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Volumn 294, Issue 2, 1999, Pages 457-465

Dominance of intrinsic genetic factors in shaping the human immunoglobulin V(λ) repertoire

Author keywords

Immunoglobulin; Lambda; Rearrangement; Repertoire; Transgenic mouse

Indexed keywords

DNA;

EID: 0033607492     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3243     Document Type: Article
Times cited : (16)

References (51)
  • 2
    • 0023821895 scopus 로고
    • The dynamic nature of the antibody repertoire
    • Berek C., Milstein C. The dynamic nature of the antibody repertoire. Immunol. Rev. 105:1988;5-26.
    • (1988) Immunol. Rev. , vol.105 , pp. 5-26
    • Berek, C.1    Milstein, C.2
  • 3
    • 0031901512 scopus 로고    scopus 로고
    • DNA demethylation: Turning genes on
    • Bergman Y., Mostoslavsky R. DNA demethylation: turning genes on. Biol. Chem. 379:1998;401-407.
    • (1998) Biol. Chem. , vol.379 , pp. 401-407
    • Bergman, Y.1    Mostoslavsky, R.2
  • 4
    • 0029063311 scopus 로고
    • Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction
    • Brezinschek H. P., Brezinschek H. I., Lipsky P. E. Analysis of the heavy chain repertoire of human peripheral B cells using single-cell polymerase chain reaction. J. Immunol. 155:1995;190-202.
    • (1995) J. Immunol. , vol.155 , pp. 190-202
    • Brezinschek, H.P.1    Brezinschek, H.I.2    Lipsky, P.E.3
  • 5
    • 0030610529 scopus 로고    scopus 로고
    • Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5 (-)/IgM+ B cells
    • Brezinschek H. P., Foster S. J., Brezinschek R. I., Dörner T., Domiati-Saad R., Lipsky P. E. Analysis of the human VH gene repertoire. Differential effects of selection and somatic hypermutation on human peripheral CD5(+)/IgM+ and CD5 (-)/IgM+ B cells. J. Clin. Invest. 99:1997;2488-2501.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2488-2501
    • Brezinschek, H.P.1    Foster, S.J.2    Brezinschek, R.I.3    Dörner, T.4    Domiati-Saad, R.5    Lipsky, P.E.6
  • 6
    • 0029116259 scopus 로고
    • Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individuals
    • Bridges S. L. J., Lee S. K., Johnson M. L., Lavelle J. C., Fowler P. G., Koopman W. J., Schroeder H. W. J. Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individuals. J. Clin. Invest. 96:1995;831-841.
    • (1995) J. Clin. Invest. , vol.96 , pp. 831-841
    • Bridges, S.L.J.1    Lee, S.K.2    Johnson, M.L.3    Lavelle, J.C.4    Fowler, P.G.5    Koopman, W.J.6    Schroeder, H.W.J.7
  • 8
    • 0025302613 scopus 로고
    • The early expression of some human autoantibody-associated heavy chain variable region genes is controlled by specific regulatory elements
    • Chen P. P., Soto-Gil R. W., Carson D. A. The early expression of some human autoantibody-associated heavy chain variable region genes is controlled by specific regulatory elements. Scand. J. Immunol. 31:1990;673-678.
    • (1990) Scand. J. Immunol. , vol.31 , pp. 673-678
    • Chen, P.P.1    Soto-Gil, R.W.2    Carson, D.A.3
  • 9
    • 0028986982 scopus 로고
    • The human immunoglobulin VH repertoire
    • Cook G. P., Tomlinson I. M. The human immunoglobulin VH repertoire. Immunol. Today. 16:1995;237-242.
    • (1995) Immunol. Today , vol.16 , pp. 237-242
    • Cook, G.P.1    Tomlinson, I.M.2
  • 10
    • 0028326520 scopus 로고
    • A directory of human germ-line V kappa segments reveals a strong bias in their usage
    • Cox J. P. L., Tomlinson I. M., Winter G. A directory of human germ-line V kappa segments reveals a strong bias in their usage. Eur. J. Immunol. 24:1994;827-836.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 827-836
    • Cox, J.P.L.1    Tomlinson, I.M.2    Winter, G.3
  • 11
    • 0033593356 scopus 로고    scopus 로고
    • Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire
    • De Wildt R. M. T., Hoet R. M. A., van Venrooij W. J., Tomlinson I. M., Winter G. Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire. J. Mol. Biol. 285:1999;895-901.
    • (1999) J. Mol. Biol. , vol.285 , pp. 895-901
    • De Wildt, R.M.T.1    Hoet, R.M.A.2    Van Venrooij, W.J.3    Tomlinson, I.M.4    Winter, G.5
  • 12
    • 0023948010 scopus 로고
    • High efficiency transformation of E. coli by high voltage electroporation
    • Dower W. J., Miller J. F., Ragsdale C. W. High efficiency transformation of E. coli by high voltage electroporation. Nucl. Acids Res. 16:1988;6127-6145.
    • (1988) Nucl. Acids Res. , vol.16 , pp. 6127-6145
    • Dower, W.J.1    Miller, J.F.2    Ragsdale, C.W.3
  • 14
    • 0030985603 scopus 로고    scopus 로고
    • Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells
    • Foster S. J., Brezinschek H. P., Brezinschek R. I., Lipsky P. E. Molecular mechanisms and selective influences that shape the kappa gene repertoire of IgM+ B cells. J. Clin. Invest. 99:1997;1614-1627.
    • (1997) J. Clin. Invest. , vol.99 , pp. 1614-1627
    • Foster, S.J.1    Brezinschek, H.P.2    Brezinschek, R.I.3    Lipsky, P.E.4
  • 15
    • 0028182887 scopus 로고
    • Positive and negative selection of antibody repertoires during B-cell differentiation
    • Grandien A., Modigliani Y., Freitas A., Andersson J., Coutinho A. Positive and negative selection of antibody repertoires during B-cell differentiation. Immunol. Rev. 137:1994;53-89.
    • (1994) Immunol. Rev. , vol.137 , pp. 53-89
    • Grandien, A.1    Modigliani, Y.2    Freitas, A.3    Andersson, J.4    Coutinho, A.5
  • 17
    • 0024691453 scopus 로고
    • V(D)J recombination: A functional definition of the joining signals
    • Hesse J. E., Lieber M. R., Mizuuchi K., Gellert M. V(D)J recombination: a functional definition of the joining signals. Genes Dev. 3:1989;1053-1061.
    • (1989) Genes Dev. , vol.3 , pp. 1053-1061
    • Hesse, J.E.1    Lieber, M.R.2    Mizuuchi, K.3    Gellert, M.4
  • 18
    • 0025740577 scopus 로고
    • Multi-subunit proteins on the surface of filamentous phage: Methodologies for displaying antibody (Fab) heavy and light chains
    • Hoogenboom H. R., Griffiths A. D., Johnson K. S., Chiswell D. J., Hudson P., Winter G. Multi-subunit proteins on the surface of filamentous phage: methodologies for displaying antibody (Fab) heavy and light chains. Nucl. Acids Res. 19:1991;4133-4137.
    • (1991) Nucl. Acids Res. , vol.19 , pp. 4133-4137
    • Hoogenboom, H.R.1    Griffiths, A.D.2    Johnson, K.S.3    Chiswell, D.J.4    Hudson, P.5    Winter, G.6
  • 19
    • 0026772275 scopus 로고
    • Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes
    • Huang C., Stewart A. K., Schwartz R. S., Stollar B. D. Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes. J. Clin. Invest. 89:1992;1331-1343.
    • (1992) J. Clin. Invest. , vol.89 , pp. 1331-1343
    • Huang, C.1    Stewart, A.K.2    Schwartz, R.S.3    Stollar, B.D.4
  • 20
    • 0030130977 scopus 로고    scopus 로고
    • Non-stochastic utilization of Ig V region genes in unselected human peripheral B cells
    • Huang S. C., Jiang R., Glas A. M., Milner E. C. Non-stochastic utilization of Ig V region genes in unselected human peripheral B cells. Mol. Immunol. 33:1996;553-560.
    • (1996) Mol. Immunol. , vol.33 , pp. 553-560
    • Huang, S.C.1    Jiang, R.2    Glas, A.M.3    Milner, E.C.4
  • 25
    • 0027428398 scopus 로고
    • Expressed human immunoglobulin kappa genes and their hypermutation
    • Klein R., Jaenichen R., Zachau H. G. Expressed human immunoglobulin kappa genes and their hypermutation. Eur. J. Immunol. 23:1993;3248-3262.
    • (1993) Eur. J. Immunol. , vol.23 , pp. 3248-3262
    • Klein, R.1    Jaenichen, R.2    Zachau, H.G.3
  • 26
    • 0031759422 scopus 로고    scopus 로고
    • Proteolytic selection for protein folding using filamentous bacteriophages
    • Kristensen P., Winter G. Proteolytic selection for protein folding using filamentous bacteriophages. Fold. Des. 3:1998;321-328.
    • (1998) Fold. Des. , vol.3 , pp. 321-328
    • Kristensen, P.1    Winter, G.2
  • 27
    • 0026024264 scopus 로고
    • Induced rearrangement of kappa genes in the BLIN-1 human pre-B cell line correlates with germline J-C kappa and V kappa transcription
    • Martin D., Huang R. Q., LeBien T., Van Ness B. Induced rearrangement of kappa genes in the BLIN-1 human pre-B cell line correlates with germline J-C kappa and V kappa transcription. J. Exp. Med. 173:1991;639-645.
    • (1991) J. Exp. Med. , vol.173 , pp. 639-645
    • Martin, D.1    Huang, R.Q.2    Lebien, T.3    Van Ness, B.4
  • 29
  • 31
    • 0030600454 scopus 로고    scopus 로고
    • Assembly and extension of yeast artificial chromosomes to build up a large locus
    • Popov A. V., Butzler C., Frippiat J. P., Lefranc M. P., Bruggemann M. Assembly and extension of yeast artificial chromosomes to build up a large locus. Gene. 177:1996;195-201.
    • (1996) Gene , vol.177 , pp. 195-201
    • Popov, A.V.1    Butzler, C.2    Frippiat, J.P.3    Lefranc, M.P.4    Bruggemann, M.5
  • 32
    • 0033577853 scopus 로고    scopus 로고
    • A human immunoglobulin lambda locus is similarly well expressed in mice and humans
    • Popov A. V., Zou X., Xian J., Nicholson I. C., Bruggemann M. A human immunoglobulin lambda locus is similarly well expressed in mice and humans. J. Exp. Med. 189:1999;1611-1620.
    • (1999) J. Exp. Med. , vol.189 , pp. 1611-1620
    • Popov, A.V.1    Zou, X.2    Xian, J.3    Nicholson, I.C.4    Bruggemann, M.5
  • 33
    • 0030483540 scopus 로고    scopus 로고
    • Receptor editing, immune diversification, and self-tolerance
    • Radic M. Z., Zouali M. Receptor editing, immune diversification, and self-tolerance. Immunity. 5:1996;505-511.
    • (1996) Immunity , vol.5 , pp. 505-511
    • Radic, M.Z.1    Zouali, M.2
  • 34
    • 0025788230 scopus 로고
    • Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain
    • Ramsden D. A., Wu G. E. Mouse kappa light-chain recombination signal sequences mediate recombination more frequently than do those of lambda light chain. Proc. Natl Acad. Sci. USA. 88:1991;10721-10725.
    • (1991) Proc. Natl Acad. Sci. USA , vol.88 , pp. 10721-10725
    • Ramsden, D.A.1    Wu, G.E.2
  • 35
    • 0030299042 scopus 로고    scopus 로고
    • Analysis of the VH3 repertoire among genetically disparate individuals
    • Rao S. P., Huang S. C., Milner E. C. Analysis of the VH3 repertoire among genetically disparate individuals. Exp. Clin. Immunogenet. 13:1996;131-138.
    • (1996) Exp. Clin. Immunogenet. , vol.13 , pp. 131-138
    • Rao, S.P.1    Huang, S.C.2    Milner, E.C.3
  • 36
    • 0024435908 scopus 로고
    • Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription
    • Schlissel M. S., Baltimore D. Activation of immunoglobulin kappa gene rearrangement correlates with induction of germline kappa gene transcription. Cell. 58:1989;1001-1007.
    • (1989) Cell , vol.58 , pp. 1001-1007
    • Schlissel, M.S.1    Baltimore, D.2
  • 37
    • 0027409765 scopus 로고
    • High-frequency representation of a single VH gene in the expressed human B cell repertoire
    • Stewart A. K., Huang C., Stollar B. D., Schwartz R. S. High-frequency representation of a single VH gene in the expressed human B cell repertoire. J. Exp. Med. 177:1993;409-418.
    • (1993) J. Exp. Med. , vol.177 , pp. 409-418
    • Stewart, A.K.1    Huang, C.2    Stollar, B.D.3    Schwartz, R.S.4
  • 38
    • 0028896267 scopus 로고
    • A mutated promoter of a human Ig V lambda gene segment is associated with reduced germ-line transcription and a low frequency of rearrangement
    • Stiernholm N. B., Berinstein N. L. A mutated promoter of a human Ig V lambda gene segment is associated with reduced germ-line transcription and a low frequency of rearrangement. J. Immunol. 154:1995;1748-1761.
    • (1995) J. Immunol. , vol.154 , pp. 1748-1761
    • Stiernholm, N.B.1    Berinstein, N.L.2
  • 39
    • 0028986909 scopus 로고
    • Representation of rearranged VH gene segments in the human adult antibody repertoire
    • Suzuki I., Pfister L., Glas A., Nottenburg C., Milner E. C. Representation of rearranged VH gene segments in the human adult antibody repertoire. J. Immunol. 154:1995;3902-3911.
    • (1995) J. Immunol. , vol.154 , pp. 3902-3911
    • Suzuki, I.1    Pfister, L.2    Glas, A.3    Nottenburg, C.4    Milner, E.C.5
  • 40
    • 0026785856 scopus 로고
    • The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops
    • Tomlinson I. M., Walter G., Marks J. D., Llewelyn M. B., Winter G. The repertoire of human germline VH sequences reveals about fifty groups of VH segments with different hypervariable loops. J. Mol. Biol. 227:1992;776-798.
    • (1992) J. Mol. Biol. , vol.227 , pp. 776-798
    • Tomlinson, I.M.1    Walter, G.2    Marks, J.D.3    Llewelyn, M.B.4    Winter, G.5
  • 43
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa S. Somatic generation of antibody diversity. Nature. 302:1983;575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 44
    • 0027363560 scopus 로고
    • The Nobel lectures in immunology. The Nobel prize for physiology or medicine, 1987. Somatic generation of immune diversity
    • Tonegawa S. The Nobel lectures in immunology. The Nobel prize for physiology or medicine, 1987. Somatic generation of immune diversity. Scand. J. Immunol. 38:1993;303-319.
    • (1993) Scand. J. Immunol. , vol.38 , pp. 303-319
    • Tonegawa, S.1
  • 45
    • 0027536627 scopus 로고
    • Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: Gene-segment use in mu and gamma transcripts
    • Tuaillon N., Taylor L. D., Lonberg N., Tucker P. W., Capra J. D. Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: gene-segment use in mu and gamma transcripts. Proc. Natl Acad. Sci. USA. 90:1993;3720-3724.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 3720-3724
    • Tuaillon, N.1    Taylor, L.D.2    Lonberg, N.3    Tucker, P.W.4    Capra, J.D.5
  • 46
    • 0028348205 scopus 로고
    • Limited junctional diversity in kappa light chains. Junctional sequences from CD43+B220+ early B cell progenitors resemble those from peripheral B cells
    • Victor K. D., Vu K., Feeney A. J. Limited junctional diversity in kappa light chains. Junctional sequences from CD43+B220+ early B cell progenitors resemble those from peripheral B cells. J. Immunol. 152:1994;3467-3475.
    • (1994) J. Immunol. , vol.152 , pp. 3467-3475
    • Victor, K.D.1    Vu, K.2    Feeney, A.J.3
  • 47
    • 0028109655 scopus 로고
    • The diversity of antigen-specific monoclonal antibodies from transgenic mice bearing human immunoglobulin gene miniloci
    • Wagner S. D., Popov A. V., Davies S. L., Xian J., Neuberger M. S., Brüggemann M. The diversity of antigen-specific monoclonal antibodies from transgenic mice bearing human immunoglobulin gene miniloci. Eur. J. Immunol. 24:1994;2672-2681.
    • (1994) Eur. J. Immunol. , vol.24 , pp. 2672-2681
    • Wagner, S.D.1    Popov, A.V.2    Davies, S.L.3    Xian, J.4    Neuberger, M.S.5    Brüggemann, M.6
  • 48
    • 0028180135 scopus 로고
    • Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal
    • Weber J. C., Blaison G., Martin T., Knapp A. M., Pasquali J. L. Evidence that the V kappa III gene usage is nonstochastic in both adult and newborn peripheral B cells and that peripheral CD5+ adult B cells are oligoclonal. J. Clin. Invest. 93:1994;2093-2105.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2093-2105
    • Weber, J.C.1    Blaison, G.2    Martin, T.3    Knapp, A.M.4    Pasquali, J.L.5
  • 50
    • 0025978976 scopus 로고
    • Man-made antibodies
    • Winter G., Milstein C. Man-made antibodies. Nature. 349:1991;293-299.
    • (1991) Nature , vol.349 , pp. 293-299
    • Winter, G.1    Milstein, C.2


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