOPROTEINS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; NUCLEAR PROTEINS; ONCOGENE PROTEINS; ONCOGENE PROTEINS, FUSION; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-PIM-1; RECOMBINATION, GENETIC; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

ANIMALIA; MUS MUSCULUS;

EID: 0030921503     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.9.2408     Document Type: Article

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