Metabolomic Analysis Reveals Extended Metabolic Consequences of Marginal Vitamin B-6 Deficiency in Healthy Human Subjects

PLoS ONE

Volumn 8, Issue 6, 2013, Pages

  Gregory III, Jesse F ^a   Park, Youngja ^b,i   Lamers, Yvonne ^a,h   Bandyopadhyay, Nirmalya ^c   Chi, Yueh Yun ^d   Lee, Kichen ^b,e   Kim, Steven ^b   da Silva, Vanessa ^a   Hove, Nikolas ^e   Ranka, Sanjay ^c   Kahveci, Tamer ^c   Muller, Keith E ^d   Stevens, Robert D ^f   Newgard, Christopher B ^f   Stacpoole, Peter W ^g   Jones, Dean P ^b  

^a UNIVERSITY OF FLORIDA   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c J Crayton Pruitt Family Department of Biomedical Engineering   (United States)

^d UNIVERSITY OF FLORIDA   (United States)

^e Hanyang University   (South Korea)

^f DUKE UNIVERSITY MEDICAL CENTER   (United States)

^g UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^h UNIVERSITY OF BRITISH COLUMBIA   (Canada)

ⁱ Korea University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; ACETIC ACID; ACYLCARNITINE; AMINO ACID; CYSTATHIONINE; GLUTAMIC ACID; GLUTAMINE; PROLINE; PYRIDOXAL 5 PHOSPHATE; PYRIDOXINE; PYRUVIC ACID; TRIMETHYLAMINE OXIDE;

ADULT; AMINO ACID BLOOD LEVEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIET RESTRICTION; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MASS SPECTROMETRY; METABOLOMICS; NORMAL HUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PYRIDOXINE DEFICIENCY; QUANTITATIVE ANALYSIS; VITAMIN BLOOD LEVEL; VITAMIN INTAKE;

ACETATES; ADULT; AMINO ACIDS; CARNITINE; CYSTATHIONINE; FEMALE; GLUTAMIC ACID; GLUTAMINE; HUMANS; KETOGLUTARIC ACIDS; MALE; METABOLOMICS; PROLINE; PYRIDOXAL PHOSPHATE; VITAMIN B 6; VITAMIN B 6 DEFICIENCY; YOUNG ADULT;

EID: 84878913304     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063544     Document Type: Article

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