Oxadiazolo pyrrolidine carboxamides as enoyl-ACP reductase inhibitors: Design, synthesis and antitubercular activity screening

Medicinal Chemistry Research

Volumn 22, Issue 7, 2013, Pages 3428-3433

  Sonia, George ^a   Ravi, Thengungal Kochupappy ^a  

^a SRI RAMAKRISHNA INSTITUTE OF PARAMEDICAL SCIENCES   (India)

Author keywords

Antitubercular activities; Docking; Enoyl acyl carrier protein (ACP); Oxadiazole; Pyrrolidine carboxamides; Reductase inhibitors

Indexed keywords

5 OXO 1 PHENYL N (5 PHENYL 1,3,4 OXADIAZOL 2 YL) PYRROLIDINE 3 CARBOXAMIDE; AMIDE; CARBOXYLIC ACID; ENOYL ACYL CARRIER PROTEIN REDUCTASE INHIBITOR; N [5 (4 CHLOROPHENYL) 1,3,4 OXADIAZOL 2 YL] 5 OXO 1 PHENYLPYRROLIDINE 3 CARBOXAMIDE; N [5 (4 METHOXYPHENYL) 1,3,4 OXADIAZOL 2 YL] 5 OXO 1 PHENYLPYRROLIDINE 3 CARBOXAMIDE; N [5 (4 METHYLPHENYL) 1,3,4 OXADIAZOL 2 YL] 5 OXO 1 PHENYLPYRROLIDINE 3 CARBOXAMIDE; N [5 (4 NITROPHENYL) 1,3,4 OXADIAZOL 2 YL] 5 OXO 1 PHENYLPYRROLIDINE 3 CARBOXAMIDE; OXADIAZOLE DERIVATIVE; OXIDOREDUCTASE INHIBITOR; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING AFFINITY; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; IN VITRO STUDY; MELTING POINT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; SCREENING TEST; THIN LAYER CHROMATOGRAPHY;

EID: 84878884350     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-012-0340-3     Document Type: Article

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