Ethnicity greatly influences cytokine gene polymorphism distribution

American Journal of Transplantation

Volumn 2, Issue 6, 2002, Pages 560-567

  Hoffmann, Steven C ^a   Stanley, Eran M ^a   Cox, E Darrin ^b   DiMercurio, Barbara S ^a   Koziol, Deloris E ^c   Harlan, David M ^a   Kirk, Allan D ^a   Blair, Patrick J ^a,d  

^a NAVAL MEDICAL RESEARCH CENTER   (United States)

^b WALTER REED ARMY MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

Author keywords

Allotransplantation; Cytokines; Polymorphisms; Renal

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; TRANSFORMING GROWTH FACTOR ALPHA; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

ALLOIMMUNITY; ARTICLE; ASIAN; CAUCASIAN; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA POLYMORPHISM; ETHNIC GROUP; ETHNOLOGY; FEMALE; GENOTYPE; GRAFT REJECTION; HALF LIFE TIME; HUMAN; MAJOR CLINICAL STUDY; MALE; NEGRO; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

ALLELES; CYTOKINES; ETHNIC GROUPS; GENOTYPE; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; KIDNEY FAILURE, CHRONIC; POLYMORPHISM, GENETIC; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036664288     PISSN: 16006135     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-6143.2002.20611.x     Document Type: Article

References (47)

1. Dai Z, Lakkis FG. The role of cytokines, CTLA-4 and costimulation in transplant tolerance and rejection. Curr Opin Immunol 1999; 11: 504-508.
2. Sankaran D, Asderakis A, Ashraf S et al. Cytokine gene polymorphisms predict acute graft rejection following renal transplantation. Kidney Int 1999; 56: 281-288.
3. Hutchinson IV, Turner DM, Sankaran D, Awad MR, Sinnott PJ. Influence of cytokine genotypes on allograft rejection. Transplant Proc 1998; 30: 862-863.
4. Hutchinson IV, Turner D, Sankaran D, Awad M, Pravica V, Sinnott P. Cytokine genotypes in allograft rejection: guidelines for immunosuppression. Transplant Proc 1998; 30: 3991-3992.
5. Hutchinson IV, Pravica V, Sinnott P. Genetic regulation of cytokine synthesis: Consequence for acute and chronic organ allograft rejection. Graft 2000; 56: 281-286.
6. Pravica V, Asderakis A, Perrey C, Hajeer A, Sinnott PJ, Hutchinson IV. In vitro production of IFN-gamma correlates with CA repeat polymorphism in the human IFN-gamma gene. Eur J Immunogenet 1999; 26: 1-3.
7. Hoffmann SC, Stanley EM, Darrin CE et al. Association of cytokine polymorphic inheritance and in vitro cytokine production in anti-CD3/CD28-stimulated peripheral blood lymphocytes. Transplantation 2001; 72: 1444-1450.
8. Awad MR, El Gamel A, Hasleton P, Turner DM, Sinnott PJ, Hutchinson IV. Genotypic variation in the transforming growth factor-beta 1 gene: association with transforming growth factor-beta 1 production, fibrotic lung disease, and graft fibrosis after lung transplantation. Transplantation 1998; 66: 1014-1020.
9. Asderakis A, Sankaran D, Dyer P et al. Association of polymorphisms in the human interferon-gamma and interleukin-10 gene with acute and chronic kidney transplant outcome: the cytokine effect on transplantation. Transplantation 2001; 71: 674-677.
10. Turner D, Grant SC, Yonan N et al. Cytokine gene polymorphism and heart transplant rejection. Transplantation 1997; 64: 776-779.
11. Holweg CT, Baan CC, Balk AH et al. The transforming growth factor-beta1 codon 10 gene polymorphism and accelerated graft vascular disease after clinical heart transplantation. Transplantation 2001; 71: 1463-1467.
12. Awad MR, Webber S, Boyle G et al. The effect of cytokine gene polymorphisms on pediatric heart allograft outcome. J Heart Lung Transplant 2001; 20: 625-630.
13. Tambur AR, Ortegel JW, Ben Ari Z et al. Role of cytokine gene polymorphism in hepatitis C recurrence and allograft rejection among liver transplant recipients. Transplantation 2001; 71: 1475-1480.
14. Miki C, McMaster P, Mayer AD, Iriyama K, Suzuki H, Buckels JA. Factors predicting perioperative cytokine response in patients undergoing liver transplantation. Crit Care Med 2000; 28: 351-428.
15. Krakauer H, Spees EK, Vaughn WK, Grauman JS, Summe JP, Bailey RC. Assessment of prognostic factors and projection of outcomes in renal transplantation. Transplantation 1983; 36: 372-378.
16. United States Renal Data System, USRDS. Annual Data Report. Bethesda, MD: The National Institutes of Health, The National Institute of Digestive Diseases and Kidney Diseases, 1998.
17. Annual report of the U.S. Scientific Registry for Transplant Recipients and the Organ Procurement and Transplantation Network. Rockville, MD: US Department of Health and Human Services, 2000.
18. Young CJ, Gaston RS. Renal transplantation in black Americans. N Engl J Med 2000; 343: 1545-1552.
19. Cecka JM. The UNOS Scientific Renal Transplant Registry. Clin Transplant 1998; V: 1-16.
20. Tornatore KM, Biocevich DM, Reed K, Tousley K, Singh JP, Venuto RC. Methylprednisolone pharmacokinetics, cortisol response, and adverse effects in black and white renal transplant recipients. Transplantation 1995; 59: 729-736.
21. Lindholm A, Welsh M, Alton C, Kahan BD. Demographic factors influencing cyclosporine pharmacokinetic parameters in patients with uremia: racial differences in bioavailability. Clin Pharmacol Ther 1992; 52: 359-371.
22. Hutchings A, Purcell WM, Benfield MR. Peripheral blood antigen-presenting cells from African-Americans exhibit increased CD80 and CD86 expression. Clin Exp Immunol 1999; 118: 247-252.
23. Kerman RH, Kimball PM, Van Buren CT, Lewis RM, Kahan BD. Stronger immune responsiveness of blacks vs whites may account for renal allograft survival differences. Transplant Proc 1991; 23: 380-382.
24. Gaston RS, Hudson SL, Deierhoi MH et al. Improved survival of primary cadaveric renal allografts in blacks with quadruple immunosuppression. Transplantation 1992; 53: 103-109.
25. Cox ED, Hoffmann SC, DiMercurio BS et al. Cytokine polymorphic analyses indicate ethnic differences in the allelic distribution of interleukin-2 and interleukin-6. Transplantation 2001; 72: 720-726.
26. Holm S. A simple sequentially rejection multiple test procedure. Scand J Statist 1979; 6: 65-70.
27. Wright SP. Adjusted p-values for simultaneous inferences: Biometrics 1992; 48: 1005-1013.
28. John S, Turner D, Donn R et al. Two novel biallelic polymorphisms in the IL-2 gene. Eur J Immunogenet 1998; 25: 419-420.
29. Fishman D, Faulds G, Jeffery R et al. The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest 1998; 102: 1369-1376.
30. Turner DM, Williams DM, Sankaran D, Lazarus M, Sinnott PJ, Hutchinson IV. An investigation of polymorphism in the interleukin-10 gene promoter. Eur J Immunogenet 1997; 24: 1-8.
31. Hutchinson IV. The role of transforming growth factor-beta in transplant rejection. Transplant Proc 1999; 31: 9S-13S.
32. Katznelson S, Cecka JM. The great success of Asian kidney transplant recipients. Transplantation 1997; 64: 1850-1852.
33. Zhou YC, Cecka JM, Terasaki PI. Effect of race on kidney transplants. Clin Transplant 1990; 44: 447-459.
34. Opelz G, Wujciak T, Schwarz V, Back D, Mytilineos J, Scherer S. Collaborative Transplant Study analysis of graft survival in blacks. Transplant Proc 1993; 25: 2443-2445.
35. Butkus DE, Dottes AL, Meydrech EF, Barber WH. Effect of poverty and other socioeconomic variables on renal allograft survival. Transplantation 2001; 72: 261-266.
36. Suthanthiran M, Khanna A, Cukran D et al. Transforming growth factor-beta 1 hyperexpression in African American end-stage renal disease patients. Kidney Int 1998; 53: 639-644.
37. Scantlebury V, Gjertson D, Eliasziw M et al. Effect of HLA mismatch in African-Americans. Transplantation 1998; 65: 586-588.
38. Ahsan N, Hricik D, Matas A et al. Prednisone withdrawal in kidney transplant recipients on cyclosporine and mycophenolate mofetil - a prospective randomized study. Steroid Withdrawal Study Group. Transplantation 1999; 68: 1865-1874.
39. Van Parijs L, Perez VL, Abbas AK. Mechanisms of peripheral T cell tolerance. Novartis Found Symp 1998; 33: 5-14.
40. Li Y, Li XC, Zheng XX, Wells AD, Turka LA, Strom TB. Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance [In Process Citation]. Nat Med 1999; 5: 1298-1302.
41. Marshall SE, McLaren AJ, Haldar NA, Bunce M, Morris PJ, Welsh KI. The impact of recipient cytokine genotype on acute rejection after renal transplantation. Transplantation 2000; 70: 1485-1491.
42. Lowry RP, Konieczny B, Alexander D et al. Interleukin-10 eliminates anti-CD3 monoclonal antibody-induced mortality and prolongs heart allograft survival in inbred mice. Transplant Proc 1995; 27: 392-394.
43. Mottram PL, Han WR, Purcell LJ, McKenzie IF, Hancock WW. Increased expression of IL-4 and IL-10 and decreased expression of IL-2 and interferon-gamma in long-surviving mouse heart allografts after brief CD4-monoclonal antibody therapy. Transplantation 1995; 59: 559-565.
44. Zheng XX, Steele AW, Nickerson PW, Steurer W, Steiger J, Strom TB. Administration of noncytolytic IL-10/Fc in murine models of lipopolysaccharide-induced septic shock and allogeneic islet transplantation. J Immunol 1995; 154: 5590-5600.
45. Vandenbroecke C, Caillat-Zucman S, Legendre C et al. Differential in situ expression of cytokines in renal allograft rejection. Transplantation 1991; 51: 602-609.
46. Kaminski ER, Kaminski A, Bending MR et al. In vitro cytokine profiles and their relevance to rejection following renal transplantation. Transplantation 1995; 60: 703-706.
47. Li B, Khanna A, Sharma V, Singh T, Suthanthiran M, August P. TGF-beta1 DNA polymorphisms, protein levels, and blood pressure. Hypertension 1999; 33: 271-275.