Association of common single-nucleotide polymorphisms in innate immune genes with differences in TLR-induced cytokine production in neonates

Genes and Immunity

Volumn 14, Issue 4, 2013, Pages 199-211

  Cho, P ^a   Gelinas, L ^a   Corbett, N P ^a   Tebbutt, S J ^a,b,c   Turvey, S E ^a   Fortuno, E S ^a   Kollmann, T R ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b NCE CECR PROOF Centre of Excellence   (Canada)

^c The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research   (Canada)

Author keywords

genetic association; innate immunity; neonate; race; SNP; TLR

Indexed keywords

ALPHA2 INTERFERON; CHEMOKINE; CYTOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 8; IRF PROTEIN; LIGAND; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; PROTEIN KINASE SYK; STAT PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; UNCLASSIFIED DRUG;

ARTICLE; ASIAN; AUTOIMMUNE DISEASE; COHORT ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN EXPERIMENT; IMMUNOGENETICS; IMMUNOPHENOTYPING; INFECTION RISK; INNATE IMMUNITY; MALE; NEWBORN; NORMAL HUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; VACCINATION;

ASIAN CONTINENTAL ANCESTRY GROUP; CYTOKINES; FEMALE; GENETIC ASSOCIATION STUDIES; HUMANS; IMMUNITY, INNATE; INFANT, NEWBORN; INTERFERON REGULATORY FACTORS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-TYROSINE KINASES; STAT TRANSCRIPTION FACTORS; TOLL-LIKE RECEPTOR 3; TOLL-LIKE RECEPTOR 4;

EID: 84878913574     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2013.5     Document Type: Article

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