메뉴 건너뛰기




Volumn 14, Issue 4, 2013, Pages 271-276

Intrinsic bias and public rearrangements in the human immunoglobulin Vλ light chain repertoire

Author keywords

CDR L3; human; humanized mice; immunoglobulin repertoire; lambda light chain; next generation sequencing

Indexed keywords

IMMUNOGLOBULIN LAMBDA CHAIN;

EID: 84878904050     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2013.10     Document Type: Article
Times cited : (30)

References (37)
  • 1
    • 0024397697 scopus 로고
    • Physical maps of the mouse and human immunoglobulin-like loci
    • Lai E, Wilson RK, Hood LE. Physical maps of the mouse and human immunoglobulin-like loci. Adv Immunol 1989; 46: 1-59. (Pubitemid 19254748)
    • (1989) Advances in Immunology , vol.46 , pp. 1-59
    • Lai, E.1    Wilson, R.K.2    Hood, L.E.3
  • 2
    • 0030006070 scopus 로고    scopus 로고
    • Clonal selection and learning in the antibody system
    • DOI 10.1038/381751a0
    • Rajewsky K. Clonal selection and learning in the antibody system. Nature 1996; 381: 751-758. (Pubitemid 26243107)
    • (1996) Nature , vol.381 , Issue.6585 , pp. 751-758
    • Rajewsky, K.1
  • 3
    • 0025781883 scopus 로고
    • Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions
    • Sanz I. Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions. J Immunol 1991; 147: 1720-1729.
    • (1991) J Immunol , vol.147 , pp. 1720-1729
    • Sanz, I.1
  • 4
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa S. Somatic generation of antibody diversity. Nature 1983; 302: 575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 5
    • 76749113309 scopus 로고    scopus 로고
    • Structure and function of immunoglobulins
    • Schroeder Jr HW, Cavacini L. Structure and function of immunoglobulins. J Allergy Clin Immunol 2010; 125(2, Supplement 2): S41-S52.
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.2 SUPPL.EMENT. 2
    • Schroeder Jr., H.W.1    Cavacini, L.2
  • 6
    • 77954601328 scopus 로고    scopus 로고
    • Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing
    • Boyd SD, Marshall EL, Merker JD, Maniar JM, Zhang LN, Sahaf B et al. Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing. Sci Transl Med 2009; 1: 12ra23.
    • (2009) Sci Transl Med , vol.1
    • Boyd, S.D.1    Marshall, E.L.2    Merker, J.D.3    Maniar, J.M.4    Zhang, L.N.5    Sahaf, B.6
  • 7
    • 73949116413 scopus 로고    scopus 로고
    • Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire
    • Glanville J, Zhai W, Berka J, Telman D, Huerta G, Mehta GR et al. Precise determination of the diversity of a combinatorial antibody library gives insight into the human immunoglobulin repertoire. Proc Natl Acad Sci USA 2009; 106(48): 20216-20221.
    • (2009) Proc Natl Acad Sci USA , vol.106 , Issue.48 , pp. 20216-20221
    • Glanville, J.1    Zhai, W.2    Berka, J.3    Telman, D.4    Huerta, G.5    Mehta, G.R.6
  • 8
    • 79961160227 scopus 로고    scopus 로고
    • High-resolution description of antibody heavy-chain repertoires in humans
    • Arnaout R, Lee W, Cahill P, Honan T, Sparrow T, Weiand M et al. High-resolution description of antibody heavy-chain repertoires in humans. PLoS One 2011; 6: e22365.
    • (2011) PLoS One , vol.6
    • Arnaout, R.1    Lee, W.2    Cahill, P.3    Honan, T.4    Sparrow, T.5    Weiand, M.6
  • 9
    • 0029063311 scopus 로고
    • Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
    • Brezinschek H, Brezinschek R, Lipsky P. Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction. J Immunol 1995; 155: 190-202.
    • (1995) J Immunol , vol.155 , pp. 190-202
    • Brezinschek, H.1    Brezinschek, R.2    Lipsky, P.3
  • 10
    • 84055181361 scopus 로고    scopus 로고
    • Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation
    • Glanville J, Kuo TC, Von Budingen H-C, Guey L, Berka J, Sundar PD et al. Naive antibody gene-segment frequencies are heritable and unaltered by chronic lymphocyte ablation. Proc Natl Acad Sci USA 2011; 108(50): 20066-20071.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.50 , pp. 20066-20071
    • Glanville, J.1    Kuo, T.C.2    Von Budingen, H.-C.3    Guey, L.4    Berka, J.5    Sundar, P.D.6
  • 12
    • 0028986909 scopus 로고
    • Representation of rearranged VH gene segments in the human adult antibody repertoire
    • Suzuki I, Pfister L, Glas A, Nottenburg C, Milner EC. Representation of rearranged VH gene segments in the human adult antibody repertoire. J Immunol 1995; 154: 3902-3911.
    • (1995) J Immunol , vol.154 , pp. 3902-3911
    • Suzuki, I.1    Pfister, L.2    Glas, A.3    Nottenburg, C.4    Milner, E.C.5
  • 13
    • 0026099589 scopus 로고
    • Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes
    • Yamada M, Wasserman R, Reichard BA, Shane S, Caton AJ, Rovera G. Preferential utilization of specific immunoglobulin heavy chain diversity and joining segments in adult human peripheral blood B lymphocytes. J Exp Med 1991; 173: 395-407.
    • (1991) J Exp Med , vol.173 , pp. 395-407
    • Yamada, M.1    Wasserman, R.2    Reichard, B.A.3    Shane, S.4    Caton, A.J.5    Rovera, G.6
  • 14
    • 77953632929 scopus 로고    scopus 로고
    • Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements
    • Boyd SD, Gaeta BA, Jackson KJ, Fire AZ, Marshall EL, Merker JD et al. Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements. J Immunol 2010; 184: 6986-6992.
    • (2010) J Immunol , vol.184 , pp. 6986-6992
    • Boyd, S.D.1    Gaeta, B.A.2    Jackson, K.J.3    Fire, A.Z.4    Marshall, E.L.5    Merker, J.D.6
  • 15
    • 0028326520 scopus 로고
    • A directory of human germ-line v kappa segments reveals a strong bias in their usage
    • Cox JP, Tomlinson IM, Winter G. A directory of human germ-line V kappa segments reveals a strong bias in their usage. Eur J Immunol 1994; 24: 827-836.
    • (1994) Eur J Immunol , vol.24 , pp. 827-836
    • Cox, J.P.1    Tomlinson, I.M.2    Winter, G.3
  • 17
    • 84857011935 scopus 로고    scopus 로고
    • Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells
    • Jackson KJL, Wang Y, Gaeta BA, Pomat W, Siba P, Rimmer J et al. Divergent human populations show extensive shared IGK rearrangements in peripheral blood B cells. Immunogenetics 2011; 64: 3-14.
    • (2011) Immunogenetics , vol.64 , pp. 3-14
    • Jackson, K.J.L.1    Wang, Y.2    Gaeta, B.A.3    Pomat, W.4    Siba, P.5    Rimmer, J.6
  • 18
    • 0031586002 scopus 로고    scopus 로고
    • The creation of diversity in the human immunoglobulin V(λ) repertoire
    • DOI 10.1006/jmbi.1997.0956
    • Ignatovich O, Tomlinson IM, Jones PT, Winter G. The creation of diversity in the human immunoglobulin Vl repertoire. J Mol Biol 1997; 268: 69-77. (Pubitemid 27192679)
    • (1997) Journal of Molecular Biology , vol.268 , Issue.1 , pp. 69-77
    • Ignatovich, O.1    Tomlinson, I.M.2    Jones, P.T.3    Winter, G.4
  • 19
    • 7844249789 scopus 로고    scopus 로고
    • Frequent N addition and clonal relatedness among immunoglobulin lambda light chains expressed in rheumatoid arthritis synovia and PBL, and the influence of v lambda gene segment utilization on CDR3 length
    • Bridges SL. Frequent N addition and clonal relatedness among immunoglobulin lambda light chains expressed in rheumatoid arthritis synovia and PBL, and the influence of V lambda gene segment utilization on CDR3 length. Mol Med 1998; 4: 525-553.
    • (1998) Mol Med , vol.4 , pp. 525-553
    • Bridges, S.L.1
  • 20
    • 0033607492 scopus 로고    scopus 로고
    • Dominance of intrinsic genetic factors in shaping the human immunoglobulin Vl repertoire
    • Ignatovich O, Tomlinson IM, Popov AV, Bruggemann M, Winter G. Dominance of intrinsic genetic factors in shaping the human immunoglobulin Vl repertoire. J Mol Biol 1999; 294: 457-465.
    • (1999) J Mol Biol , vol.294 , pp. 457-465
    • Ignatovich, O.1    Tomlinson, I.M.2    Popov, A.V.3    Bruggemann, M.4    Winter, G.5
  • 21
    • 0345436074 scopus 로고    scopus 로고
    • Molecular mechanisms and selection influence the generation of the human VλJλ repertoire
    • Farner NL, Do rner T, Lipsky PE. Molecular mechanisms and selection influence the generation of the human VlJl repertoire. J Immunol 1999; 162: 2137-2145. (Pubitemid 29288835)
    • (1999) Journal of Immunology , vol.162 , Issue.4 , pp. 2137-2145
    • Farner, N.L.1    Dorner, T.2    Lipsky, P.E.3
  • 22
    • 0034541166 scopus 로고    scopus 로고
    • The VlJl repertoire in human fetal spleen: Evidence for positive selection and extensive receptor editing
    • Lee J, Monson NL, Lipsky PE. The VlJl repertoire in human fetal spleen: evidence for positive selection and extensive receptor editing. J Immunol 2000; 165: 6322-6333.
    • (2000) J Immunol , vol.165 , pp. 6322-6333
    • Lee, J.1    Monson, N.L.2    Lipsky, P.E.3
  • 23
    • 34548242744 scopus 로고    scopus 로고
    • The lambda gene immunoglobulin repertoire of human neonatal B cells
    • DOI 10.1016/j.molimm.2007.06.155, PII S0161589007004063
    • Richl P, Stern U, Lipsky PE, Girschick HJ. The lambda gene immunoglobulin repertoire of human neonatal B cells. Mol Immunol 2008; 45: 320-327. (Pubitemid 47332643)
    • (2008) Molecular Immunology , vol.45 , Issue.2 , pp. 320-327
    • Richl, P.1    Stern, U.2    Lipsky, P.E.3    Girschick, H.J.4
  • 28
    • 34249950996 scopus 로고    scopus 로고
    • Models for antigen receptor gene rearrangement: CDR3 length
    • DOI 10.1038/sj.icb.7100055, PII 7100055
    • Saada R, Weinberger M, Shahaf G, Mehr R. Models for antigen receptor gene rearrangement: CDR3 length. Immunol Cell Biol 2007; 85: 323-332. (Pubitemid 46878931)
    • (2007) Immunology and Cell Biology , vol.85 , Issue.4 , pp. 323-332
    • Saada, R.1    Weinberger, M.2    Shahaf, G.3    Mehr, R.4
  • 29
    • 84860494449 scopus 로고    scopus 로고
    • Antibody repertoires in humanized NOD-scid-IL2Rgnull mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse
    • e35497
    • Ippolito GC, Hoi KH, Reddy ST, Carroll SM, Ge X, Rogosch T et al. Antibody repertoires in humanized NOD-scid-IL2Rgnull mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse. PLoS One 2012; 7: 4 e35497.
    • (2012) PLoS One , vol.7 , pp. 4
    • Ippolito, G.C.1    Hoi, K.H.2    Reddy, S.T.3    Carroll, S.M.4    Ge, X.5    Rogosch, T.6
  • 30
    • 0028289241 scopus 로고
    • Anatomy of the antibody molecule
    • DOI 10.1016/0161-5890(94)90001-9
    • Padlan EA. Anatomy of the antibody molecule. Mol Immunol 1994; 31: 169-217. (Pubitemid 24071681)
    • (1994) Molecular Immunology , vol.31 , Issue.3 , pp. 169-217
    • Padlan, E.A.1
  • 31
    • 0028606741 scopus 로고
    • Antibody-antigen interactions: New structures and new conformational changes
    • Wilson IA, Stanfield RL. Antibody-antigen interactions: new structures and new conformational changes. Curr Opin Struct Biol 1994; 4: 857-867.
    • (1994) Curr Opin Struct Biol , vol.4 , pp. 857-867
    • Wilson, I.A.1    Stanfield, R.L.2
  • 32
    • 0023278330 scopus 로고
    • Canonical structures for the hypervariable regions of immunoglobulins
    • Chothia C, Lesk AM. Canonical structures for the hypervariable regions of immunoglobulins. J Mol Biol 1987; 196: 901-917. (Pubitemid 17127946)
    • (1987) Journal of Molecular Biology , vol.196 , Issue.4 , pp. 901-917
    • Chothia, C.1    Lesk, A.M.2
  • 33
    • 65249106714 scopus 로고    scopus 로고
    • Systematic classification of CDR-L3 in antibodies: Implications of the light chain subtypes and the VL-VH interface
    • Kuroda D, Shirai H, Kobori M, Nakamura H. Systematic classification of CDR-L3 in antibodies: implications of the light chain subtypes and the VL-VH interface. Proteins Structure Function Bioinformatics 2009; 75: 139-146.
    • (2009) Proteins Structure Function Bioinformatics , vol.75 , pp. 139-146
    • Kuroda, D.1    Shirai, H.2    Kobori, M.3    Nakamura, H.4
  • 34
    • 84861222628 scopus 로고    scopus 로고
    • B cell receptor light chain repertoires show signs of selection with differences between groups of healthy individuals and SLE patients
    • Schoettler N, Ni D, Weigert M. B cell receptor light chain repertoires show signs of selection with differences between groups of healthy individuals and SLE patients. Mol Immunol 2012; 51: 273-282.
    • (2012) Mol Immunol , vol.51 , pp. 273-282
    • Schoettler, N.1    Ni, D.2    Weigert, M.3
  • 36
    • 77956688921 scopus 로고    scopus 로고
    • Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells
    • Reddy ST, Ge X, Miklos AE, Hughes RA, Kang SH, Hoi KH et al. Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells. Nat Biotech 2010; 28: 965-969.
    • (2010) Nat Biotech , vol.28 , pp. 965-969
    • Reddy, S.T.1    Ge, X.2    Miklos, A.E.3    Hughes, R.A.4    Kang, S.H.5    Hoi, K.H.6
  • 37
    • 48449094247 scopus 로고    scopus 로고
    • IMGT/V-QUEST: The highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis
    • Brochet X, Lefranc M-P, Giudicelli V. IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis. Nucleic Acids Res 2008; 36(Web Server issue): W503-W508.
    • (2008) Nucleic Acids Res , vol.36
    • Brochet, X.1    Lefranc, M.-P.2    Giudicelli, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.