Limited regeneration in long acellular nerve allografts is associated with increased Schwann cell senescence

Experimental Neurology

Volumn 247, Issue , 2013, Pages 165-177

  Saheb Al Zamani, Maryam ^a   Yan, Ying ^a   Farber, Scott J ^a   Hunter, Daniel A ^a   Newton, Piyaraj ^a   Wood, Matthew D ^a   Stewart, Sheila A ^a   Johnson, Philip J ^a   Mackinnon, Susan E ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acellular nerve allograft; Cellular senescence; Nerve autograft; Nerve grafting; Peripheral nerve; Schwann cell senescence

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; GREEN FLUORESCENT PROTEIN; INTERLEUKIN 6; THY 1 ANTIGEN;

ACELLULAR NERVE ALLOGRAFT; ALLOGRAFT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOGRAFT; CELL AGING; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME DISORDER; COHORT ANALYSIS; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GRAFT FAILURE; MALE; NERVE FIBER REGENERATION; NERVE GRAFT; NONHUMAN; PRIORITY JOURNAL; RAT; SCHWANN CELL; SCIATIC NERVE; TRANSGENIC RAT;

4′,6-DIAMIDINO-2-PHENYLINDOLE; ACELLULAR NERVE ALLOGRAFT; ACELLULARIZED NERVE ALLOGRAFTS; ANAS; CELLULAR SENESCENCE; DAPI; EDL; EXTENSOR DIGITORUM LONGUS; GFP; GREEN FLUORESCENT PROTEIN; NERVE AUTOGRAFT; NERVE GRAFTING; PERIPHERAL NERVE; SCHWANN CELL SENESCENCE; SCHWANN CELLS; SCS; SENESCENT SCHWANN CELLS; SENSCS;

ANIMALS; BETA-GALACTOSIDASE; CASPASE 3; CHROMATIN; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; GREEN FLUORESCENT PROTEINS; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; NERVE REGENERATION; NEUROMUSCULAR JUNCTION; RATS; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; RECOVERY OF FUNCTION; S100 PROTEINS; SCHWANN CELLS; SCIATIC NERVE; SCIATIC NEUROPATHY; TRANSPLANTATION, HOMOLOGOUS;

EID: 84878885627     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2013.04.011     Document Type: Article

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